Core Steps of Membrane-Bound Peptidoglycan Biosynthesis: Recent Advances, Insight and Opportunities

por Teo, Alvin C. K., Roper, David I.
Publicado 2015

Prospects for novel inhibitors of peptidoglycan transglycosylases

por Galley, Nicola F., O’Reilly, Amy M., Roper, David I.
Publicado 2014

The pH Dependence of Polymerization and Bundling by the Essential Bacterial Cytoskeltal Protein FtsZ

por Pacheco-Gómez, Raúl, Roper, David I., Dafforn, Timothy R., Rodger, Alison
Publicado 2011

The Extracellular Domain of Two-component System Sensor Kinase VanS from Streptomyces coelicolor Binds Vancomycin at a Newly Identified Binding Site

por Lockey, Christine, Edwards, Richard J., Roper, David I., Dixon, Ann M.
Publicado 2020

The Pneumococcal Divisome: Dynamic Control of Streptococcus pneumoniae Cell Division

por Briggs, Nicholas S., Bruce, Kevin E., Naskar, Souvik, Winkler, Malcolm E., Roper, David I.
Publicado 2021

Investigating the effect of bacteriophages on bacterial FtsZ localisation

por Dhanoa, Gurneet K., Kushnir, Inbar, Qimron, Udi, Roper, David I., Sagona, Antonia P.
Publicado 2022

Expression, purification and crystallization of 2-­oxo-hept-4-ene-1,7-dioate hydratase (HpcG) from Escherichia coli C

por Adachi, Tomoko, Izumi, Atsushi, Rea, Dean, Park, Sam-Yong, Tame, Jeremy R. H., Roper, David I.
Publicado 2006

CO(2) directly modulates connexin 26 by formation of carbamate bridges between subunits

por Meigh, Louise, Greenhalgh, Sophie A, Rodgers, Thomas L, Cann, Martin J, Roper, David I, Dale, Nicholas
Publicado 2013

Plant peptidoglycan precursor biosynthesis: Conservation between moss chloroplasts and Gram-negative bacteria

por Dowson, Amanda J, Lloyd, Adrian J, Cuming, Andrew C, Roper, David I, Frigerio, Lorenzo, Dowson, Christopher G
Publicado 2022

Activator-induced conformational changes regulate division-associated peptidoglycan amidases

por Cook, Jonathan, Baverstock, Tyler C., McAndrew, Martin B. L., Roper, David I., Stansfeld, Phillip J., Crow, Allister
Publicado 2023

The role of the jaw subdomain of peptidoglycan glycosyltransferases for lipid II polymerization

por Punekar, Avinash S., Samsudin, Firdaus, Lloyd, Adrian J., Dowson, Christopher G., Scott, David J., Khalid, Syma, Roper, David I.
Publicado 2018

Insights into bacterial cell division from a structure of EnvC bound to the FtsX periplasmic domain

por Cook, Jonathan, Baverstock, Tyler C., McAndrew, Martin B. L., Stansfeld, Phillip J., Roper, David I., Crow, Allister
Publicado 2020

A Dynamic Network of Proteins Facilitate Cell Envelope Biogenesis in Gram-Negative Bacteria

por Graham, Chris L. B., Newman, Hector, Gillett, Francesca N., Smart, Katie, Briggs, Nicholas, Banzhaf, Manuel, Roper, David I.
Publicado 2021

Nod1 Signaling Overcomes Resistance of S. pneumoniae to Opsonophagocytic Killing

por Lysenko, Elena S, Clarke, Thomas B, Shchepetov, Mikhail, Ratner, Adam J, Roper, David I, Dowson, Christopher G, Weiser, Jeffrey N
Publicado 2007

A conserved zinc-binding site in Acinetobacter baumannii PBP2 required for elongasome-directed bacterial cell shape

por Micelli, Carmina, Dai, Yunfei, Raustad, Nicole, Isberg, Ralph R., Dowson, Christopher G., Lloyd, Adrian J., Geisinger, Edward, Crow, Allister, Roper, David I.
Publicado 2023

Reconstruction of diaminopimelic acid biosynthesis allows characterisation of Mycobacterium tuberculosis N-succinyl-L,L-diaminopimelic acid desuccinylase

por Usha, Veeraraghavan, Lloyd, Adrian J., Roper, David I., Dowson, Christopher G., Kozlov, Guennadi, Gehring, Kalle, Chauhan, Smita, Imam, Hasan T., Blindauer, Claudia A., Besra, Gurdyal S.
Publicado 2016

A molecular link between cell wall biosynthesis, translation fidelity, and stringent response in Streptococcus pneumoniae

por Aggarwal, Surya D., Lloyd, Adrian J., Yerneni, Saigopalakrishna S., Narciso, Ana Rita, Shepherd, Jennifer, Roper, David I., Dowson, Christopher G., Filipe, Sergio R., Hiller, N. Luisa
Publicado 2021

Anticancer metallohelices: nanomolar potency and high selectivity

por Kaner, Rebecca A., Allison, Simon J., Faulkner, Alan D., Phillips, Roger M., Roper, David I., Shepherd, Samantha L., Simpson, Daniel H., Waterfield, Nicholas R., Scott, Peter
Publicado 2016

Structure-based modeling and dynamics of MurM, a Streptococcus pneumoniae penicillin resistance determinant present at the cytoplasmic membrane

por York, Anna, Lloyd, Adrian.J., del Genio, Charo I., Shearer, Jonathan, Hinxman, Karen.J., Fritz, Konstantin, Fulop, Vilmos, Dowson, Christopher.G., Khalid, Syma, Roper, David.I.
Publicado 2021

In vitro characterization of the antivirulence target of Gram-positive pathogens, peptidoglycan O-acetyltransferase A (OatA)

por Sychantha, David, Jones, Carys S., Little, Dustin J., Moynihan, Patrick J., Robinson, Howard, Galley, Nicola F., Roper, David I., Dowson, Christopher G., Howell, P. Lynne, Clarke, Anthony J.
Publicado 2017