cisTEM, user-friendly software for single-particle image processing

por Grant, Timothy, Rohou, Alexis, Grigorieff, Nikolaus
Publicado 2018

Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM

por Zhou, Anna, Rohou, Alexis, Schep, Daniel G, Bason, John V, Montgomery, Martin G, Walker, John E, Grigorieff, Nikolaus, Rubinstein, John L
Publicado 2015

Structures of autoinhibited and polymerized forms of CARD9 reveal mechanisms of CARD9 and CARD11 activation

por Holliday, Michael J., Witt, Axel, Rodríguez Gama, Alejandro, Walters, Benjamin T., Arthur, Christopher P., Halfmann, Randal, Rohou, Alexis, Dueber, Erin C., Fairbrother, Wayne J.
Publicado 2019

Allosteric inhibition of HTRA1 activity by a conformational lock mechanism to treat age-related macular degeneration

por Gerhardy, Stefan, Ultsch, Mark, Tang, Wanjian, Green, Evan, Holden, Jeffrey K., Li, Wei, Estevez, Alberto, Arthur, Chris, Tom, Irene, Rohou, Alexis, Kirchhofer, Daniel
Publicado 2022

Structural basis for HCMV Pentamer receptor recognition and antibody neutralization

por Kschonsak, Marc, Johnson, Matthew C., Schelling, Rachel, Green, Evan M., Rougé, Lionel, Ho, Hoangdung, Patel, Nidhi, Kilic, Cem, Kraft, Edward, Arthur, Christopher P., Rohou, Alexis L., Comps-Agrar, Laetitia, Martinez-Martin, Nadia, Perez, Laurent, Payandeh, Jian, Ciferri, Claudio
Publicado 2022

Cryo-EM reveals an unprecedented binding site for Na(V)1.7 inhibitors enabling rational design of potent hybrid inhibitors

por Kschonsak, Marc, Jao, Christine C, Arthur, Christopher P, Rohou, Alexis L, Bergeron, Philippe, Ortwine, Daniel F, McKerrall, Steven J, Hackos, David H, Deng, Lunbin, Chen, Jun, Li, Tianbo, Dragovich, Peter S, Volgraf, Matthew, Wright, Matthew R, Payandeh, Jian, Ciferri, Claudio, Tellis, John C
Publicado 2023

A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatment

por Balestrini, Alessia, Joseph, Victory, Dourado, Michelle, Reese, Rebecca M., Shields, Shannon D., Rougé, Lionel, Bravo, Daniel D., Chernov-Rogan, Tania, Austin, Cary D., Chen, Huifen, Wang, Lan, Villemure, Elisia, Shore, Daniel G.M., Verma, Vishal A., Hu, Baihua, Chen, Yong, Leong, Laurie, Bjornson, Chris, Hötzel, Kathy, Gogineni, Alvin, Lee, Wyne P., Suto, Eric, Wu, Xiumin, Liu, John, Zhang, Juan, Gandham, Vineela, Wang, Jianyong, Payandeh, Jian, Ciferri, Claudio, Estevez, Alberto, Arthur, Christopher P., Kortmann, Jens, Wong, Ryan L., Heredia, Jose E., Doerr, Jonas, Jung, Min, Vander Heiden, Jason A., Roose-Girma, Merone, Tam, Lucinda, Barck, Kai H., Carano, Richard A.D., Ding, Han Ting, Brillantes, Bobby, Tam, Christine, Yang, Xiaoying, Gao, Simon S., Ly, Justin Q., Liu, Liling, Chen, Liuxi, Liederer, Bianca M., Lin, Joseph H., Magnuson, Steven, Chen, Jun, Hackos, David H., Elstrott, Justin, Rohou, Alexis, Safina, Brian S., Volgraf, Matthew, Bauer, Rebecca N., Riol-Blanco, Lorena
Publicado 2021