Development of a CRISPR/Cas9-based therapy for Hutchinson-Gilford progeria syndrome

por Santiago-Fernández, Olaya, Osorio, Fernando G., Quesada, Víctor, Rodríguez, Francisco, Basso, Sammy, Maeso, Daniel, Rolas, Loïc, Barkaway, Anna, Nourshargh, Sussan, Folgueras, Alicia R., Freije, José M. P., López-Otín, Carlos
Publicado 2019

Local microvascular leakage promotes trafficking of activated neutrophils to remote organs

por Owen-Woods, Charlotte, Joulia, Régis, Barkaway, Anna, Rolas, Loïc, Ma, Bin, Nottebaum, Astrid Fee, Arkill, Kenton P., Stein, Monja, Girbl, Tamara, Golding, Matthew, Bates, David O., Vestweber, Dietmar, Voisin, Mathieu-Benoit, Nourshargh, Sussan
Publicado 2020

Distinct Compartmentalization of the Chemokines CXCL1 and CXCL2 and the Atypical Receptor ACKR1 Determine Discrete Stages of Neutrophil Diapedesis

por Girbl, Tamara, Lenn, Tchern, Perez, Lorena, Rolas, Loïc, Barkaway, Anna, Thiriot, Aude, del Fresno, Carlos, Lynam, Eleanor, Hub, Elin, Thelen, Marcus, Graham, Gerard, Alon, Ronen, Sancho, David, von Andrian, Ulrich H., Voisin, Mathieu-Benoit, Rot, Antal, Nourshargh, Sussan
Publicado 2018

Isoprenylcysteine Carboxylmethyltransferase-Based Therapy for Hutchinson–Gilford Progeria Syndrome

por Marcos-Ramiro, Beatriz, Gil-Ordóñez, Ana, Marín-Ramos, Nagore I., Ortega-Nogales, Francisco J., Balabasquer, Moisés, Gonzalo, Pilar, Khiar-Fernández, Nora, Rolas, Loïc, Barkaway, Anna, Nourshargh, Sussan, Andrés, Vicente, Martín-Fontecha, Mar, López-Rodríguez, María L., Ortega-Gutiérrez, Silvia
Publicado 2021

Cardiovascular Progerin Suppression and Lamin A Restoration Rescue Hutchinson-Gilford Progeria Syndrome

por Sánchez-López, Amanda, Espinós-Estévez, Carla, González-Gómez, Cristina, Gonzalo, Pilar, Andrés-Manzano, María J., Fanjul, Víctor, Riquelme-Borja, Raquel, Hamczyk, Magda R., Macías, Álvaro, del Campo, Lara, Camafeita, Emilio, Vázquez, Jesús, Barkaway, Anna, Rolas, Loïc, Nourshargh, Sussan, Dorado, Beatriz, Benedicto, Ignacio, Andrés, Vicente
Publicado 2021

Age-related changes in the local milieu of inflamed tissues cause aberrant neutrophil trafficking and subsequent remote organ damage

por Barkaway, Anna, Rolas, Loïc, Joulia, Régis, Bodkin, Jennifer, Lenn, Tchern, Owen-Woods, Charlotte, Reglero-Real, Natalia, Stein, Monja, Vázquez-Martínez, Laura, Girbl, Tamara, Poston, Robin N., Golding, Matthew, Saleeb, Rebecca S., Thiriot, Aude, von Andrian, Ulrich H., Duchene, Johan, Voisin, Mathieu-Benoit, Bishop, Cleo L., Voehringer, David, Roers, Axel, Rot, Antal, Lämmermann, Tim, Nourshargh, Sussan
Publicado 2021

Autophagy modulates endothelial junctions to restrain neutrophil diapedesis during inflammation

por Reglero-Real, Natalia, Pérez-Gutiérrez, Lorena, Yoshimura, Azumi, Rolas, Loïc, Garrido-Mesa, José, Barkaway, Anna, Pickworth, Catherine, Saleeb, Rebeca S., Gonzalez-Nuñez, Maria, Austin-Williams, Shani N., Cooper, Dianne, Vázquez-Martínez, Laura, Fu, Tao, De Rossi, Giulia, Golding, Matthew, Voisin, Mathieu-Benoit, Boulanger, Chantal M., Kubota, Yoshiaki, Muller, William A., Tooze, Sharon A., Nightingale, Thomas D., Collinson, Lucy, Perretti, Mauro, Aksoy, Ezra, Nourshargh, Sussan
Publicado 2021