Mathematical Model of a Telomerase Transcriptional Regulatory Network Developed by Cell-Based Screening: Analysis of Inhibitor Effects and Telomerase Expression Mechanisms

por Bilsland, Alan E., Stevenson, Katrina, Liu, Yu, Hoare, Stacey, Cairney, Claire J., Roffey, Jon, Keith, W. Nicol
Publicado 2014

A Novel Pyrazolopyrimidine Ligand of Human PGK1 and Stress Sensor DJ1 Modulates the Shelterin Complex and Telomere Length Regulation

por Bilsland, Alan E., Liu, Yu, Turnbull, Andrew, Sumpton, David, Stevenson, Katrina, Cairney, Claire J., Boyd, Susan M., Roffey, Jon, Jenkinson, David, Keith, W. Nicol
Publicado 2019

Dynamic Telomerase Gene Suppression via Network Effects of GSK3 Inhibition

por Bilsland, Alan E., Hoare, Stacey, Stevenson, Katrina, Plumb, Jane, Gomez-Roman, Natividad, Cairney, Claire, Burns, Sharon, Lafferty-Whyte, Kyle, Roffey, Jon, Hammonds, Tim, Keith, W. Nicol
Publicado 2009

Scoring of senescence signalling in multiple human tumour gene expression datasets, identification of a correlation between senescence score and drug toxicity in the NCI60 panel an...

por Lafferty-Whyte, Kyle, Bilsland, Alan, Cairney, Claire J, Hanley, Lorna, Jamieson, Nigel B, Zaffaroni, Nadia, Oien, Karin A, Burns, Sharon, Roffey, Jon, Boyd, Susan M, Keith, W Nicol
Publicado 2010

aPKC Cycles between Functionally Distinct PAR Protein Assemblies to Drive Cell Polarity

por Rodriguez, Josana, Peglion, Florent, Martin, Jack, Hubatsch, Lars, Reich, Jacob, Hirani, Nisha, Gubieda, Alicia G., Roffey, Jon, Fernandes, Artur Ribeiro, St Johnston, Daniel, Ahringer, Julie, Goehring, Nathan W.
Publicado 2017

Regulation of polarized morphogenesis by protein kinase C iota in oncogenic epithelial spheroids

por Linch, Mark, Sanz-Garcia, Marta, Rosse, Carine, Riou, Philippe, Peel, Nick, Madsen, Chris D., Sahai, Erik, Downward, Julian, Khwaja, Asim, Dillon, Christian, Roffey, Jon, Cameron, Angus J.M., Parker, Peter J.
Publicado 2014