Complement inhibition by gram-positive pathogens: molecular mechanisms and therapeutic implications

por Laarman, Alexander, Milder, Fin, van Strijp, Jos, Rooijakkers, Suzan
Publicado 2010

Let’s Tie the Knot: Marriage of Complement and Adaptive Immunity in Pathogen Evasion, for Better or Worse

por Bennett, Kaila M., Rooijakkers, Suzan H. M., Gorham, Ronald D.
Publicado 2017

New Insights into the Complement Receptor of the Ig Superfamily Obtained from Structural and Functional Studies on Two Mutants

por Duan, Huiquan, Abram, Troy G., Cruz, Ana Rita, Rooijakkers, Suzan H. M., Geisbrecht, Brian V.
Publicado 2023

Acquisition of C1 inhibitor by Bordetella pertussis virulence associated gene 8 results in C2 and C4 consumption away from the bacterial surface

por Hovingh, Elise S., van den Broek, Bryan, Kuipers, Betsy, Pinelli, Elena, Rooijakkers, Suzan H. M., Jongerius, Ilse
Publicado 2017

Neonatal sepsis and transient immunodeficiency: Potential for novel immunoglobulin therapies?

por Beudeker, Coco R., Vijlbrief, Daniel C., van Montfrans, Joris M., Rooijakkers, Suzan H.M., van der Flier, Michiel
Publicado 2022

Staphylococcal protein Ecb impairs complement receptor-1 mediated recognition of opsonized bacteria

por Amdahl, Hanne, Haapasalo, Karita, Tan, Lydia, Meri, Taru, Kuusela, Pentti I., van Strijp, Jos A., Rooijakkers, Suzan, Jokiranta, T. Sakari
Publicado 2017

Staphylococcus aureus Depends on Eap Proteins for Preventing Degradation of Its Phenol-Soluble Modulin Toxins by Neutrophil Serine Proteases

por Kretschmer, Dorothee, Breitmeyer, Ricarda, Gekeler, Cordula, Lebtig, Marco, Schlatterer, Katja, Nega, Mulugeta, Stahl, Mark, Stapels, Daphne, Rooijakkers, Suzan, Peschel, Andreas
Publicado 2021

Human Complement Inhibits Myophages against Pseudomonas aeruginosa

por Egido, Julia E., Dekker, Simon O., Toner-Bartelds, Catherine, Lood, Cédric, Rooijakkers, Suzan H. M., Bardoel, Bart W., Haas, Pieter-Jan
Publicado 2023

Staphylococcal complement evasion by various convertase-blocking molecules

por Jongerius, Ilse, Köhl, Jörg, Pandey, Manoj K., Ruyken, Maartje, van Kessel, Kok P.M., van Strijp, Jos A.G., Rooijakkers, Suzan H.M.
Publicado 2007

M1T1 group A streptococcal pili promote epithelial colonization but diminish systemic virulence through neutrophil extracellular entrapment

por Crotty Alexander, Laura E., Maisey, Heather C., Timmer, Anjuli M., Rooijakkers, Suzan H. M., Gallo, Richard L., von Köckritz-Blickwede, Maren, Nizet, Victor
Publicado 2009

Bacterial killing by complement requires direct anchoring of membrane attack complex precursor C5b-7

por Doorduijn, Dennis J., Bardoel, Bart W., Heesterbeek, Dani A. C., Ruyken, Maartje, Benn, Georgina, Parsons, Edward S., Hoogenboom, Bart W., Rooijakkers, Suzan H. M.
Publicado 2020

Use of Flow Cytometry to Evaluate Phagocytosis of Staphylococcus aureus by Human Neutrophils

por Boero, Elena, Brinkman, Iris, Juliet, Thessely, van Yperen, Eline, van Strijp, Jos A. G., Rooijakkers, Suzan H. M., van Kessel, Kok P. M.
Publicado 2021

Soluble MAC is primarily released from MAC-resistant bacteria that potently convert complement component C5

por Doorduijn, Dennis J, Lukassen, Marie V, van 't Wout, Marije FL, Franc, Vojtech, Ruyken, Maartje, Bardoel, Bart W, Heck, Albert JR, Rooijakkers, Suzan HM
Publicado 2022

Monitoring phage-induced lysis of gram-negatives in real time using a fluorescent DNA dye

por Egido, Julia E., Toner-Bartelds, Catherine, Costa, Ana Rita, Brouns, Stan J. J., Rooijakkers, Suzan H. M., Bardoel, Bart W., Haas, Pieter-Jan
Publicado 2023

Characterization of rapid neutrophil extracellular trap formation and its cooperation with phagocytosis in human neutrophils

por Saffarzadeh, Mona, Cabrera-Fuentes, Hector A., Veit, Florian, Jiang, Dongsheng, Scharffetter-Kochanek, Karin, Gille, Christian Gille, Rooijakkers, Suzan H. M., Hartl, Dominik, Preissner, Klaus T.
Publicado 2014

Molecular insights into the surface-specific arrangement of complement C5 convertase enzymes

por Berends, Evelien T. M., Gorham, Ronald D., Ruyken, Maartje, Soppe, Jasper A., Orhan, Hatice, Aerts, Piet C., de Haas, Carla J. C., Gros, Piet, Rooijakkers, Suzan H. M.
Publicado 2015

Functional Characterization of Alternative and Classical Pathway C3/C5 Convertase Activity and Inhibition Using Purified Models

por Zwarthoff, Seline A., Berends, Evelien T. M., Mol, Sanne, Ruyken, Maartje, Aerts, Piet C., Józsi, Mihály, de Haas, Carla J. C., Rooijakkers, Suzan H. M., Gorham, Ronald D.
Publicado 2018

Outer membrane permeabilization by the membrane attack complex sensitizes Gram-negative bacteria to antimicrobial proteins in serum and phagocytes

por Heesterbeek, Dani A. C., Muts, Remy M., van Hensbergen, Vincent P., de Saint Aulaire, Pieter, Wennekes, Tom, Bardoel, Bart W., van Sorge, Nina M., Rooijakkers, Suzan H. M.
Publicado 2021

Polymerization of C9 enhances bacterial cell envelope damage and killing by membrane attack complex pores

por Doorduijn, Dennis J., Heesterbeek, Dani A. C., Ruyken, Maartje, de Haas, Carla J. C., Stapels, Daphne A. C., Aerts, Piet C., Rooijakkers, Suzan H. M., Bardoel, Bart W.
Publicado 2021

Correction: Polymerization of C9 enhances bacterial cell envelope damage and killing by membrane attack complex pores

por Doorduijn, Dennis J., Heesterbeek, Dani A. C., Ruyken, Maartje, de Haas, Carla J. C., Stapels, Daphne A. C., Aerts, Piet C., Rooijakkers, Suzan H. M., Bardoel, Bart W.
Publicado 2022