Compare and Contrast Meta Analysis (CCMA): A Method for Identification of Pleiotropic Loci in Genome-Wide Association Studies

por Baurecht, Hansjörg, Hotze, Melanie, Rodríguez, Elke, Manz, Judith, Weidinger, Stephan, Cordell, Heather J., Augustin, Thomas, Strauch, Konstantin
Publicado 2016

Skin Barrier and Inflammation Genes Associated with Atopic Dermatitis are Regulated by Interleukin-13 and Modulated by Tralokinumab In vitro

por TOLLENAERE, Maxim A. X., LITMAN, Thomas, MOEBUS, Lena, RODRIGUEZ, Elke, STÖLZL, Dora, DRERUP, Katharina, WERFEL, Thomas, SCHMITT, Jochen, NORSGAARD, Hanne, WEIDINGER, Stephan
Publicado 2021

Comparison of Epidermal Barrier Integrity in Adults with Classic Atopic Dermatitis, Atopic Prurigo and Non-Atopic Prurigo Nodularis

por Fölster-Holst, Regina, Reimer, Rahel, Neumann, Claudia, Proksch, Erhardt, Rodriguez, Elke, Weidinger, Stephan, Goldust, Mohamad, Hanisch, Eckhard, Dähnhardt-Pfeiffer, Stephan, Freitag-Wolf, Sandra
Publicado 2021

miRNA expression profiles of the perilesional skin of atopic dermatitis and psoriasis patients are highly similar

por Carreras-Badosa, Gemma, Maslovskaja, Julia, Vaher, Helen, Pajusaar, Laura, Annilo, Tarmo, Lättekivi, Freddy, Hübenthal, Matthias, Rodriguez, Elke, Weidinger, Stephan, Kingo, Külli, Rebane, Ana
Publicado 2022

Effects of Early Emollient Use in Children at High Risk of Atopic Dermatitis: A German Pilot Study

por HARDER, Inken, STÖLZL, Dora, SANDER, Nicole, HARTMANN, Jan, RODRIGUEZ, Elke, MAZUR, Carsten, KERZEL, Sebastian, KABESCH, Michael, KÜSTER, Denise, SCHMITT, Jochen, FÖLSTER-HOLST, Regina, GERDES, Sascha, EMMERT, Hila, WEIDINGER, Stephan
Publicado 2023

Effects of psoriasis and psoralen exposure on the somatic mutation landscape of the skin

por Olafsson, Sigurgeir, Rodriguez, Elke, Lawson, Andrew R. J., Abascal, Federico, Huber, Axel Rosendahl, Suembuel, Melike, Jones, Philip H., Gerdes, Sascha, Martincorena, Iñigo, Weidinger, Stephan, Campbell, Peter J., Anderson, Carl A.
Publicado 2023

Network-based SNP meta-analysis identifies joint and disjoint genetic features across common human diseases

por Arnold, Matthias, Hartsperger, Mara L, Baurecht, Hansjörg, Rodríguez, Elke, Wachinger, Benedikt, Franke, Andre, Kabesch, Michael, Winkelmann, Juliane, Pfeufer, Arne, Romanos, Marcel, Illig, Thomas, Mewes, Hans-Werner, Stümpflen, Volker, Weidinger, Stephan
Publicado 2012

Genetic Variation in the Epidermal Transglutaminase Genes Is Not Associated with Atopic Dermatitis

por Liedén, Agne, Winge, Mårten C. G., Sääf, Annika, Kockum, Ingrid, Ekelund, Elisabeth, Rodriguez, Elke, Fölster-Holst, Regina, Franke, Andre, Illig, Thomas, Tengvall-Linder, Maria, Baurecht, Hansjörg, Weidinger, Stephan, Wahlgren, Carl-Fredrik, Nordenskjöld, Magnus, Bradley, Maria
Publicado 2012

Claudin-1 decrease impacts epidermal barrier function in atopic dermatitis lesions dose-dependently

por Bergmann, Sophia, von Buenau, Barbara, Vidal-y-Sy, Sabine, Haftek, Marek, Wladykowski, Ewa, Houdek, Pia, Lezius, Susanne, Duplan, Hélène, Bäsler, Katja, Dähnhardt-Pfeiffer, Stephan, Gorzelanny, Christian, Schneider, Stefan W., Rodriguez, Elke, Stölzl, Dora, Weidinger, Stephan, Brandner, Johanna M.
Publicado 2020

Host genetic factors related to innate immunity, environmental sensing and cellular functions are associated with human skin microbiota

por Moitinho-Silva, Lucas, Degenhardt, Frauke, Rodriguez, Elke, Emmert, Hila, Juzenas, Simonas, Möbus, Lena, Uellendahl-Werth, Florian, Sander, Nicole, Baurecht, Hansjörg, Tittmann, Lukas, Lieb, Wolfgang, Gieger, Christian, Peters, Annette, Ellinghaus, David, Bang, Corinna, Franke, Andre, Weidinger, Stephan, Rühlemann, Malte Christoph
Publicado 2022

RNA based individualized drug selection in breast cancer patients without patient-matched normal tissue

por Forster, Michael, Mark, Adam, Egberts, Friederike, Rosati, Elisa, Rodriguez, Elke, Stanulla, Martin, Bauerschlag, Dirk, Schem, Christian, Maass, Nicolai, Amallraja, Anu, Murphy, Karla K., Prouse, Bruce R., Sulaiman, Raed A., Young, Brandon M., Mathiak, Micaela, Hemmrich-Stanisak, Georg, Ellinghaus, David, Weidinger, Stephan, Rosenstiel, Philip, Arnold, Norbert, Leyland-Jones, Brian, Williams, Casey B., Franke, Andre, Meißner, Tobias
Publicado 2018

Genome-Wide Scan on Total Serum IgE Levels Identifies FCER1A as Novel Susceptibility Locus

por Weidinger, Stephan, Gieger, Christian, Rodriguez, Elke, Baurecht, Hansjörg, Mempel, Martin, Klopp, Norman, Gohlke, Henning, Wagenpfeil, Stefan, Ollert, Markus, Ring, Johannes, Behrendt, Heidrun, Heinrich, Joachim, Novak, Natalija, Bieber, Thomas, Krämer, Ursula, Berdel, Dietrich, von Berg, Andrea, Bauer, Carl Peter, Herbarth, Olf, Koletzko, Sibylle, Prokisch, Holger, Mehta, Divya, Meitinger, Thomas, Depner, Martin, von Mutius, Erika, Liang, Liming, Moffatt, Miriam, Cookson, William, Kabesch, Michael, Wichmann, H.-Erich, Illig, Thomas
Publicado 2008

Psoriasis and cardiometabolic traits: modest association but distinct genetic architectures

por Koch, Manja, Baurecht, Hansjörg, Ried, Janina S., Rodriguez, Elke, Schlesinger, Sabrina, Volks, Natalie, Gieger, Christian, Rückert, Ina-Maria, Heinrich, Luise, Willenborg, Christina, Smith, Catherine, Peters, Annette, Thorand, Barbara, Koenig, Wolfgang, Lamina, Claudia, Jansen, Henning, Kronenberg, Florian, Seissler, Jochen, Thiery, Joachim, Rathmann, Wolfgang, Schunkert, Heribert, Erdmann, Jeanette, Barker, Jonathan, Nair, Rajan P, Tsoi, Lam C, Elder, James T, Mrowietz, Ulrich, Weichenthal, Michael, Mucha, Sören, Schreiber, Stefan, Franke, Andre, Schmitt, Jochen, Lieb, Wolfgang, Weidinger, Stephan
Publicado 2015

A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis

por Weidinger, Stephan, Willis-Owen, Saffron A.G., Kamatani, Yoichiro, Baurecht, Hansjörg, Morar, Nilesh, Liang, Liming, Edser, Pauline, Street, Teresa, Rodriguez, Elke, O'Regan, Grainne M., Beattie, Paula, Fölster-Holst, Regina, Franke, Andre, Novak, Natalija, Fahy, Caoimhe M., Winge, Mårten C.G., Kabesch, Michael, Illig, Thomas, Heath, Simon, Söderhäll, Cilla, Melén, Erik, Pershagen, Göran, Kere, Juha, Bradley, Maria, Lieden, Agne, Nordenskjold, Magnus, Harper, John I., Mclean, W.H. Irwin, Brown, Sara J., Cookson, William O.C., Lathrop, G. Mark, Irvine, Alan D., Moffatt, Miriam F.
Publicado 2013

Exome-wide association study reveals novel psoriasis susceptibility locus at TNFSF15 and rare protective alleles in genes contributing to type I IFN signalling

por Dand, Nick, Mucha, Sören, Tsoi, Lam C, Mahil, Satveer K, Stuart, Philip E, Arnold, Andreas, Baurecht, Hansjörg, Burden, A David, Callis Duffin, Kristina, Chandran, Vinod, Curtis, Charles J, Das, Sayantan, Ellinghaus, David, Ellinghaus, Eva, Enerback, Charlotta, Esko, Tõnu, Gladman, Dafna D, Griffiths, Christopher E M, Gudjonsson, Johann E, Hoffman, Per, Homuth, Georg, Hüffmeier, Ulrike, Krueger, Gerald G, Laudes, Matthias, Lee, Sang Hyuck, Lieb, Wolfgang, Lim, Henry W, Löhr, Sabine, Mrowietz, Ulrich, Müller-Nurayid, Martina, Nöthen, Markus, Peters, Annette, Rahman, Proton, Reis, André, Reynolds, Nick J, Rodriguez, Elke, Schmidt, Carsten O, Spain, Sarah L, Strauch, Konstantin, Tejasvi, Trilokraj, Voorhees, John J, Warren, Richard B, Weichenthal, Michael, Weidinger, Stephan, Zawistowski, Matthew, Nair, Rajan P, Capon, Francesca, Smith, Catherine H, Trembath, Richard C, Abecasis, Goncalo R, Elder, James T, Franke, Andre, Simpson, Michael A, Barker, Jonathan N
Publicado 2017

Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology

por Ferreira, Manuel A, Vonk, Judith M, Baurecht, Hansjörg, Marenholz, Ingo, Tian, Chao, Hoffman, Joshua D, Helmer, Quinta, Tillander, Annika, Ullemar, Vilhelmina, van Dongen, Jenny, Lu, Yi, Rüschendorf, Franz, Esparza-Gordillo, Jorge, Medway, Chris W, Mountjoy, Edward, Burrows, Kimberley, Hummel, Oliver, Grosche, Sarah, Brumpton, Ben M, Witte, John S, Hottenga, Jouke-Jan, Willemsen, Gonneke, Zheng, Jie, Rodríguez, Elke, Hotze, Melanie, Franke, Andre, Revez, Joana A, Beesley, Jonathan, Matheson, Melanie C, Dharmage, Shyamali C, Bain, Lisa M, Fritsche, Lars G, Gabrielsen, Maiken E, Balliu, Brunilda, Nielsen, Jonas B, Zhou, Wei, Hveem, Kristian, Langhammer, Arnulf, Holmen, Oddgeir L, Løset, Mari, Abecasis, Gonçalo R, Willer, Cristen J, Arnold, Andreas, Homuth, Georg, Schmidt, Carsten O, Thompson, Philip J, Martin, Nicholas G, Duffy, David L, Novak, Natalija, Schulz, Holger, Karrasch, Stefan, Gieger, Christian, Strauch, Konstantin, Melles, Ronald B, Hinds, David A, Hübner, Norbert, Weidinger, Stephan, Magnusson, Patrik KE, Jansen, Rick, Jorgenson, Eric, Lee, Young-Ae, Boomsma, Dorret I, Almqvist, Catarina, Karlsson, Robert, Koppelman, Gerard H, Paternoster, Lavinia
Publicado 2017

Rare variant analysis in eczema identifies exonic variants in DUSP1, NOTCH4 and SLC9A4

por Grosche, Sarah, Marenholz, Ingo, Esparza-Gordillo, Jorge, Arnau-Soler, Aleix, Pairo-Castineira, Erola, Rüschendorf, Franz, Ahluwalia, Tarunveer S., Almqvist, Catarina, Arnold, Andreas, Baurecht, Hansjörg, Bisgaard, Hans, Bønnelykke, Klaus, Brown, Sara J., Bustamante, Mariona, Curtin, John A., Custovic, Adnan, Dharmage, Shyamali C., Esplugues, Ana, Falchi, Mario, Fernandez-Orth, Dietmar, Ferreira, Manuel A. R., Franke, Andre, Gerdes, Sascha, Gieger, Christian, Hakonarson, Hakon, Holt, Patrick G., Homuth, Georg, Hubner, Norbert, Hysi, Pirro G., Jarvelin, Marjo-Riitta, Karlsson, Robert, Koppelman, Gerard H., Lau, Susanne, Lutz, Manuel, Magnusson, Patrik K. E., Marks, Guy B., Müller-Nurasyid, Martina, Nöthen, Markus M., Paternoster, Lavinia, Pennell, Craig E., Peters, Annette, Rawlik, Konrad, Robertson, Colin F., Rodriguez, Elke, Sebert, Sylvain, Simpson, Angela, Sleiman, Patrick M. A., Standl, Marie, Stölzl, Dora, Strauch, Konstantin, Szwajda, Agnieszka, Tenesa, Albert, Thompson, Philip J., Ullemar, Vilhelmina, Visconti, Alessia, Vonk, Judith M., Wang, Carol A., Weidinger, Stephan, Wielscher, Matthias, Worth, Catherine L., Xu, Chen-Jian, Lee, Young-Ae
Publicado 2021

Meta-analysis identifies seven susceptibility loci involved in the atopic march

por Marenholz, Ingo, Esparza-Gordillo, Jorge, Rüschendorf, Franz, Bauerfeind, Anja, Strachan, David P., Spycher, Ben D., Baurecht, Hansjörg, Margaritte-Jeannin, Patricia, Sääf, Annika, Kerkhof, Marjan, Ege, Markus, Baltic, Svetlana, Matheson, Melanie C., Li, Jin, Michel, Sven, Ang, Wei Q., McArdle, Wendy, Arnold, Andreas, Homuth, Georg, Demenais, Florence, Bouzigon, Emmanuelle, Söderhäll, Cilla, Pershagen, Göran, de Jongste, Johan C., Postma, Dirkje S., Braun-Fahrländer, Charlotte, Horak, Elisabeth, Ogorodova, Ludmila M., Puzyrev, Valery P., Bragina, Elena Yu, Hudson, Thomas J., Morin, Charles, Duffy, David L., Marks, Guy B., Robertson, Colin F., Montgomery, Grant W., Musk, Bill, Thompson, Philip J., Martin, Nicholas G., James, Alan, Sleiman, Patrick, Toskala, Elina, Rodriguez, Elke, Fölster-Holst, Regina, Franke, Andre, Lieb, Wolfgang, Gieger, Christian, Heinzmann, Andrea, Rietschel, Ernst, Keil, Thomas, Cichon, Sven, Nöthen, Markus M., Pennell, Craig E., Sly, Peter D., Schmidt, Carsten O., Matanovic, Anja, Schneider, Valentin, Heinig, Matthias, Hübner, Norbert, Holt, Patrick G., Lau, Susanne, Kabesch, Michael, Weidinger, Stefan, Hakonarson, Hakon, Ferreira, Manuel A. R., Laprise, Catherine, Freidin, Maxim B., Genuneit, Jon, Koppelman, Gerard H., Melén, Erik, Dizier, Marie- Hélène, Henderson, A John, Lee, Young Ae
Publicado 2015

META-ANALYSIS OF GENOME-WIDE ASSOCIATION STUDIES IDENTIFIES THREE NEW RISK LOCI FOR ATOPIC DERMATITIS

por Paternoster, Lavinia, Standl, Marie, Chen, Chih-Mei, Ramasamy, Adaikalavan, Bønnelykke, Klaus, Duijts, Liesbeth, Ferreira, Manuel A, Alves, Alexessander Couto, Thyssen, Jacob P, Albrecht, Eva, Baurecht, Hansjörg, Feenstra, Bjarke, Sleiman, Patrick MA, Hysi, Pirro, Warrington, Nicole M, Curjuric, Ivan, Myhre, Ronny, Curtin, John A, Groen-Blokhuis, Maria M, Kerkhof, Marjan, Sääf, Annika, Franke, Andre, Ellinghaus, David, Fölster-Holst, Regina, Dermitzakis, Emmanouil, Montgomery, Stephen B, Prokisch, Holger, Heim, Katharina, Hartikainen, Anna-Liisa, Pouta, Anneli, Pekkanen, Juha, Blakemore, Alexandra IF, Buxton, Jessica L, Kaakinen, Marika, Duffy, David L, Madden, Pamela A, Heath, Andrew C, Montgomery, Grant W, Thompson, Philip J, Matheson, Melanie C, Le Souëf, Peter, Pourcain, Beate St, Smith, George Davey, Henderson, John, Kemp, John P, Timpson, Nicholas J, Deloukas, Panos, Ring, Susan M, Wichmann, H-Erich, Müller-Nurasyid, Martina, Novak, Natalija, Klopp, Norman, Rodríguez, Elke, McArdle, Wendy, Linneberg, Allan, Menné, Torkil, Nohr, Ellen A, Hofman, Albert, Uitterlinden, André G, van Duijn, Cornélia M, Rivadeneira, Fernando, de Jongste, Johan C, van der Valk, Ralf JP, Wjst, Matthias, Jogi, Rain, Geller, Frank, Boyd, Heather A, Murray, Jeffrey C, Kim, Cecilia, Mentch, Frank, March, Michael, Mangino, Massimo, Spector, Tim D, Bataille, Veronique, Pennell, Craig E, Holt, Patrick G, Sly, Peter, Tiesler, Carla MT, Thiering, Elisabeth, Illig, Thomas, Imboden, Medea, Nystad, Wenche, Simpson, Angela, Hottenga, Jouke-Jan, Postma, Dirkje, Koppelman, Gerard H, Smit, Henriette A, Söderhäll, Cilla, Chawes, Bo, Kreiner-Møller, Eskil, Bisgaard, Hans, Melén, Erik, Boomsma, Dorret I, Custovic, Adnan, Jacobsson, Bo, Probst-Hensch, Nicole M, Palmer, Lyle J, Glass, Daniel, Hakonarson, Hakon, Melbye, Mads, Jarvis, Deborah L, Jaddoe, Vincent WV, Gieger, Christian, Strachan, David P, Martin, Nicholas G, Jarvelin, Marjo-Riitta, Heinrich, Joachim, Evans, David M, Weidinger, Stephan
Publicado 2011

European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation

por Budu-Aggrey, Ashley, Kilanowski, Anna, Sobczyk, Maria K., Shringarpure, Suyash S., Mitchell, Ruth, Reis, Kadri, Reigo, Anu, Mägi, Reedik, Nelis, Mari, Tanaka, Nao, Brumpton, Ben M., Thomas, Laurent F., Sole-Navais, Pol, Flatley, Christopher, Espuela-Ortiz, Antonio, Herrera-Luis, Esther, Lominchar, Jesus V. T., Bork-Jensen, Jette, Marenholz, Ingo, Arnau-Soler, Aleix, Jeong, Ayoung, Fawcett, Katherine A., Baurecht, Hansjorg, Rodriguez, Elke, Alves, Alexessander Couto, Kumar, Ashish, Sleiman, Patrick M., Chang, Xiao, Medina-Gomez, Carolina, Hu, Chen, Xu, Cheng-jian, Qi, Cancan, El-Heis, Sarah, Titcombe, Philip, Antoun, Elie, Fadista, João, Wang, Carol A., Thiering, Elisabeth, Wu, Baojun, Kress, Sara, Kothalawala, Dilini M., Kadalayil, Latha, Duan, Jiasong, Zhang, Hongmei, Hadebe, Sabelo, Hoffmann, Thomas, Jorgenson, Eric, Choquet, Hélène, Risch, Neil, Njølstad, Pål, Andreassen, Ole A., Johansson, Stefan, Almqvist, Catarina, Gong, Tong, Ullemar, Vilhelmina, Karlsson, Robert, Magnusson, Patrik K. E., Szwajda, Agnieszka, Burchard, Esteban G., Thyssen, Jacob P., Hansen, Torben, Kårhus, Line L., Dantoft, Thomas M., Jeanrenaud, Alexander C.S.N., Ghauri, Ahla, Arnold, Andreas, Homuth, Georg, Lau, Susanne, Nöthen, Markus M., Hübner, Norbert, Imboden, Medea, Visconti, Alessia, Falchi, Mario, Bataille, Veronique, Hysi, Pirro, Ballardini, Natalia, Boomsma, Dorret I., Hottenga, Jouke J., Müller-Nurasyid, Martina, Ahluwalia, Tarunveer S., Stokholm, Jakob, Chawes, Bo, Schoos, Ann-Marie M., Esplugues, Ana, Bustamante, Mariona, Raby, Benjamin, Arshad, Syed, German, Chris, Esko, Tõnu, Milani, Lili A., Metspalu, Andres, Terao, Chikashi, Abuabara, Katrina, Løset, Mari, Hveem, Kristian, Jacobsson, Bo, Pino-Yanes, Maria, Strachan, David P., Grarup, Niels, Linneberg, Allan, Lee, Young-Ae, Probst-Hensch, Nicole, Weidinger, Stephan, Jarvelin, Marjo-Riitta, Melén, Erik, Hakonarson, Hakon, Irvine, Alan D., Jarvis, Deborah, Nijsten, Tamar, Duijts, Liesbeth, Vonk, Judith M., Koppelmann, Gerard H., Godfrey, Keith M., Barton, Sheila J., Feenstra, Bjarke, Pennell, Craig E., Sly, Peter D., Holt, Patrick G., Williams, L. Keoki, Bisgaard, Hans, Bønnelykke, Klaus, Curtin, John, Simpson, Angela, Murray, Clare, Schikowski, Tamara, Bunyavanich, Supinda, Weiss, Scott T., Holloway, John W., Min, Josine L., Brown, Sara J., Standl, Marie, Paternoster, Lavinia
Publicado 2023