Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria

por Wirawan, E, Vande Walle, L, Kersse, K, Cornelis, S, Claerhout, S, Vanoverberghe, I, Roelandt, R, De Rycke, R, Verspurten, J, Declercq, W, Agostinis, P, Vanden Berghe, T, Lippens, S, Vandenabeele, P
Publicado 2010

Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis

por Remijsen, Q, Goossens, V, Grootjans, S, Van den Haute, C, Vanlangenakker, N, Dondelinger, Y, Roelandt, R, Bruggeman, I, Goncalves, A, Bertrand, M J M, Baekelandt, V, Takahashi, N, Berghe, T V, Vandenabeele, P
Publicado 2014

Simultaneous targeting of interleukin-1 and interleukin-18 is required for protection against inflammatory and septic shock

por Berghe, T Vanden, Demon, D, Bogaert, P, Vandendriessche, B, Goethals, A, Depuydt, B, Vuylsteke, M, Roelandt, R, Van Wonterghem, E, Vandenbroecke, J, Choi, SM, Meyer, E, Krautwald, S, Declercq, W, Takahashi, N, Cauwels, A, Vandenabeele, P
Publicado 2014

Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models

por Takahashi, N, Duprez, L, Grootjans, S, Cauwels, A, Nerinckx, W, DuHadaway, J B, Goossens, V, Roelandt, R, Van Hauwermeiren, F, Libert, C, Declercq, W, Callewaert, N, Prendergast, G C, Degterev, A, Yuan, J, Vandenabeele, P
Publicado 2012