The p80 homology region of TEP1 is sufficient for its association with the telomerase and vault RNAs, and the vault particle

por Poderycki, Michael J., Rome, Leonard H., Harrington, Lea, Kickhoefer, Valerie A.
Publicado 2005

Draft Crystal Structure of the Vault Shell at 9-Å Resolution

por Anderson, Daniel H, Kickhoefer, Valerie A, Sievers, Stuart A, Rome, Leonard H, Eisenberg, David
Publicado 2007

The 193-Kd Vault Protein, Vparp, Is a Novel Poly(Adp-Ribose) Polymerase

por Kickhoefer, Valerie A., Siva, Amara C., Kedersha, Nancy L., Inman, Elisabeth M., Ruland, Cristina, Streuli, Michel, Rome, Leonard H.
Publicado 1999

The Telomerase/Vault-Associated Protein Tep1 Is Required for Vault RNA Stability and Its Association with the Vault Particle

por Kickhoefer, Valerie A., Liu, Yie, Kong, Lawrence B., Snow, Bryan E., Stewart, Phoebe L., Harrington, Lea, Rome, Leonard H.
Publicado 2001

Polyribosomes Are Molecular 3D Nanoprinters That Orchestrate the Assembly of Vault Particles

por Mrazek, Jan, Toso, Daniel, Ryazantsev, Sergey, Zhang, Xing, Zhou, Z. Hong, Fernandez, Beatriz Campo, Kickhoefer, Valerie A., Rome, Leonard H.
Publicado 2014

A Protective Vaccine against Chlamydia Genital Infection Using Vault Nanoparticles without an Added Adjuvant

por Jiang, Janina, Liu, Guangchao, Kickhoefer, Valerie A., Rome, Leonard H., Li, Lin-Xi, McSorley, Stephen J., Kelly, Kathleen A.
Publicado 2017

Modulation of the Vault Protein-Protein Interaction for Tuning of Molecular Release

por Yu, Kang, Yau, Yin Hoe, Sinha, Ameya, Tan, Tabitha, Kickhoefer, Valerie A., Rome, Leonard H., Lee, Hwankyu, Shochat, Susana G., Lim, Sierin
Publicado 2017

Novel CCL21-Vault Nanocapsule Intratumoral Delivery Inhibits Lung Cancer Growth

por Kar, Upendra K., Srivastava, Minu K., Andersson, Åsa, Baratelli, Felicita, Huang, Min, Kickhoefer, Valerie A., Dubinett, Steven M., Rome, Leonard H., Sharma, Sherven
Publicado 2011

Vault Nanocapsules as Adjuvants Favor Cell-Mediated over Antibody-Mediated Immune Responses following Immunization of Mice

por Kar, Upendra K., Jiang, Janina, Champion, Cheryl I., Salehi, Sahar, Srivastava, Minu, Sharma, Sherven, Rabizadeh, Shahrooz, Niazi, Kayvan, Kickhoefer, Valerie, Rome, Leonard H., Kelly, Kathleen A.
Publicado 2012

A Vault Nanoparticle Vaccine Induces Protective Mucosal Immunity

por Champion, Cheryl I., Kickhoefer, Valerie A., Liu, Guangchao, Moniz, Raymond J., Freed, Amanda S., Bergmann, Liisa L., Vaccari, Dana, Raval-Fernandes, Sujna, Chan, Ann M., Rome, Leonard H., Kelly, Kathleen A.
Publicado 2009

Bioengineered Vaults: Self-Assembling Protein Shell–Lipophilic Core Nanoparticles for Drug Delivery

por Buehler, Daniel C., Marsden, Matthew D., Shen, Sean, Toso, Daniel B., Wu, Xiaomeng, Loo, Joseph A., Zhou, Z. Hong, Kickhoefer, Valerie A., Wender, Paul A., Zack, Jerome A., Rome, Leonard H.
Publicado 2014

Immunoediting role for major vault protein in apoptotic signaling induced by bacterial N-acyl homoserine lactones

por Rayo, Josep, Gregor, Rachel, Jacob, Nicholas T., Dandela, Rambabu, Dubinsky, Luba, Yashkin, Alex, Aranovich, Alexander, Thangaraj, Manikandan, Ernst, Orna, Barash, Eran, Malitsky, Sergey, Florea, Bogdan I., Krom, Bastiaan P., Wiemer, Erik A. C., Kickhoefer, Valerie A., Rome, Leonard H., Mathison, John C., Kaufmann, Gunnar F., Overkleeft, Herman S., Cravatt, Benjamin F., Zor, Tsaffrir, Janda, Kim D., Ulevitch, Richard J., Kravchenko, Vladimir V., Meijler, Michael M.
Publicado 2021

Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets

por Zhang, Qin, Jeppesen, Dennis K., Higginbotham, James N., Graves-Deal, Ramona, Trinh, Vincent Q., Ramirez, Marisol A., Sohn, Yoojin, Neininger, Abigail C., Taneja, Nilay, McKinley, Eliot T., Niitsu, Hiroaki, Cao, Zheng, Evans, Rachel, Glass, Sarah E., Ray, Kevin C., Fissell, William H., Hill, Salisha, Rose, Kristie Lindsey, Huh, Won Jae, Washington, Mary Kay, Ayers, Gregory Daniel, Burnette, Dylan T., Sharma, Shivani, Rome, Leonard H., Franklin, Jeffrey L., Lee, Youngmin A., Liu, Qi, Coffey, Robert J.
Publicado 2021