Sirtainties in pancreatic cancer?

por Rooman, Ilse
Publicado 2014

Exploring new uses for existing drugs: innovative mechanisms to fund independent clinical research

por Verbaanderd, Ciska, Rooman, Ilse, Huys, Isabelle
Publicado 2021

Adult human pancreatic acinar cells dedifferentiate into an embryonic progenitor-like state in 3D suspension culture

por Baldan, Jonathan, Houbracken, Isabelle, Rooman, Ilse, Bouwens, Luc
Publicado 2019

On-Label or Off-Label? Overcoming Regulatory and Financial Barriers to Bring Repurposed Medicines to Cancer Patients

por Verbaanderd, Ciska, Rooman, Ilse, Meheus, Lydie, Huys, Isabelle
Publicado 2020

Heterotopia of salivary gland tissue in the pancreas

por Martens, Sandrina, Coolens, Katarina, Olsen, Catharina, Lefesvre, Pierre, Rooman, Ilse
Publicado 2023

Repurposing Drugs in Oncology (ReDO)—Propranolol as an anti-cancer agent

por Pantziarka, Pan, Bouche, Gauthier, Sukhatme, Vidula, Meheus, Lydie, Rooman, Ilse, Sukhatme, Vikas P
Publicado 2016

Nicotinamide combined with gemcitabine is an immunomodulatory therapy that restrains pancreatic cancer in mice

por Selvanesan, Benson Chellakkan, Meena, Kiran, Beck, Amanda, Meheus, Lydie, Lara, Olaya, Rooman, Ilse, Gravekamp, Claudia
Publicado 2020

On the Origin of Pancreatic Cancer: Molecular Tumor Subtypes in Perspective of Exocrine Cell Plasticity

por Backx, Elyne, Coolens, Katarina, Van den Bossche, Jan-Lars, Houbracken, Isabelle, Espinet, Elisa, Rooman, Ilse
Publicado 2021

Multicellular Modelling of Difficult-to-Treat Gastrointestinal Cancers: Current Possibilities and Challenges

por Hakuno, Sarah K., Michiels, Ellis, Kuhlemaijer, Eleonore B., Rooman, Ilse, Hawinkels, Lukas J. A. C., Slingerland, Marije
Publicado 2022

Cystine–glutamate antiporter deletion accelerates motor recovery and improves histological outcomes following spinal cord injury in mice

por Sprimont, Lindsay, Janssen, Pauline, De Swert, Kathleen, Van Bulck, Mathias, Rooman, Ilse, Gilloteaux, Jacques, Massie, Ann, Nicaise, Charles
Publicado 2021

Pancreatic resection with perioperative drug repurposing of propranolol and etodolac: trial protocol of the phase-II randomised placebo controlled PROSPER trial

por Hüttner, Felix J, Rooman, Ilse, Bouche, Gauthier, Knebel, Phillip, Hüsing, Johannes, Mihaljevic, André L, Hackert, Thilo, Strobel, Oliver, Büchler, Markus W, Diener, Markus K
Publicado 2020

ReDO_DB: the repurposing drugs in oncology database

por Pantziarka, Pan, Verbaanderd, Ciska, Sukhatme, Vidula, Rica Capistrano, I, Crispino, Sergio, Gyawali, Bishal, Rooman, Ilse, Van Nuffel, An MT, Meheus, Lydie, Sukhatme, Vikas P, Bouche, Gauthier
Publicado 2018

Pancreas-Specific Sirt1-Deficiency in Mice Compromises Beta-Cell Function without Development of Hyperglycemia

por Pinho, Andreia V., Bensellam, Mohammed, Wauters, Elke, Rees, Maxine, Giry-Laterriere, Marc, Mawson, Amanda, Ly, Le Quan, Biankin, Andrew V., Wu, Jianmin, Laybutt, D. Ross, Rooman, Ilse
Publicado 2015

Pancreatic acinar cell fate relies on system x(C)(-) to prevent ferroptosis during stress

por Pan, Zhaolong, Van den Bossche, Jan-Lars, Rodriguez-Aznar, Eva, Janssen, Pauline, Lara, Olaya, Ates, Gamze, Massie, Ann, De Paep, Diedert Luc, Houbracken, Isabelle, Mambretti, Marco, Rooman, Ilse
Publicado 2023

Sirtuin 1 stimulates the proliferation and the expression of glycolysis genes in pancreatic neoplastic lesions

por Pinho, Andreia V., Mawson, Amanda, Gill, Anthony, Arshi, Mehreen, Warmerdam, Max, Giry-Laterriere, Marc, Eling, Nils, Lie, Triyana, Kuster, Evelyne, Camargo, Simone, Biankin, Andrew V., Wu, Jianmin, Rooman, Ilse
Publicado 2016

MECOM permits pancreatic acinar cell dedifferentiation avoiding cell death under stress conditions

por Backx, Elyne, Wauters, Elke, Baldan, Jonathan, Van Bulck, Mathias, Michiels, Ellis, Heremans, Yves, De Paep, Diedert Luc, Kurokawa, Mineo, Goyama, Susumu, Bouwens, Luc, Jacquemin, Patrick, Houbracken, Isabelle, Rooman, Ilse
Publicado 2021

ROCK signaling promotes collagen remodeling to facilitate invasive pancreatic ductal adenocarcinoma tumor cell growth

por Rath, Nicola, Morton, Jennifer P, Julian, Linda, Helbig, Lena, Kadir, Shereen, McGhee, Ewan J, Anderson, Kurt I, Kalna, Gabriela, Mullin, Margaret, Pinho, Andreia V, Rooman, Ilse, Samuel, Michael S, Olson, Michael F
Publicado 2016

Retinoid Signaling in Pancreatic Cancer, Injury and Regeneration

por Colvin, Emily K., Susanto, Johana M., Kench, James G., Ong, Vivienna N., Mawson, Amanda, Pinese, Mark, Chang, David K., Rooman, Ilse, O'Toole, Sandra A., Segara, Davendra, Musgrove, Elizabeth A., Sutherland, Robert L., Apte, Minoti V., Scarlett, Christopher J., Biankin, Andrew V.
Publicado 2011

ROBO2 is a stroma suppressor gene in the pancreas and acts via TGF-β signalling

por Pinho, Andreia V., Van Bulck, Mathias, Chantrill, Lorraine, Arshi, Mehreen, Sklyarova, Tatyana, Herrmann, David, Vennin, Claire, Gallego-Ortega, David, Mawson, Amanda, Giry-Laterriere, Marc, Magenau, Astrid, Leuckx, Gunther, Baeyens, Luc, Gill, Anthony J., Phillips, Phoebe, Timpson, Paul, Biankin, Andrew V., Wu, Jianmin, Rooman, Ilse
Publicado 2018

Discovery and 3D imaging of a novel ΔNp63-expressing basal cell type in human pancreatic ducts with implications in disease

por Martens, Sandrina, Coolens, Katarina, Van Bulck, Mathias, Arsenijevic, Tatjana, Casamitjana, Joan, Fernandez Ruiz, Angel, El Kaoutari, Abdessamad, Martinez de Villareal, Jaime, Madhloum, Hediel, Esni, Farzad, Heremans, Yves, Leuckx, Gunter, Heimberg, Harry, Bouwens, Luc, Jacquemin, Patrick, De Paep, Diedert Luc, in't Veld, Peter, D'Haene, Nicky, Bouchart, Christelle, Dusetti, Nelson, Van Laethem, Jean-Luc, Waelput, Wim, Lefesvre, Pierre, Real, Francisco X, Rovira, Meritxell, Rooman, Ilse
Publicado 2022