Role of transcription-regulating kinase CDK8 in colon cancer metastasis

por Liang, Jiaxin, Chen, Mengqian, Broude, Eugenia V., Roninson, Igor B.
Publicado 2019

Graphene-incorporated hyaluronic acid-based hydrogel as a controlled Senexin A delivery system

por Maturavongsadit, Panita, Wu, Weiwei, Fan, Jingyu, Roninson, Igor B., Cui, Taixing, Wang, Qian
Publicado 2022

Characterizing CDK8/19 Inhibitors through a NFκB-Dependent Cell-Based Assay

por Li, Jing, Ji, Hao, Porter, Donald C., Broude, Eugenia V., Roninson, Igor B., Chen, Mengqian
Publicado 2019

Systemic Toxicity Reported for CDK8/19 Inhibitors CCT251921 and MSC2530818 Is Not Due to Target Inhibition

por Chen, Mengqian, Li, Jing, Liang, Jiaxin, Thompson, Zanshé S., Kathrein, Katie, Broude, Eugenia V., Roninson, Igor B.
Publicado 2019

Identifying Cancers Impacted by CDK8/19

por Roninson, Igor B., Győrffy, Balázs, Mack, Zachary T., Shtil, Alexander A., Shtutman, Michael S., Chen, Mengqian, Broude, Eugenia V.
Publicado 2019

A structural interpretation of the effect of GC-content on efficiency of RNA interference

por Chan, Chi Yu, Carmack, C Steven, Long, Dang D, Maliyekkel, Anil, Shao, Yu, Roninson, Igor B, Ding, Ye
Publicado 2009

Identification of single nucleotide polymorphisms in the p21 (CDKN1A) gene and correlations with longevity in the Italian population

por Gravina, Silvia, Lescai, Francesco, Hurteau, Gregory, Brock, Graham J., Saramaki, Anna, Salvioli, Stefano, Franceschi, Claudio, Roninson, Igor B.
Publicado 2009

Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1

por Alam, Amer, Küng, Raphael, Kowal, Julia, McLeod, Robert A., Tremp, Nina, Broude, Eugenia V., Roninson, Igor B., Stahlberg, Henning, Locher, Kaspar P.
Publicado 2018

Clinical Correlations of Polycomb Repressive Complex 2 in Different Tumor Types

por Erokhin, Maksim, Chetverina, Olga, Győrffy, Balázs, Tatarskiy, Victor V., Mogila, Vladic, Shtil, Alexander A., Roninson, Igor B., Moreaux, Jerome, Georgiev, Pavel, Cavalli, Giacomo, Chetverina, Darya
Publicado 2021

The Inhibition of CDK8/19 Mediator Kinases Prevents the Development of Resistance to EGFR-Targeting Drugs

por Sharko, Amanda C., Lim, Chang-Uk, McDermott, Martina S. J., Hennes, Chuck, Philavong, Kingsavanh P., Aiken, Tiffanie, Tatarskiy, Victor V., Roninson, Igor B., Broude, Eugenia V.
Publicado 2021

Identification of novel genes that regulate androgen receptor signaling and growth of androgen-deprived prostate cancer cells

por Levina, Elina, Ji, Hao, Chen, Mengqiang, Baig, Mirza, Oliver, David, Ohouo, Patrice, Lim, Chang-uk, Schools, Garry, Carmack, Steven, Ding, Ye, Broude, Eugenia V., Roninson, Igor B., Buttyan, Ralph, Shtutman, Michael
Publicado 2015

Inhibition of CDK8 mediator kinase suppresses estrogen dependent transcription and the growth of estrogen receptor positive breast cancer

por McDermott, Martina S.J., Chumanevich, Alexander A., Lim, Chang-uk, Liang, Jiaxin, Chen, Mengqian, Altilia, Serena, Oliver, David, Rae, James M., Shtutman, Michael, Kiaris, Hippokratis, Győrffy, Balázs, Roninson, Igor B., Broude, Eugenia V.
Publicado 2017

Inhibition of Cyclin-Dependent Kinases 8/19 Restricts Bacterial and Virus-Induced Inflammatory Responses in Monocytes

por Kokinos, Elena K., Tsymbal, Sergey A., Galochkina, Anastasia V., Bezlepkina, Svetlana A., Nikolaeva, Julia V., Vershinina, Sofia O., Shtro, Anna A., Tatarskiy, Victor V., Shtil, Alexander A., Broude, Eugenia V., Roninson, Igor B., Dukhinova, Marina
Publicado 2023

Inhibition of CDK8/19 Mediator kinase potentiates HER2-targeting drugs and bypasses resistance to these agents in vitro and in vivo

por Ding, Xiaokai, Sharko, Amanda C., McDermott, Martina S. J., Schools, Gary P., Chumanevich, Alexander, Ji, Hao, Li, Jing, Zhang, Li, Mack, Zachary T., Sikirzhytski, Vitali, Shtutman, Michael, Ivers, Laura, O’Donovan, Norma, Crown, John, Győrffy, Balázs, Chen, Mengqian, Roninson, Igor B., Broude, Eugenia V.
Publicado 2022

CDK8 and CDK19: positive regulators of signal-induced transcription and negative regulators of Mediator complex proteins

por Chen, Mengqian, Li, Jing, Zhang, Li, Wang, Lili, Cheng, Chen, Ji, Hao, Altilia, Serena, Ding, Xiaokai, Cai, Guoshuai, Altomare, Diego, Shtutman, Michael, Byrum, Stephanie D, Mackintosh, Samuel G, Feoktistov, Alexey, Soshnikova, Nataliya, Mogila, Vladislav A, Tatarskiy, Victor, Erokhin, Maksim, Chetverina, Darya, Prawira, Angga, Ni, Yi, Urban, Stephan, McInnes, Campbell, Broude, Eugenia V, Roninson, Igor B
Publicado 2023