Small Molecule-Based Enzyme Inhibitors in the Treatment of Primary Hyperoxalurias

por Moya-Garzon, Maria Dolores, Gomez-Vidal, Jose Antonio, Alejo-Armijo, Alfonso, Altarejos, Joaquin, Rodriguez-Madoz, Juan Roberto, Fernandes, Miguel Xavier, Salido, Eduardo, Salido, Sofia, Diaz-Gavilan, Monica
Publicado 2021

SimiC enables the inference of complex gene regulatory dynamics across cell phenotypes

por Peng, Jianhao, Serrano, Guillermo, Traniello, Ian M., Calleja-Cervantes, Maria E., Chembazhi, Ullas V., Bangru, Sushant, Ezponda, Teresa, Rodriguez-Madoz, Juan Roberto, Kalsotra, Auinash, Prosper, Felipe, Ochoa, Idoia, Hernaez, Mikel
Publicado 2022

Reversible dual inhibitor against G9a and DNMT1 improves human iPSC derivation enhancing MET and facilitating transcription factor engagement to the genome

por Rodriguez-Madoz, Juan Roberto, San Jose-Eneriz, Edurne, Rabal, Obdulia, Zapata-Linares, Natalia, Miranda, Estibaliz, Rodriguez, Saray, Porciuncula, Angelo, Vilas-Zornoza, Amaia, Garate, Leire, Segura, Victor, Guruceaga, Elizabeth, Agirre, Xabier, Oyarzabal, Julen, Prosper, Felipe
Publicado 2017

Overcoming T cell dysfunction in acidic pH to enhance adoptive T cell transfer immunotherapy

por Navarro, Flor, Casares, Noelia, Martín-Otal, Celia, Lasarte-Cía, Aritz, Gorraiz, Marta, Sarrión, Patricia, Llopiz, Diana, Reparaz, David, Varo, Nerea, Rodriguez-Madoz, Juan Roberto, Prosper, Felipe, Hervás-Stubbs, Sandra, Lozano, Teresa, Lasarte, Juan José
Publicado 2022

Revealing cell populations catching the early stages of human embryo development in naive pluripotent stem cell cultures

por Moya-Jódar, Marta, Ullate-Agote, Asier, Barlabé, Paula, Rodríguez-Madoz, Juan Roberto, Abizanda, Gloria, Barreda, Carolina, Carvajal-Vergara, Xonia, Vilas-Zornoza, Amaia, Romero, Juan Pablo, Garate, Leire, Agirre, Xabier, Coppiello, Giulia, Prósper, Felipe, Aranguren, Xabier L.
Publicado 2022

Long-Term PEDF Release in Rat Iris and Retinal Epithelial Cells after Sleeping Beauty Transposon-Mediated Gene Delivery

por Garcia-Garcia, Laura, Recalde, Sergio, Hernandez, Maria, Bezunartea, Jaione, Rodriguez-Madoz, Juan Roberto, Johnen, Sandra, Diarra, Sabine, Marie, Corinne, Izsvák, Zsuzsanna, Ivics, Zoltán, Scherman, Daniel, Kropp, Martina, Thumann, Gabriele, Prosper, Felipe, Fernandez-Robredo, Patricia, Garcia-Layana, Alfredo
Publicado 2017

Preclinical Evaluation of a Cell-Based Gene Therapy Using the Sleeping Beauty Transposon System in Choroidal Neovascularization

por Hernandez, Maria, Recalde, Sergio, Garcia-Garcia, Laura, Bezunartea, Jaione, Miskey, Csaba, Johnen, Sandra, Diarra, Sabine, Sebe, Attila, Rodriguez-Madoz, Juan Roberto, Pouillot, Severine, Marie, Corinne, Izsvák, Zsuzsanna, Scherman, Daniel, Kropp, Martina, Prosper, Felipe, Thumann, Gabriele, Ivics, Zoltán, Garcia-Layana, Alfredo, Fernandez-Robredo, Patricia
Publicado 2019

Generation of NKX2.5(GFP) Reporter Human iPSCs and Differentiation Into Functional Cardiac Fibroblasts

por López-Muneta, Leyre, Linares, Javier, Casis, Oscar, Martínez-Ibáñez, Laura, González Miqueo, Arantxa, Bezunartea, Jaione, Sanchez de la Nava, Ana Maria, Gallego, Mónica, Fernández-Santos, María Eugenia, Rodriguez-Madoz, Juan Roberto, Aranguren, Xabier L., Fernández-Avilés, Francisco, Segovia, José Carlos, Prósper, Felipe, Carvajal-Vergara, Xonia
Publicado 2022

One-Step In Vitro Generation of ETV2-Null Pig Embryos

por Moya-Jódar, Marta, Coppiello, Giulia, Rodríguez-Madoz, Juan Roberto, Abizanda, Gloria, Barlabé, Paula, Vilas-Zornoza, Amaia, Ullate-Agote, Asier, Luongo, Chiara, Rodríguez-Tobón, Ernesto, Navarro-Serna, Sergio, París-Oller, Evelyne, Oficialdegui, Maria, Carvajal-Vergara, Xonia, Ordovás, Laura, Prósper, Felipe, García-Vázquez, Francisco Alberto, Aranguren, Xabier L.
Publicado 2022

Targeting the extra domain A of fibronectin for cancer therapy with CAR-T cells

por Martín-Otal, Celia, Lasarte-Cia, Aritz, Serrano, Diego, Casares, Noelia, Conde, Enrique, Navarro, Flor, Sánchez-Moreno, Inés, Gorraiz, Marta, Sarrión, Patricia, Calvo, Alfonso, De Andrea, Carlos E, Echeveste, José, Vilas, Amaia, Rodriguez-Madoz, Juan Roberto, San Miguel, Jesús, Prosper, Felipe, Hervas-Stubbs, Sandra, Lasarte, Juan Jose, Lozano, Teresa
Publicado 2022

Time 2EVOLVE: predicting efficacy of engineered T-cells – how far is the bench from the bedside?

por Guedan, Sonia, Luu, Maik, Ammar, Delphine, Barbao, Paula, Bonini, Chiara, Bousso, Philippe, Buchholz, Christian J, Casucci, Monica, De Angelis, Biagio, Donnadieu, Emmanuel, Espie, David, Greco, Beatrice, Groen, Richard, Huppa, Johannes B, Kantari-Mimoun, Chahrazade, Laugel, Bruno, Mantock, Mary, Markman, Janet L, Morris, Emma, Quintarelli, Concetta, Rade, Michael, Reiche, Kristin, Rodriguez-Garcia, Alba, Rodriguez-Madoz, Juan Roberto, Ruggiero, Eliana, Themeli, Maria, Hudecek, Michael, Marchiq, Ibtissam
Publicado 2022

Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs in hematological malignancies

por San José-Enériz, Edurne, Agirre, Xabier, Rabal, Obdulia, Vilas-Zornoza, Amaia, Sanchez-Arias, Juan A., Miranda, Estibaliz, Ugarte, Ana, Roa, Sergio, Paiva, Bruno, Estella-Hermoso de Mendoza, Ander, Alvarez, Rosa María, Casares, Noelia, Segura, Victor, Martín-Subero, José I., Ogi, François-Xavier, Soule, Pierre, Santiveri, Clara M., Campos-Olivas, Ramón, Castellano, Giancarlo, de Barrena, Maite Garcia Fernandez, Rodriguez-Madoz, Juan Roberto, García-Barchino, Maria José, Lasarte, Juan Jose, Avila, Matias A, Martinez-Climent, Jose Angel, Oyarzabal, Julen, Prosper, Felipe
Publicado 2017