Patient-derived organoids as a predictive biomarker for treatment response in cancer patients

por Wensink, G. Emerens, Elias, Sjoerd G., Mullenders, Jasper, Koopman, Miriam, Boj, Sylvia F., Kranenburg, Onno W., Roodhart, Jeanine M. L.
Publicado 2021

Mismatch Repair Status in Patient-Derived Colorectal Cancer Organoids Does Not Affect Intrinsic Tumor Cell Sensitivity to Systemic Therapy

por Küçükköse, Emre, Wensink, G. Emerens, Roelse, Celine M., van Schelven, Susanne J., Raats, Daniëlle A. E., Boj, Sylvia F., Koopman, Miriam, Laoukili, Jamila, Roodhart, Jeanine M. L., Kranenburg, Onno
Publicado 2021

The Prospective Dutch Colorectal Cancer (PLCRC) cohort: real-world data facilitating research and clinical care

por Derksen, Jeroen W. G., Vink, Geraldine R., Elferink, Marloes A. G., Roodhart, Jeanine M. L., Verkooijen, Helena M., van Grevenstein, Wilhelmina M. U., Siersema, Peter D., May, Anne M., Koopman, Miriam
Publicado 2021

External Validation of the Colon Life Nomogram for Predicting 12-Week Mortality in Dutch Metastatic Colorectal Cancer Patients Treated with Trifluridine/Tipiracil in Daily Practice

por Hamers, Patricia A. H., Wensink, G. Emerens, van Smeden, Maarten, Vink, Geraldine R., Smabers, Lidwien P., Lunenberg, Renee A., Laclé, Miangela M., Koopman, Miriam, May, Anne M., Roodhart, Jeanine M. L.
Publicado 2022

Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice

por Küçükköse, Emre, Heesters, Balthasar A, Villaudy, Julien, Verheem, André, Cercel, Madalina, van Hal, Susan, Boj, Sylvia F, Borel Rinkes, Inne H M, Punt, Cornelis J A, Roodhart, Jeanine M L, Laoukili, Jamila, Koopman, Miriam, Spits, Hergen, Kranenburg, Onno
Publicado 2022

Predicting early extrahepatic recurrence after local treatment of colorectal liver metastases

por Wensink, G E, Bolhuis, Karen, Elferink, Marloes A G, Fijneman, Remond J A, Kranenburg, Onno, Borel Rinkes, Inne H M, Koopman, Miriam, Swijnenburg, Rutger-Jan, Vink, Geraldine R, Hagendoorn, Jeroen, Punt, Cornelis J A, Roodhart, Jeanine M L, Elias, Sjoerd G
Publicado 2023

Correlation of Immunological and Histopathological Features with Gene Expression-Based Classifiers in Colon Cancer Patients

por van de Weerd, Simone, Smit, Marloes A., Roelands, Jessica, Mesker, Wilma E., Bedognetti, Davide, Kuppen, Peter J. K., Putter, Hein, Tollenaar, Rob A. E. M., Roodhart, Jeanine M. L., Hendrickx, Wouter, Medema, Jan Paul, van Krieken, J. Han J. M.
Publicado 2022

Prognostic value of Lynch syndrome, BRAF(V600E) , and RAS mutational status in dMMR/MSI‐H metastatic colorectal cancer in a pooled analysis of Dutch and French cohorts

por Zwart, Koen, van der Baan, Frederieke H., Cohen, Romain, Aparicio, Thomas, de la Fouchardiére, Christelle, Lecomte, Thierry, Punt, Cornelis J. A., Sefrioui, David, Verheijden, Rik J., Vink, Geraldine R., Wensink, G. Emerens, Zaanan, Aziz, Koopman, Miriam, Tougeron, David, Roodhart, Jeanine M. L.
Publicado 2023

Fatty acid 16:4(n-3) stimulates a GPR120-induced signaling cascade in splenic macrophages to promote chemotherapy resistance

por Houthuijzen, Julia M., Oosterom, Ilse, Hudson, Brian D., Hirasawa, Akira, Daenen, Laura G. M., McLean, Chelsea M., Hansen, Steffen V. F., van Jaarsveld, Marijn T. M., Peeper, Daniel S., Jafari Sadatmand, Sahar, Roodhart, Jeanine M. L., van de Lest, Chris H. A., Ulven, Trond, Ishihara, Kenji, Milligan, Graeme, Voest, Emile E.
Publicado 2017

External Validation of Two Established Clinical Risk Scores Predicting Outcome after Local Treatment of Colorectal Liver Metastases in a Nationwide Cohort

por Bolhuis, Karen, Wensink, G. Emerens, Elferink, Marloes A. G., Bond, Marinde J. G., Dijksterhuis, Willemieke P. M., Fijneman, Remond J. A., Kranenburg, Onno W., Rinkes, Inne H. M. Borel, Koopman, Miriam, Swijnenburg, Rutger-Jan, Vink, Geraldine R., Hagendoorn, Jeroen, Punt, Cornelis J. A., Elias, Sjoerd G., Roodhart, Jeanine M. L.
Publicado 2022

Consensus molecular subtype 4 (CMS4)-targeted therapy in primary colon cancer: A proof-of-concept study

por Peters, Niek A., Constantinides, Alexander, Ubink, Inge, van Kuik, Joyce, Bloemendal, Haiko J., van Dodewaard, Joyce M., Brink, Menno A., Schwartz, Thijs P., Lolkema, Martijn P.J.K., Lacle, Miangela M., Moons, Leon M., Geesing, Joost, van Grevenstein, Wilhelmina M.U., Roodhart, Jeanine M. L., Koopman, Miriam, Elias, Sjoerd G., Borel Rinkes, Inne H.M., Kranenburg, Onno
Publicado 2022

Survival of patients with deficient mismatch repair metastatic colorectal cancer in the pre-immunotherapy era

por Wensink, G. Emerens, Elferink, Marloes A. G., May, Anne M., Mol, Linda, Hamers, Patricia A. H., Bakker, Sandra D., Creemers, Geert-Jan, de Groot, Jan Willem B., de Klerk, Gerty J., Haberkorn, Brigitte C. M., Haringhuizen, Annebeth W., Hoekstra, Ronald, Hunting, J. Cornelis B., Kerver, Emile D., Mathijssen-van Stein, Danielle, Polée, Marco B., Pruijt, Johannes F. M., Quarles van Ufford-Mannesse, Patricia, Radema, Sandra, Rietbroek, Ronald C., Simkens, Lieke H. J., Tanis, Bea C., ten Bokkel Huinink, Daan, Tjin-A-Ton, Manuel L. R., Tromp-van Driel, Cathrien S., Troost, Monique M., van de Wouw, Agnes J., van den Berkmortel, Franchette W. P. J., van der Pas, Anke J. M., van der Velden, Ankie M. T., van Dijk, Marjan A., van Dodewaard-de Jong, Joyce M., van Druten, Edith B., van Voorthuizen, Theo, Jan Veldhuis, Gerrit, Verheul, Henk M. W., Vestjens, Hanneke J. H. M. J., Vincent, Jeroen, Kranenburg, Onno W., Punt, Cornelis J. A., Vink, Geraldine R., Roodhart, Jeanine M. L., Koopman, Miriam
Publicado 2020