In vivo siRNA delivery of Keap1 modulates death and survival signaling pathways and attenuates concanavalin-A-induced acute liver injury in mice

por González-Rodríguez, Águeda, Reibert, Bjorn, Amann, Thomas, Constien, Rainier, Rondinone, Cristina M., Valverde, Ángela M.
Publicado 2014

Differential Effects of a Glucagon-Like Peptide 1 Receptor Agonist in Non-Alcoholic Fatty Liver Disease and in Response to Hepatectomy

por Valdecantos, M. Pilar, Ruiz, Laura, Pardo, Virginia, Castro-Sanchez, Luis, García-Monzón, Carmelo, Lanzón, Borja, Rupérez, Javier, Barbas, Coral, Naylor, Jaqueline, Trevaskis, James L., Grimsby, Joseph, Rondinone, Cristina M., Valverde, Ángela M.
Publicado 2018

Delivery of RNAi reagents in murine models of obesity and diabetes

por Wilcox, Denise M, Yang, Ruojing, Morgan, Sherry J, Nguyen, Phong T, Voorbach, Martin J, Jung, Paul M, Haasch, Deanna L, Lin, Emily, Bush, Eugene N, Opgenorth, Terry J, Jacobson, Peer B, Collins, Christine A, Rondinone, Cristina M, Surowy, Terry, Landschulz, Katherine T
Publicado 2006

Resolution of NASH and hepatic fibrosis by the GLP-1R/GcgR dual-agonist Cotadutide via modulating mitochondrial function and lipogenesis.

por Boland, Michelle L., Laker, Rhianna C., Mather, Karly, Nawrocki, Arkadiusz, Oldham, Stephanie, Boland, Brandon B., Lewis, Hilary, Conway, James, Naylor, Jacqueline, Guionaud, Silvia, Feigh, Michael, Veidal, Sanne S., Lantier, Louise, McGuinness, Owen P., Grimsby, Joseph, Rondinone, Cristina M., Jermutus, Lutz, Larsen, Martin R., Trevaskis, James L., Rhodes, Christopher J.
Publicado 2020

High-throughput mediation analysis of human proteome and metabolome identifies mediators of post-bariatric surgical diabetes control

por Dreyfuss, Jonathan M., Yuchi, Yixing, Dong, Xuehong, Efthymiou, Vissarion, Pan, Hui, Simonson, Donald C., Vernon, Ashley, Halperin, Florencia, Aryal, Pratik, Konkar, Anish, Sebastian, Yinong, Higgs, Brandon W., Grimsby, Joseph, Rondinone, Cristina M., Kasif, Simon, Kahn, Barbara B., Foster, Kathleen, Seeley, Randy, Goldfine, Allison, Djordjilović, Vera, Patti, Mary Elizabeth
Publicado 2021

Engineering of a GLP-1 analogue peptide/anti-PCSK9 antibody fusion for type 2 diabetes treatment

por Chodorge, Matthieu, Celeste, Anthony J., Grimsby, Joseph, Konkar, Anish, Davidsson, Pia, Fairman, David, Jenkinson, Lesley, Naylor, Jacqueline, White, Nicholas, Seaman, Jonathan C., Dickson, Karen, Kemp, Benjamin, Spooner, Jennifer, Rossy, Emmanuel, Hornigold, David C., Trevaskis, James L., Bond, Nicholas J., London, Timothy B., Buchanan, Andrew, Vaughan, Tristan, Rondinone, Cristina M., Osbourn, Jane K.
Publicado 2018