Modeling neuronal consequences of autism-associated gene regulatory variants with human induced pluripotent stem cells

por Ross, P. Joel, Mok, Rebecca S. F., Smith, Brandon S., Rodrigues, Deivid C., Mufteev, Marat, Scherer, Stephen W., Ellis, James
Publicado 2020

Identification of TIA1 mRNA targets during human neuronal development

por Byres, Loryn P., Mufteev, Marat, Yuki, Kyoko E., Wei, Wei, Piekna, Alina, Wilson, Michael D., Rodrigues, Deivid C., Ellis, James
Publicado 2021

Transcriptional buffering and 3ʹUTR lengthening are shaped during human neurodevelopment by shifts in mRNA stability and microRNA load

por Mufteev, Marat, Rodrigues, Deivid C., Yuki, Kyoko E., Narula, Ashrut, Wei, Wei, Piekna, Alina, Liu, Jiajie, Pasceri, Peter, Rissland, Olivia S., Wilson, Michael D., Ellis, James
Publicado 2023

Buffering of transcription rate by mRNA half-life is a conserved feature of Rett syndrome models

por Rodrigues, Deivid C., Mufteev, Marat, Yuki, Kyoko E., Narula, Ashrut, Wei, Wei, Piekna, Alina, Liu, Jiajie, Pasceri, Peter, Rissland, Olivia S., Wilson, Michael D., Ellis, James
Publicado 2023

Disruption of DDX53 coding sequence has limited impact on iPSC-derived human NGN2 neurons

por Faheem, Muhammad, Deneault, Eric, Alexandrova, Roumiana, Rodrigues, Deivid C., Pellecchia, Giovanna, Shum, Carole, Zarrei, Mehdi, Piekna, Alina, Wei, Wei, Howe, Jennifer L., Thiruvahindrapuram, Bhooma, Lamoureux, Sylvia, Ross, P. Joel, Bradley, Clarrisa A., Ellis, James, Scherer, Stephen W.
Publicado 2023

Reprogramming to a pluripotent state modifies mesenchymal stem cell resistance to oxidative stress

por Asensi, Karina D, Fortunato, Rodrigo S, dos Santos, Danúbia S, Pacheco, Thaísa S, de Rezende, Danielle F, Rodrigues, Deivid C, Mesquita, Fernanda C P, Kasai-Brunswick, Tais H, de Carvalho, Antonio C Campos, Carvalho, Denise P, Carvalho, Adriana B, Goldenberg, Regina C dos S
Publicado 2014

CNTN5(-)(/+)or EHMT2(-)(/+)human iPSC-derived neurons from individuals with autism develop hyperactive neuronal networks

por Deneault, Eric, Faheem, Muhammad, White, Sean H, Rodrigues, Deivid C, Sun, Song, Wei, Wei, Piekna, Alina, Thompson, Tadeo, Howe, Jennifer L, Chalil, Leon, Kwan, Vickie, Walker, Susan, Pasceri, Peter, Roth, Frederick P, Yuen, Ryan KC, Singh, Karun K, Ellis, James, Scherer, Stephen W
Publicado 2019

SHANK2 mutations associated with Autism Spectrum Disorder cause hyperconnectivity of human neurons

por Zaslavsky, Kirill, Zhang, Wen-Bo, McCready, Fraser P., Rodrigues, Deivid C., Deneault, Eric, Loo, Caitlin, Zhao, Melody, Ross, P. Joel, Hajjar, Joelle El, Romm, Asli, Thompson, Tadeo, Piekna, Alina, Wei, Wei, Wang, Zhuozhi, Khattak, Shahryar, Mufteev, Marat, Pasceri, Peter, Scherer, Stephen W., Salter, Michael W., Ellis, James
Publicado 2019

Wide spectrum of neuronal and network phenotypes in human stem cell-derived excitatory neurons with Rett syndrome-associated MECP2 mutations

por Mok, Rebecca S. F., Zhang, Wenbo, Sheikh, Taimoor I., Pradeepan, Kartik, Fernandes, Isabella R., DeJong, Leah C., Benigno, Gabriel, Hildebrandt, Matthew R., Mufteev, Marat, Rodrigues, Deivid C., Wei, Wei, Piekna, Alina, Liu, Jiajie, Muotri, Alysson R., Vincent, John B., Muller, Lyle, Martinez-Trujillo, Julio, Salter, Michael W., Ellis, James
Publicado 2022

Complete Disruption of Autism-Susceptibility Genes by Gene Editing Predominantly Reduces Functional Connectivity of Isogenic Human Neurons

por Deneault, Eric, White, Sean H., Rodrigues, Deivid C., Ross, P. Joel, Faheem, Muhammad, Zaslavsky, Kirill, Wang, Zhuozhi, Alexandrova, Roumiana, Pellecchia, Giovanna, Wei, Wei, Piekna, Alina, Kaur, Gaganjot, Howe, Jennifer L., Kwan, Vickie, Thiruvahindrapuram, Bhooma, Walker, Susan, Lionel, Anath C., Pasceri, Peter, Merico, Daniele, Yuen, Ryan K.C., Singh, Karun K., Ellis, James, Scherer, Stephen W.
Publicado 2018

Complete Disruption of Autism-Susceptibility Genes by Gene Editing Predominantly Reduces Functional Connectivity of Isogenic Human Neurons

por Deneault, Eric, White, Sean H., Rodrigues, Deivid C., Ross, P. Joel, Faheem, Muhammad, Zaslavsky, Kirill, Wang, Zhuozhi, Alexandrova, Roumiana, Pellecchia, Giovanna, Wei, Wei, Piekna, Alina, Kaur, Gaganjot, Howe, Jennifer L., Kwan, Vickie, Thiruvahindrapuram, Bhooma, Walker, Susan, Lionel, Anath C., Pasceri, Peter, Merico, Daniele, Yuen, Ryan K.C., Singh, Karun K., Ellis, James, Scherer, Stephen W.
Publicado 2019

Improvement of cardiac function by placenta-derived mesenchymal stem cells does not require permanent engraftment and is independent of the insulin signaling pathway

por Passipieri, Juliana A, Kasai-Brunswick, Tais H, Suhett, Grazielle, Martins, Andreza B, Brasil, Guilherme V, Campos, Dilza B, Rocha, Nazareth N, Ramos, Isalira P, Mello, Debora B, Rodrigues, Deivid C, Christie, Beatriz B, Silva-Mendes, Bernardo J, Balduíno, Alex, Sá, Renato M, Lopes, Laudelino M, Goldenberg, Regina C, Campos de Carvalho, Antonio C, Carvalho, Adriana B
Publicado 2014

Precision Health Resource of Control iPSC Lines for Versatile Multilineage Differentiation

por Hildebrandt, Matthew R., Reuter, Miriam S., Wei, Wei, Tayebi, Naeimeh, Liu, Jiajie, Sharmin, Sazia, Mulder, Jaap, Lesperance, L. Stephen, Brauer, Patrick M., Mok, Rebecca S.F., Kinnear, Caroline, Piekna, Alina, Romm, Asli, Howe, Jennifer, Pasceri, Peter, Meng, Guoliang, Rozycki, Matthew, Rodrigues, Deivid C., Martinez, Elisa C., Szego, Michael J., Zúñiga-Pflücker, Juan C., Anderson, Michele K., Prescott, Steven A., Rosenblum, Norman D., Kamath, Binita M., Mital, Seema, Scherer, Stephen W., Ellis, James
Publicado 2019