MEG3 Expression Indicates Lymph Node Metastasis and Presence of Cancer-Associated Fibroblasts in Papillary Thyroid Cancer

por Dadafarin, Sina, Rodríguez, Tomás C., Carnazza, Michelle A., Tiwari, Raj K., Moscatello, Augustine, Geliebter, Jan
Publicado 2022

Self-inactivating, all-in-one AAV vectors for precision Cas9 genome editing via homology-directed repair in vivo

por Ibraheim, Raed, Tai, Phillip W. L., Mir, Aamir, Javeed, Nida, Wang, Jiaming, Rodríguez, Tomás C., Namkung, Suk, Nelson, Samantha, Khokhar, Eraj Shafiq, Mintzer, Esther, Maitland, Stacy, Chen, Zexiang, Cao, Yueying, Tsagkaraki, Emmanouela, Wolfe, Scot A., Wang, Dan, Pai, Athma A., Xue, Wen, Gao, Guangping, Sontheimer, Erik J.
Publicado 2021

PAM-flexible genome editing with an engineered chimeric Cas9

por Zhao, Lin, Koseki, Sabrina R. T., Silverstein, Rachel A., Amrani, Nadia, Peng, Christina, Kramme, Christian, Savic, Natasha, Pacesa, Martin, Rodríguez, Tomás C., Stan, Teodora, Tysinger, Emma, Hong, Lauren, Yudistyra, Vivian, Ponnapati, Manvitha R., Jacobson, Joseph M., Church, George M., Jakimo, Noah, Truant, Ray, Jinek, Martin, Kleinstiver, Benjamin P., Sontheimer, Erik J., Chatterjee, Pranam
Publicado 2023

Intratracheally administered LNA gapmer antisense oligonucleotides induce robust gene silencing in mouse lung fibroblasts

por Shin, Minwook, Chan, Io Long, Cao, Yuming, Gruntman, Alisha M, Lee, Jonathan, Sousa, Jacquelyn, Rodríguez, Tomás C, Echeverria, Dimas, Devi, Gitali, Debacker, Alexandre J, Moazami, Michael P, Krishnamurthy, Pranathi Meda, Rembetsy-Brown, Julia M, Kelly, Karen, Yukselen, Onur, Donnard, Elisa, Parsons, Teagan J, Khvorova, Anastasia, Sontheimer, Erik J, Maehr, René, Garber, Manuel, Watts, Jonathan K
Publicado 2022

CRISPR-enhanced human adipocyte browning as cell therapy for metabolic disease

por Tsagkaraki, Emmanouela, Nicoloro, Sarah M., DeSouza, Tiffany, Solivan-Rivera, Javier, Desai, Anand, Lifshitz, Lawrence M., Shen, Yuefei, Kelly, Mark, Guilherme, Adilson, Henriques, Felipe, Amrani, Nadia, Ibraheim, Raed, Rodriguez, Tomas C., Luk, Kevin, Maitland, Stacy, Friedline, Randall H., Tauer, Lauren, Hu, Xiaodi, Kim, Jason K., Wolfe, Scot A., Sontheimer, Erik J., Corvera, Silvia, Czech, Michael P.
Publicado 2021