Enhancement of the Seed-Target Recognition Step in RNA Silencing by a PIWI/MID Domain Protein

por Parker, James S., Parizotto, Eneida A., Wang, Muhan, Roe, S. Mark, Barford, David
Publicado 2009

Tah1 helix-swap dimerization prevents mixed Hsp90 co-chaperone complexes

por Morgan, Rhodri M. L., Pal, Mohinder, Roe, S. Mark, Pearl, Laurence H., Prodromou, Chrisostomos
Publicado 2015

The structure of FKBP38 in complex with the MEEVD tetratricopeptide binding-motif of Hsp90

por Blundell, Katie L. I. M., Pal, Mohinder, Roe, S. Mark, Pearl, Laurence H., Prodromou, Chrisostomos
Publicado 2017

The X-ray structure of human calbindin-D28K: an improved model

por Noble, James W., Almalki, Rehab, Roe, S. Mark, Wagner, Armin, Duman, Ramona, Atack, John R.
Publicado 2018

Co-Crystalization and In Vitro Biological Characterization of 5-Aryl-4-(5-Substituted-2-4-Dihydroxyphenyl)-1,2,3-Thiadiazole Hsp90 Inhibitors

por Sharp, Swee Y., Roe, S. Mark, Kazlauskas, Egidijus, Čikotienė, Inga, Workman, Paul, Matulis, Daumantas, Prodromou, Chrisostomos
Publicado 2012

Trimerisation of carbon suboxide at a di-titanium centre to form a pyrone ring system

por Tsoureas, Nikolaos, Green, Jennifer C., Cloke, F. Geoffrey N., Puschmann, Horst, Roe, S. Mark, Tizzard, Graham
Publicado 2018

The Crystal Structure of the Hsp90-LA1011 Complex and the Mechanism by Which LA1011 May Improve the Prognosis of Alzheimer’s Disease

por Roe, S. Mark, Török, Zsolt, McGown, Andrew, Horváth, Ibolya, Spencer, John, Pázmány, Tamás, Vigh, László, Prodromou, Chrisostomos
Publicado 2023

Structure of the TPR Domain of AIP: Lack of Client Protein Interaction with the C-Terminal α-7 Helix of the TPR Domain of AIP Is Sufficient for Pituitary Adenoma Predisposition

por Morgan, Rhodri M. L., Hernández-Ramírez, Laura C., Trivellin, Giampaolo, Zhou, Lihong, Roe, S. Mark, Korbonits, Márta, Prodromou, Chrisostomos
Publicado 2012

Structure of an archaeal PCNA1–PCNA2–FEN1 complex: elucidating PCNA subunit and client enzyme specificity

por Doré, Andrew S., Kilkenny, Mairi L., Jones, Sarah A., Oliver, Antony W., Roe, S. Mark, Bell, Stephen D., Pearl, Laurence H.
Publicado 2006

Synthesis of a Thiazole Library via an Iridium-Catalyzed Sulfur Ylide Insertion Reaction

por Hassell-Hart, Storm, Speranzini, Elisa, Srikwanjai, Sirihathai, Hossack, Euan, Roe, S. Mark, Fearon, Daren, Akinbosede, Daniel, Hare, Stephen, Spencer, John
Publicado 2022

Structural Basis for Phosphorylation-Dependent Recruitment of Tel2 to Hsp90 by Pih1

por Pal, Mohinder, Morgan, Marc, Phelps, Sarah E.L., Roe, S. Mark, Parry-Morris, Sarah, Downs, Jessica A., Polier, Sigrun, Pearl, Laurence H., Prodromou, Chrisostomos
Publicado 2014

RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex

por Martino, Fabrizio, Pal, Mohinder, Muñoz-Hernández, Hugo, Rodríguez, Carlos F., Núñez-Ramírez, Rafael, Gil-Carton, David, Degliesposti, Gianluca, Skehel, J. Mark, Roe, S. Mark, Prodromou, Chrisostomos, Pearl, Laurence H., Llorca, Oscar
Publicado 2018

Author Correction: RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex

por Martino, Fabrizio, Pal, Mohinder, Muñoz-Hernández, Hugo, Rodríguez, Carlos F., Núñez-Ramírez, Rafael, Gil-Carton, David, Degliesposti, Gianluca, Skehel, J. Mark, Roe, S. Mark, Prodromou, Chrisostomos, Pearl, Laurence H., Llorca, Oscar
Publicado 2018

Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein

por Chen, Xiangrong, Ali, Yusuf I, Fisher, Charlotte EL, Arribas-Bosacoma, Raquel, Rajasekaran, Mohan B, Williams, Gareth, Walker, Sarah, Booth, Jessica R, Hudson, Jessica JR, Roe, S Mark, Pearl, Laurence H, Ward, Simon E, Pearl, Frances MG, Oliver, Antony W
Publicado 2021

The structure-function relationship of oncogenic LMTK3

por Ditsiou, Angeliki, Cilibrasi, Chiara, Simigdala, Nikiana, Papakyriakou, Athanasios, Milton-Harris, Leanne, Vella, Viviana, Nettleship, Joanne E., Lo, Jae Ho, Soni, Shivani, Smbatyan, Goar, Ntavelou, Panagiota, Gagliano, Teresa, Iachini, Maria Chiara, Khurshid, Sahir, Simon, Thomas, Zhou, Lihong, Hassell-Hart, Storm, Carter, Philip, Pearl, Laurence H., Owen, Robin L., Owens, Raymond J., Roe, S. Mark, Chayen, Naomi E., Lenz, Heinz-Josef, Spencer, John, Prodromou, Chrisostomos, Klinakis, Apostolos, Stebbing, Justin, Giamas, Georgios
Publicado 2020