In vivo CRISPR-Cas9 inhibition of hepatic LDH as treatment of primary hyperoxaluria

por Martinez-Turrillas, Rebeca, Martin-Mallo, Angel, Rodriguez-Diaz, Saray, Zapata-Linares, Natalia, Rodriguez-Marquez, Paula, San Martin-Uriz, Patxi, Vilas-Zornoza, Amaia, Calleja-Cervantes, María E., Salido, Eduardo, Prosper, Felipe, Rodriguez-Madoz, Juan R.
Publicado 2022

DENV Inhibits Type I IFN Production in Infected Cells by Cleaving Human STING

por Aguirre, Sebastian, Maestre, Ana M., Pagni, Sarah, Patel, Jenish R., Savage, Timothy, Gutman, Delia, Maringer, Kevin, Bernal-Rubio, Dabeiba, Shabman, Reed S., Simon, Viviana, Rodriguez-Madoz, Juan R., Mulder, Lubbertus C. F., Barber, Glen N., Fernandez-Sesma, Ana
Publicado 2012

CRISPR/Cas9-mediated glycolate oxidase disruption is an efficacious and safe treatment for primary hyperoxaluria type I

por Zabaleta, Nerea, Barberia, Miren, Martin-Higueras, Cristina, Zapata-Linares, Natalia, Betancor, Isabel, Rodriguez, Saray, Martinez-Turrillas, Rebeca, Torella, Laura, Vales, Africa, Olagüe, Cristina, Vilas-Zornoza, Amaia, Castro-Labrador, Laura, Lara-Astiaso, David, Prosper, Felipe, Salido, Eduardo, Gonzalez-Aseguinolaza, Gloria, Rodriguez-Madoz, Juan R.
Publicado 2018

Optimization of universal allogeneic CAR-T cells combining CRISPR and transposon-based technologies for treatment of acute myeloid leukemia

por Calviño, Cristina, Ceballos, Candela, Alfonso, Ana, Jauregui, Patricia, Calleja-Cervantes, Maria E., San Martin-Uriz, Patxi, Rodriguez-Marquez, Paula, Martin-Mallo, Angel, Iglesias, Elena, Abizanda, Gloria, Rodriguez-Diaz, Saray, Martinez-Turrillas, Rebeca, Illarramendi, Jorge, Viguria, Maria C., Redondo, Margarita, Rifon, Jose, Villar, Sara, Lasarte, Juan J., Inoges, Susana, Lopez-Diaz de Cerio, Ascension, Hernaez, Mikel, Prosper, Felipe, Rodriguez-Madoz, Juan R.
Publicado 2023

Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers

por Agirre, Xabier, Castellano, Giancarlo, Pascual, Marien, Heath, Simon, Kulis, Marta, Segura, Victor, Bergmann, Anke, Esteve, Anna, Merkel, Angelika, Raineri, Emanuele, Agueda, Lidia, Blanc, Julie, Richardson, David, Clarke, Laura, Datta, Avik, Russiñol, Nuria, Queirós, Ana C., Beekman, Renée, Rodríguez-Madoz, Juan R., José-Enériz, Edurne San, Fang, Fang, Gutiérrez, Norma C., García-Verdugo, José M., Robson, Michael I., Schirmer, Eric C., Guruceaga, Elisabeth, Martens, Joost H.A., Gut, Marta, Calasanz, Maria J., Flicek, Paul, Siebert, Reiner, Campo, Elías, Miguel, Jesús F. San, Melnick, Ari, Stunnenberg, Hendrik G., Gut, Ivo G., Prosper, Felipe, Martín-Subero, José I.
Publicado 2015

CAR density influences antitumoral efficacy of BCMA CAR T cells and correlates with clinical outcome

por Rodriguez-Marquez, Paula, Calleja-Cervantes, Maria E., Serrano, Guillermo, Oliver-Caldes, Aina, Palacios-Berraquero, Maria L., Martin-Mallo, Angel, Calviño, Cristina, Español-Rego, Marta, Ceballos, Candela, Lozano, Teresa, San Martin-Uriz, Patxi, Vilas-Zornoza, Amaia, Rodriguez-Diaz, Saray, Martinez-Turrillas, Rebeca, Jauregui, Patricia, Alignani, Diego, Viguria, Maria C., Redondo, Margarita, Pascal, Mariona, Martin-Antonio, Beatriz, Juan, Manel, Urbano-Ispizua, Alvaro, Rodriguez-Otero, Paula, Alfonso-Pierola, Ana, Paiva, Bruno, Lasarte, Juan J., Inoges, Susana, Lopez-Diaz de Cerio, Ascension, San-Miguel, Jesus, Fernandez de Larrea, Carlos, Hernaez, Mikel, Rodriguez-Madoz, Juan R., Prosper, Felipe
Publicado 2022

Progress and harmonization of gene editing to treat human diseases: Proceeding of COST Action CA21113 GenE-HumDi

por Cavazza, Alessia, Hendel, Ayal, Bak, Rasmus O., Rio, Paula, Güell, Marc, Lainšček, Duško, Arechavala-Gomeza, Virginia, Peng, Ling, Hapil, Fatma Zehra, Harvey, Joshua, Ortega, Francisco G., Gonzalez-Martinez, Coral, Lederer, Carsten W., Mikkelsen, Kasper, Gasiunas, Giedrius, Kalter, Nechama, Gonçalves, Manuel A.F.V., Petersen, Julie, Garanto, Alejandro, Montoliu, Lluis, Maresca, Marcello, Seemann, Stefan E., Gorodkin, Jan, Mazini, Loubna, Sanchez, Rosario, Rodriguez-Madoz, Juan R., Maldonado-Pérez, Noelia, Laura, Torella, Schmueck-Henneresse, Michael, Maccalli, Cristina, Grünewald, Julian, Carmona, Gloria, Kachamakova-Trojanowska, Neli, Miccio, Annarita, Martin, Francisco, Turchiano, Giandomenico, Cathomen, Toni, Luo, Yonglun, Tsai, Shengdar Q., Benabdellah, Karim
Publicado 2023

Chromatin activation as a unifying principle underlying pathogenic mechanisms in multiple myeloma

por Ordoñez, Raquel, Kulis, Marta, Russiñol, Nuria, Chapaprieta, Vicente, Carrasco-Leon, Arantxa, García-Torre, Beatriz, Charalampopoulou, Stella, Clot, Guillem, Beekman, Renée, Meydan, Cem, Duran-Ferrer, Martí, Verdaguer-Dot, Núria, Vilarrasa-Blasi, Roser, Soler-Vila, Paula, Garate, Leire, Miranda, Estíbaliz, San José-Enériz, Edurne, Rodriguez-Madoz, Juan R., Ezponda, Teresa, Martínez-Turrilas, Rebeca, Vilas-Zornoza, Amaia, Lara-Astiaso, David, Dupéré-Richer, Daphné, Martens, Joost H.A., El-Omri, Halima, Taha, Ruba Y., Calasanz, Maria J., Paiva, Bruno, San Miguel, Jesus, Flicek, Paul, Gut, Ivo, Melnick, Ari, Mitsiades, Constantine S., Licht, Jonathan D., Campo, Elias, Stunnenberg, Hendrik G., Agirre, Xabier, Prosper, Felipe, Martin-Subero, Jose I.
Publicado 2020