Human inhibitory leukocyte Ig-like receptors: from immunotolerance to immunotherapy

por De Louche, Calvin D., Roghanian, Ali
Publicado 2022

Towards a better understanding of human iNKT cell subpopulations for improved clinical outcomes

por Look, Alex, Burns, Daniel, Tews, Ivo, Roghanian, Ali, Mansour, Salah
Publicado 2023

Human leukocyte immunoglobulin-like receptors in health and disease

por Redondo-García, Silvia, Barritt, Christopher, Papagregoriou, Charys, Yeboah, Muchaala, Frendeus, Björn, Cragg, Mark S., Roghanian, Ali
Publicado 2023

LILRB3 (ILT5) is a myeloid cell checkpoint that elicits profound immunomodulation

por Yeboah, Muchaala, Papagregoriou, Charys, Jones, Des C., Chan, H.T. Claude, Hu, Guangan, McPartlan, Justine S., Schiött, Torbjörn, Mattson, Ulrika, Mockridge, C. Ian, Tornberg, Ulla-Carin, Hambe, Björn, Ljungars, Anne, Mattsson, Mikael, Tews, Ivo, Glennie, Martin J., Thirdborough, Stephen M., Trowsdale, John, Frendeus, Björn, Chen, Jianzhu, Cragg, Mark S., Roghanian, Ali
Publicado 2020

FcγRIIB controls antibody-mediated target cell depletion by ITIM-independent mechanisms

por Simpson, Alexander P., Roghanian, Ali, Oldham, Robert J., Chan, H.T. Claude, Penfold, Christine A., Kim, Hyung J., Inzhelevskaya, Tatyana, Mockridge, C. Ian, Cox, Kerry L., Bogdanov, Yury D., James, Sonya, Tutt, Alison L., Rycroft, Daniel, Morley, Peter, Dahal, Lekh N., Teige, Ingrid, Frendeus, Björn, Beers, Stephen A., Cragg, Mark S.
Publicado 2022

Conformation of the Human Immunoglobulin G2 Hinge Imparts Superagonistic Properties to Immunostimulatory Anticancer Antibodies

por White, Ann L., Chan, H.T. Claude, French, Ruth R., Willoughby, Jane, Mockridge, C. Ian, Roghanian, Ali, Penfold, Christine A., Booth, Steven G., Dodhy, Ali, Polak, Marta E., Potter, Elizabeth A., Ardern-Jones, Michael R., Verbeek, J. Sjef, Johnson, Peter W.M., Al-Shamkhani, Aymen, Cragg, Mark S., Beers, Stephen A., Glennie, Martin J.
Publicado 2015

In vivo genome editing and organoid transplantation models of colorectal cancer

por Roper, Jatin, Tammela, Tuomas, Cetinbas, Naniye Malli, Akkad, Adam, Roghanian, Ali, Rickelt, Steffen, Almeqdadi, Mohammad, Wu, Katherine, Oberli, Matthias, Sánchez-Rivera, Francisco, Park, Yoona, Liang, Xu, Eng, George, Taylor, Martin S., Azimi, Roxana, Kedrin, Dmitriy, Neupane, Rachit, Beyaz, Semir, Sicinska, Ewa T., Suarez, Yvelisse, Yoo, James, Chen, Lillian, Zukerberg, Lawrence, Katajisto, Pekka, Deshpande, Vikram, Bass, Adam, Tsichlis, Philip N., Lees, Jacqueline, Langer, Robert, Hynes, Richard O., Chen, Jianzhu, Bhutkar, Arjun J., Jacks, Tyler, Yilmaz, Ömer H.
Publicado 2017

HIF activation enhances FcγRIIb expression on mononuclear phagocytes impeding tumor targeting antibody immunotherapy

por Hussain, Khiyam, Liu, Rena, Smith, Rosanna C. G., Müller, Kri T. J., Ghorbani, Mohammadmersad, Macari, Sofia, Cleary, Kirstie L. S., Oldham, Robert J., Foxall, Russell B., James, Sonya, Booth, Steven G., Murray, Tom, Dahal, Lekh N., Hargreaves, Chantal E., Kemp, Robert S., Longley, Jemma, Douglas, James, Markham, Hannah, Chee, Serena J., Stopforth, Richard J., Roghanian, Ali, Carter, Matthew J., Ottensmeier, Christian H., Frendéus, Bjorn, Cutress, Ramsey I., French, Ruth R., Glennie, Martin J., Strefford, Jonathan C., Thirdborough, Stephen M., Beers, Stephen A., Cragg, Mark S.
Publicado 2022