Structures of SARS-CoV-2 N7-methyltransferase with DOT1L and PRMT7 inhibitors provide a platform for new antivirals

por Kottur, Jithesh, White, Kris M., Rodriguez, M. Luis, Rechkoblit, Olga, Quintana-Feliciano, Richard, Nayar, Ahana, García-Sastre, Adolfo, Aggarwal, Aneel K.
Publicado 2023

SARS-CoV-2 Inhibitors Identified by Phenotypic Analysis of a Collection of Viral RNA-Binding Molecules

por Simba-Lahuasi, Alvaro, Cantero-Camacho, Ángel, Rosales, Romel, McGovern, Briana Lynn, Rodríguez, M. Luis, Marchán, Vicente, White, Kris M., García-Sastre, Adolfo, Gallego, José
Publicado 2022

Epitope spreading driven by the joint action of CART cells and pharmacological STING stimulation counteracts tumor escape via antigen-loss variants

por Conde, Enrique, Vercher, Enric, Soria-Castellano, Marta, Suarez-Olmos, Jesús, Mancheño, Uxua, Elizalde, Edurne, Rodriguez, M Luis, Glez-Vaz, Javier, Casares, Noelia, Rodríguez-García, Estefanía, Hommel, Mirja, González-Aseguinolaza, Gloria, Uranga-Murillo, Iratxe, Pardo, Julian, Alkorta, Gorka, Melero, Ignacio, Lasarte, Juan, Hervas-Stubbs, Sandra
Publicado 2021

Preclinical and randomized phase I studies of plitidepsin in adults hospitalized with COVID-19

por Varona, Jose F, Landete, Pedro, Lopez-Martin, Jose A, Estrada, Vicente, Paredes, Roger, Guisado-Vasco, Pablo, Fernandez de Orueta, Lucia, Torralba, Miguel, Fortun, Jesus, Vates, Roberto, Barberan, Jose, Clotet, Bonaventura, Ancochea, Julio, Carnevali, Daniel, Cabello, Noemi, Porras, Lourdes, Gijon, Paloma, Monereo, Alfonso, Abad, Daniel, Zuñiga, Sonia, Sola, Isabel, Rodon, Jordi, Vergara-Alert, Julia, Izquierdo-Useros, Nuria, Fudio, Salvador, Pontes, Maria Jose, de Rivas, Beatriz, Giron de Velasco, Patricia, Nieto, Antonio, Gomez, Javier, Aviles, Pablo, Lubomirov, Rubin, Belgrano, Alvaro, Sopesen, Belen, White, Kris M, Rosales, Romel, Yildiz, Soner, Reuschl, Ann-Kathrin, Thorne, Lucy G, Jolly, Clare, Towers, Greg J, Zuliani-Alvarez, Lorena, Bouhaddou, Mehdi, Obernier, Kirsten, McGovern, Briana L, Rodriguez, M Luis, Enjuanes, Luis, Fernandez-Sousa, Jose M, Krogan, Nevan J, Jimeno, Jose M, Garcia-Sastre, Adolfo
Publicado 2022