Engineered T Regulatory Type 1 Cells for Clinical Application

por Gregori, Silvia, Roncarolo, Maria Grazia
Publicado 2018

Graft Engineering and Adoptive Immunotherapy: New Approaches to Promote Immune Tolerance After Hematopoietic Stem Cell Transplantation

por Bertaina, Alice, Roncarolo, Maria Grazia
Publicado 2019

Granulocyte-colony stimulating factor drives the in vitro differentiation of human dendritic cells that induce anergy in naïve T cells

por Rossetti, Maura, Gregori, Silvia, Roncarolo, Maria Grazia
Publicado 2010

The Cellular and Molecular Mechanisms of Immuno-Suppression by Human Type 1 Regulatory T Cells

por Gregori, Silvia, Goudy, Kevin S., Roncarolo, Maria Grazia
Publicado 2012

Clinical Outlook for Type-1 and FOXP3(+) T Regulatory Cell-Based Therapy

por Gregori, Silvia, Passerini, Laura, Roncarolo, Maria-Grazia
Publicado 2015

Gene therapy for ADA‐SCID, the first marketing approval of an ex vivo gene therapy in Europe: paving the road for the next generation of advanced therapy medicinal products

por Aiuti, Alessandro, Roncarolo, Maria Grazia, Naldini, Luigi
Publicado 2017

Differentiation of T Regulatory Cells by Immature Dendritic Cells

por Roncarolo, Maria-Grazia, Levings, Megan K., Traversari, Catia
Publicado 2001

Human Cd25(+)Cd4(+) T Regulatory Cells Suppress Naive and Memory T Cell Proliferation and Can Be Expanded in Vitro without Loss of Function

por Levings, Megan K., Sangregorio, Romina, Roncarolo, Maria-Grazia
Publicado 2001

Type 1 regulatory T cell-mediated tolerance in health and disease

por Freeborn, Robert A., Strubbe, Steven, Roncarolo, Maria Grazia
Publicado 2022

Type 1 regulatory T (Tr1) cells: from the bench to the bedside

por Gregori, Silvia, Bacchetta, Rosa, Battaglia, Manuela, Roncarolo, Maria Grazia
Publicado 2012

The Yin and Yang of Type 1 Regulatory T Cells: From Discovery to Clinical Application

por Sayitoglu, Ece Canan, Freeborn, Robert Arthur, Roncarolo, Maria Grazia
Publicado 2021

Manipulating Immune Tolerance with Micro-RNA Regulated Gene Therapy

por Goudy, Kevin Scott, Annoni, Andrea, Naldini, Luigi, Roncarolo, Maria-Grazia
Publicado 2011

Concise Review: Cell‐Based Therapies and Other Non‐Traditional Approaches for Type 1 Diabetes

por Creusot, Remi J., Battaglia, Manuela, Roncarolo, Maria‐Grazia, Fathman, C. Garrison
Publicado 2016

Rapamycin Prevents and Breaks the Anti-CD3–Induced Tolerance in NOD Mice

por Valle, Andrea, Jofra, Tatiana, Stabilini, Angela, Atkinson, Mark, Roncarolo, Maria-Grazia, Battaglia, Manuela
Publicado 2009

Co-Expression of FOXP3FL and FOXP3Δ2 Isoforms Is Required for Optimal Treg-Like Cell Phenotypes and Suppressive Function

por Sato, Yohei, Liu, Jessica, Lee, Esmond, Perriman, Rhonda, Roncarolo, Maria Grazia, Bacchetta, Rosa
Publicado 2021

APVO210: A Bispecific Anti-CD86-IL-10 Fusion Protein (ADAPTIR™) to Induce Antigen-Specific T Regulatory Type 1 Cells

por Pellerin, Laurence, Chen, Ping, Gregori, Silvia, Hernandez-Hoyos, Gabriela, Bacchetta, Rosa, Roncarolo, Maria Grazia
Publicado 2018

Antigen-Specific Dependence of Tr1-Cell Therapy in Preclinical Models of Islet Transplant

por Gagliani, Nicola, Jofra, Tatiana, Stabilini, Angela, Valle, Andrea, Atkinson, Mark, Roncarolo, Maria-Grazia, Battaglia, Manuela
Publicado 2010

Killing of myeloid APCs via HLA class I, CD2 and CD226 defines a novel mechanism of suppression by human Tr1 cells

por Magnani, Chiara F, Alberigo, Giada, Bacchetta, Rosa, Serafini, Giorgia, Andreani, Marco, Roncarolo, Maria Grazia, Gregori, Silvia
Publicado 2011

Rapamycin Monotherapy in Patients With Type 1 Diabetes Modifies CD4(+)CD25(+)FOXP3(+) Regulatory T-Cells

por Monti, Paolo, Scirpoli, Miriam, Maffi, Paola, Piemonti, Lorenzo, Secchi, Antonio, Bonifacio, Ezio, Roncarolo, Maria-Grazia, Battaglia, Manuela
Publicado 2008

Human CD25(+)CD4(+) T Suppressor Cell Clones Produce Transforming Growth Factor β, but not Interleukin 10, and Are Distinct from Type 1 T Regulatory Cells

por Levings, Megan K., Sangregorio, Romina, Sartirana, Claudia, Moschin, Anna Lisa, Battaglia, Manuela, Orban, Paul C., Roncarolo, Maria-Grazia
Publicado 2002