CD5, an Undercover Regulator of TCR Signaling

por Voisinne, Guillaume, Gonzalez de Peredo, Anne, Roncagalli, Romain
Publicado 2018

EAT-2, a SAP-like adaptor, controls NK cell activation through phospholipase Cγ, Ca(++), and Erk, leading to granule polarization

por Pérez-Quintero, Luis-Alberto, Roncagalli, Romain, Guo, Huaijian, Latour, Sylvain, Davidson, Dominique, Veillette, André
Publicado 2014

Mapping the SLP76 interactome in T cells lacking each of the GRB2-family adaptors reveals molecular plasticity of the TCR signaling pathway

por Ruminski, Kilian, Celis-Gutierrez, Javier, Jarmuzynski, Nicolas, Maturin, Emilie, Audebert, Stephane, Malissen, Marie, Camoin, Luc, Voisinne, Guillaume, Malissen, Bernard, Roncagalli, Romain
Publicado 2023

Opposing regulatory functions of the TIM3 (HAVCR2) signalosome in primary effector T cells as revealed by quantitative interactomics

por Zhai, Yunhao, Celis-Gutierrez, Javier, Voisinne, Guillaume, Mori, Daiki, Girard, Laura, Burlet-Schiltz, Odile, de Peredo, Anne Gonzalez, Roncagalli, Romain, Malissen, Bernard
Publicado 2020

Quantitative Interactomics in Primary T Cells Provides a Rationale for Concomitant PD-1 and BTLA Coinhibitor Blockade in Cancer Immunotherapy

por Celis-Gutierrez, Javier, Blattmann, Peter, Zhai, Yunhao, Jarmuzynski, Nicolas, Ruminski, Kilian, Grégoire, Claude, Ounoughene, Youcef, Fiore, Frédéric, Aebersold, Ruedi, Roncagalli, Romain, Gstaiger, Matthias, Malissen, Bernard
Publicado 2019

Co‐recruitment analysis of the CBL and CBLB signalosomes in primary T cells identifies CD5 as a key regulator of TCR‐induced ubiquitylation

por Voisinne, Guillaume, García‐Blesa, Antonio, Chaoui, Karima, Fiore, Frédéric, Bergot, Elise, Girard, Laura, Malissen, Marie, Burlet‐Schiltz, Odile, Gonzalez de Peredo, Anne, Malissen, Bernard, Roncagalli, Romain
Publicado 2016

Kinetic proofreading through the multi-step activation of the ZAP70 kinase underlies early T cell ligand discrimination

por Voisinne, Guillaume, Locard-Paulet, Marie, Froment, Carine, Maturin, Emilie, Menoita, Marisa Goncalves, Girard, Laura, Mellado, Valentin, Burlet-Schiltz, Odile, Malissen, Bernard, Gonzalez de Peredo, Anne, Roncagalli, Romain
Publicado 2022

Fit αβ T-cell receptor suppresses leukemogenesis of Pten-deficient thymocytes

por Gon, Stéphanie, Loosveld, Marie, Crouzet, Thomas, Potier, Delphine, Bonnet, Mélanie, Morin, Stéphanie O., Michel, Gérard, Vey, Norbert, Nunès, Jacques A., Malissen, Bernard, Roncagalli, Romain, Nadel, Bertrand, Payet-Bornet, Dominique
Publicado 2018

The T cell CD6 receptor operates a multitask signalosome with opposite functions in T cell activation

por Mori, Daiki, Grégoire, Claude, Voisinne, Guillaume, Celis-Gutierrez, Javier, Aussel, Rudy, Girard, Laura, Camus, Mylène, Marcellin, Marlène, Argenty, Jérémy, Burlet-Schiltz, Odile, Fiore, Frédéric, Gonzalez de Peredo, Anne, Malissen, Marie, Roncagalli, Romain, Malissen, Bernard
Publicado 2020

Systems-level conservation of the proximal TCR signaling network of mice and humans

por Nicolas, Philippe, Ollier, Jocelyn, Mori, Daiki, Voisinne, Guillaume, Celis-Gutierrez, Javier, Gregoire, Claude, Perroteau, Jeanne, Vivien, Régine, Camus, Mylène, Burlet-Schiltz, Odile, Gonzalez de Peredo, Anne, Clémenceau, Béatrice, Roncagalli, Romain, Vié, Henri, Malissen, Bernard
Publicado 2022

The scaffolding function of the RLTPR protein explains its essential role for CD28 co-stimulation in mouse and human T cells

por Roncagalli, Romain, Cucchetti, Margot, Jarmuzynski, Nicolas, Grégoire, Claude, Bergot, Elise, Audebert, Stéphane, Baudelet, Emilie, Menoita, Marisa Goncalves, Joachim, Anais, Durand, Stéphane, Suchanek, Miloslav, Fiore, Frédéric, Zhang, Lichen, Liang, Yinming, Camoin, Luc, Malissen, Marie, Malissen, Bernard
Publicado 2016

ARHGAP45 controls naïve T‐ and B‐cell entry into lymph nodes and T‐cell progenitor thymus seeding

por He, Le, Valignat, Marie‐Pierre, Zhang, Lichen, Gelard, Lena, Zhang, Fanghui, Le Guen, Valentin, Audebert, Stéphane, Camoin, Luc, Fossum, Even, Bogen, Bjarne, Wang, Hui, Henri, Sandrine, Roncagalli, Romain, Theodoly, Olivier, Liang, Yinming, Malissen, Marie, Malissen, Bernard
Publicado 2021

LymphoAtlas: a dynamic and integrated phosphoproteomic resource of TCR signaling in primary T cells reveals ITSN2 as a regulator of effector functions

por Locard‐Paulet, Marie, Voisinne, Guillaume, Froment, Carine, Goncalves Menoita, Marisa, Ounoughene, Youcef, Girard, Laura, Gregoire, Claude, Mori, Daiki, Martinez, Manuel, Luche, Hervé, Garin, Jerôme, Malissen, Marie, Burlet‐Schiltz, Odile, Malissen, Bernard, Gonzalez de Peredo, Anne, Roncagalli, Romain
Publicado 2020

A THEMIS:SHP1 complex promotes T-cell survival

por Paster, Wolfgang, Bruger, Annika M, Katsch, Kristin, Grégoire, Claude, Roncagalli, Romain, Fu, Guo, Gascoigne, Nicholas RJ, Nika, Konstantina, Cohnen, Andre, Feller, Stephan M, Simister, Philip C, Molder, Kelly C, Cordoba, Shaun-Paul, Dushek, Omer, Malissen, Bernard, Acuto, Oreste
Publicado 2015

CD6 modulates thymocyte selection and peripheral T cell homeostasis

por Orta-Mascaró, Marc, Consuegra-Fernández, Marta, Carreras, Esther, Roncagalli, Romain, Carreras-Sureda, Amado, Alvarez, Pilar, Girard, Laura, Simões, Inês, Martínez-Florensa, Mario, Aranda, Fernando, Merino, Ramón, Martínez, Vanesa-Gabriela, Vicente, Rubén, Merino, Jesús, Sarukhan, Adelaida, Malissen, Marie, Malissen, Bernard, Lozano, Francisco
Publicado 2016

Quantitative interactomics in primary T cells unveils TCR signal diversification extent and dynamics

por Voisinne, Guillaume, Kersse, Kristof, Chaoui, Karima, Lu, Liaoxun, Chaix, Julie, Zhang, Lichen, Menoita, Marisa Goncalves, Girard, Laura, Ounoughene, Youcef, Wang, Hui, Burlet-Schiltz, Odile, Luche, Hervé, Fiore, Frédéric, Malissen, Marie, de Peredo, Anne Gonzalez, Liang, Yinming, Roncagalli, Romain, Malissen, Bernard
Publicado 2019

Precise Temporal Profiling of Signaling Complexes in Primary Cells Using SWATH Mass Spectrometry

por Caron, Etienne, Roncagalli, Romain, Hase, Takeshi, Wolski, Witold E., Choi, Meena, Menoita, Marisa G., Durand, Stephane, García-Blesa, Antonio, Fierro-Monti, Ivo, Sajic, Tatjana, Heusel, Moritz, Weiss, Tobias, Malissen, Marie, Schlapbach, Ralph, Collins, Ben C., Ghosh, Samik, Kitano, Hiroaki, Aebersold, Ruedi, Malissen, Bernard, Gstaiger, Matthias
Publicado 2017

Dual T cell– and B cell–intrinsic deficiency in humans with biallelic RLTPR mutations

por Wang, Yi, Ma, Cindy S., Ling, Yun, Bousfiha, Aziz, Camcioglu, Yildiz, Jacquot, Serge, Payne, Kathryn, Crestani, Elena, Roncagalli, Romain, Belkadi, Aziz, Kerner, Gaspard, Lorenzo, Lazaro, Deswarte, Caroline, Chrabieh, Maya, Patin, Etienne, Vincent, Quentin B., Müller-Fleckenstein, Ingrid, Fleckenstein, Bernhard, Ailal, Fatima, Quintana-Murci, Lluis, Fraitag, Sylvie, Alyanakian, Marie-Alexandra, Leruez-Ville, Marianne, Picard, Capucine, Puel, Anne, Bustamante, Jacinta, Boisson-Dupuis, Stéphanie, Malissen, Marie, Malissen, Bernard, Abel, Laurent, Hovnanian, Alain, Notarangelo, Luigi D., Jouanguy, Emmanuelle, Tangye, Stuart G., Béziat, Vivien, Casanova, Jean-Laurent
Publicado 2016