CRISPR-Cas9: A Revolutionary Tool for Cancer Modelling

por Torres-Ruiz, Raul, Rodriguez-Perales, Sandra
Publicado 2015

CRISPR/Cas9 for Cancer Therapy: Hopes and Challenges

por Martinez-Lage, Marta, Puig-Serra, Pilar, Menendez, Pablo, Torres-Ruiz, Raul, Rodriguez-Perales, Sandra
Publicado 2018

Functional characterization of two enhancers located downstream FOXP2

por Torres-Ruiz, Raúl, Benítez-Burraco, Antonio, Martínez-Lage, Marta, Rodríguez-Perales, Sandra, García-Bellido, Paloma
Publicado 2019

Detection of chromosome instability by interphase FISH in mouse and human tissues

por Torres-Ruiz, Raul, Grazioso, Tatiana P., Brandt, Marta, Martinez-Lage, Marta, Rodriguez-Perales, Sandra, Djouder, Nabil
Publicado 2021

Functional Characterization of a Dual Enhancer/Promoter Regulatory Element Leading Human CD69 Expression

por Redondo-Antón, Jennifer, Fontela, MG, Notario, Laura, Torres-Ruiz, Raúl, Rodríguez-Perales, Sandra, Lorente, Elena, Lauzurica, Pilar
Publicado 2020

Fast Diffusion Sustains Plasma Membrane Accumulation of Phosphatase of Regenerating Liver-1

por Castro-Sánchez, Patricia, Hernández-Pérez, Sara, Aguilar-Sopeña, Oscar, Ramírez-Muñoz, Rocia, Rodríguez-Perales, Sandra, Torres-Ruiz, Raúl, Roda-Navarro, Pedro
Publicado 2020

Narrowing the Genetic Causes of Language Dysfunction in the 1q21.1 Microduplication Syndrome

por Benítez-Burraco, Antonio, Barcos-Martínez, Montserrat, Espejo-Portero, Isabel, Fernández-Urquiza, Maite, Torres-Ruiz, Raúl, Rodríguez-Perales, Sandra, Jiménez-Romero, Ma Salud
Publicado 2018

CRISPR Approaches for the Diagnosis of Human Diseases

por Puig-Serra, Pilar, Casado-Rosas, Maria Cruz, Martinez-Lage, Marta, Olalla-Sastre, Beatriz, Alonso-Yanez, Alejandro, Torres-Ruiz, Raul, Rodriguez-Perales, Sandra
Publicado 2022

Somatic genome editing with the RCAS-TVA-CRISPR-Cas9 system for precision tumor modeling

por Oldrini, Barbara, Curiel-García, Álvaro, Marques, Carolina, Matia, Veronica, Uluçkan, Özge, Graña-Castro, Osvaldo, Torres-Ruiz, Raul, Rodriguez-Perales, Sandra, Huse, Jason T., Squatrito, Massimo
Publicado 2018

Efficient Recreation of t(11;22) EWSR1-FLI1(+) in Human Stem Cells Using CRISPR/Cas9

por Torres-Ruiz, Raul, Martinez-Lage, Marta, Martin, Maria C., Garcia, Aida, Bueno, Clara, Castaño, Julio, Ramirez, Juan C., Menendez, Pablo, Cigudosa, Juan C., Rodriguez-Perales, Sandra
Publicado 2017

Generation and characterization of a human iPSC cell line expressing inducible Cas9 in the “safe harbor” AAVS1 locus

por Castaño, Julio, Bueno, Clara, Jiménez-Delgado, Senda, Roca-Ho, Heleia, Fraga, Mario F., Fernandez, Agustín F., Nakanishi, Mahito, Torres-Ruiz, Raúl, Rodríguez-Perales, Sandra, Menéndez, Pablo
Publicado 2017

RIAM-VASP Module Relays Integrin Complement Receptors in Outside-In Signaling Driving Particle Engulfment

por Torres-Gomez, Alvaro, Sanchez-Trincado, Jose Luis, Toribio, Víctor, Torres-Ruiz, Raul, Rodríguez-Perales, Sandra, Yáñez-Mó, María, Reche, Pedro A., Cabañas, Carlos, Lafuente, Esther M.
Publicado 2020

OGG1 Inhibition Triggers Synthetic Lethality and Enhances The Effect of PARP Inhibitor Olaparib in BRCA1-Deficient TNBC Cells

por Baquero, Juan Miguel, Marchena-Perea, Erik, Mirabet, Rocío, Torres-Ruiz, Raúl, Blanco-Aparicio, Carmen, Rodríguez-Perales, Sandra, Helleday, Thomas, Benítez-Buelga, Carlos, Benítez, Javier, Osorio, Ana
Publicado 2022

Alterations in SLC4A2, SLC26A7 and SLC26A9 Drive Acid–Base Imbalance in Gastric Neuroendocrine Tumors and Uncover a Novel Mechanism for a Co-Occurring Polyautoimmune Scenario

por Calvete, Oriol, Reyes, José, Valdés-Socin, Hernán, Martin, Paloma, Marazuela, Mónica, Barroso, Alicia, Escalada, Javier, Castells, Antoni, Torres-Ruiz, Raúl, Rodríguez-Perales, Sandra, Currás-Freixes, María, Benítez, Javier
Publicado 2021

TALEN mediated gene editing in a mouse model of Fanconi anemia

por Pino-Barrio, Maria José, Giménez, Yari, Villanueva, Mariela, Hildenbeutel, Marcus, Sánchez-Dominguez, Rebeca, Rodríguez-Perales, Sandra, Pujol, Roser, Surrallés, Jordi, Río, Paula, Cathomen, Toni, Mussolino, Claudio, Bueren, Juan Antonio, Navarro, Susana
Publicado 2020

Therapeutic gene editing in CD34(+) hematopoietic progenitors from Fanconi anemia patients

por Diez, Begoña, Genovese, Pietro, Roman‐Rodriguez, Francisco J, Alvarez, Lara, Schiroli, Giulia, Ugalde, Laura, Rodriguez‐Perales, Sandra, Sevilla, Julian, Diaz de Heredia, Cristina, Holmes, Michael C, Lombardo, Angelo, Naldini, Luigi, Bueren, Juan Antonio, Rio, Paula
Publicado 2017

Robustness of Catalytically Dead Cas9 Activators in Human Pluripotent and Mesenchymal Stem Cells

por Petazzi, Paolo, Torres-Ruiz, Raul, Fidanza, Antonella, Roca-Ho, Heleia, Gutierrez-Agüera, Francisco, Castaño, Julio, Rodriguez-Perales, Sandra, Díaz de la Guardia, Rafael, López-Millán, Belén, Bigas, Anna, Forrester, Lesley M., Bueno, Clara, Menéndez, Pablo
Publicado 2020

Small molecule inhibitor of OGG1 blocks oxidative DNA damage repair at telomeres and potentiates methotrexate anticancer effects

por Baquero, Juan Miguel, Benítez-Buelga, Carlos, Rajagopal, Varshni, Zhenjun, Zhao, Torres-Ruiz, Raúl, Müller, Sarah, Hanna, Bishoy M. F., Loseva, Olga, Wallner, Olov, Michel, Maurice, Rodríguez-Perales, Sandra, Gad, Helge, Visnes, Torkild, Helleday, Thomas, Benítez, Javier, Osorio, Ana
Publicado 2021

Biallelic germline mutations in MAD1L1 induce a syndrome of aneuploidy with high tumor susceptibility

por Villarroya-Beltri, Carolina, Osorio, Ana, Torres-Ruiz, Raúl, Gómez-Sánchez, David, Trakala, Marianna, Sánchez-Belmonte, Agustin, Mercadillo, Fátima, Hurtado, Begoña, Pitarch, Borja, Hernández-Núñez, Almudena, Gómez-Caturla, Antonio, Rueda, Daniel, Perea, José, Rodríguez-Perales, Sandra, Malumbres, Marcos, Urioste, Miguel
Publicado 2022

The IS2 Element Improves Transcription Efficiency of Integration-Deficient Lentiviral Vector Episomes

por Sánchez-Hernández, Sabina, Gutierrez-Guerrero, Alejandra, Martín-Guerra, Rocío, Cortijo-Gutierrez, Marina, Tristán-Manzano, María, Rodriguez-Perales, Sandra, Sanchez, Laura, Garcia-Perez, Jose Luis, Chato-Astrain, Jesus, Fernandez-Valades, Ricardo, Carrillo-Galvez, Ana Belén, Anderson, Per, Montes, Rosa, Real, Pedro J., Martin, Francisco, Benabdellah, Karim
Publicado 2018