LRRK2-Related Parkinson’s Disease Due to Altered Endolysosomal Biology With Variable Lewy Body Pathology: A Hypothesis

por Rivero-Ríos, Pilar, Romo-Lozano, María, Fasiczka, Rachel, Naaldijk, Yahaira, Hilfiker, Sabine
Publicado 2020

Distinct Roles for RAB10 and RAB29 in Pathogenic LRRK2-Mediated Endolysosomal Trafficking Alterations

por Rivero-Ríos, Pilar, Romo-Lozano, Maria, Fernández, Belén, Fdez, Elena, Hilfiker, Sabine
Publicado 2020

The G2019S variant of leucine-rich repeat kinase 2 (LRRK2) alters endolysosomal trafficking by impairing the function of the GTPase RAB8A

por Rivero-Ríos, Pilar, Romo-Lozano, María, Madero-Pérez, Jesús, Thomas, Andrew P., Biosa, Alice, Greggio, Elisa, Hilfiker, Sabine
Publicado 2019

RAB8, RAB10 and RILPL1 contribute to both LRRK2 kinase–mediated centrosomal cohesion and ciliogenesis deficits

por Lara Ordónez, Antonio Jesús, Fernández, Belén, Fdez, Elena, Romo-Lozano, María, Madero-Pérez, Jesús, Lobbestael, Evy, Baekelandt, Veerle, Aiastui, Ana, López de Munaín, Adolfo, Melrose, Heather L, Civiero, Laura, Hilfiker, Sabine
Publicado 2019