The power of comparative and developmental studies for mouse models of Down syndrome

por Moore, Clara S., Roper, Randall J.
Publicado 2007

Understanding the Basis for Down Syndrome Phenotypes

por Roper, Randall J, Reeves, Roger H
Publicado 2006

Targeting trisomic treatments: optimizing Dyrk1a inhibition to improve Down syndrome deficits

por Stringer, Megan, Goodlett, Charles R., Roper, Randall J.
Publicado 2017

Skeletal Deficits in Male and Female down Syndrome Model Mice Arise Independent of Normalized Dyrk1a Expression in Osteoblasts

por Thomas, Jared R., Sloan, Kourtney, Cave, Kelsey, Wallace, Joseph M., Roper, Randall J.
Publicado 2021

Evaluation of the therapeutic potential of Epigallocatechin-3-gallate (EGCG) via oral gavage in young adult Down syndrome mice

por Goodlett, Charles R., Stringer, Megan, LaCombe, Jonathan, Patel, Roshni, Wallace, Joseph M., Roper, Randall J.
Publicado 2020

Increased dosage and treatment time of Epigallocatechin-3-gallate (EGCG) negatively affects skeletal parameters in normal mice and Down syndrome mouse models

por Jamal, Raza, LaCombe, Jonathan, Patel, Roshni, Blackwell, Matthew, Thomas, Jared R., Sloan, Kourtney, Wallace, Joseph M., Roper, Randall J.
Publicado 2022

Interaction of sexual dimorphism and gene dosage imbalance in skeletal deficits associated with Down syndrome

por Thomas, Jared R., LaCombe, Jonathan, Long, Rachel, Lana-Elola, Eva, Watson-Scales, Sheona, Wallace, Joseph M., Fisher, Elizabeth M.C., Tybulewicz, Victor L.J., Roper, Randall J.
Publicado 2020

Genetic dissection of triplicated chromosome 21 orthologs yields varying skeletal traits in Down syndrome model mice

por Sloan, Kourtney, Thomas, Jared, Blackwell, Matthew, Voisard, Deanna, Lana-Elola, Eva, Watson-Scales, Sheona, Roper, Daniel L., Wallace, Joseph M., Fisher, Elizabeth M. C., Tybulewicz, Victor L. J., Roper, Randall J.
Publicado 2023

Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome

por Fulton, Sasha L., Wenderski, Wendy, Lepack, Ashley E., Eagle, Andrew L., Fanutza, Tomas, Bastle, Ryan M., Ramakrishnan, Aarthi, Hays, Emma C., Neal, Arianna, Bendl, Jaroslav, Farrelly, Lorna A., Al-Kachak, Amni, Lyu, Yang, Cetin, Bulent, Chan, Jennifer C., Tran, Tina N., Neve, Rachael L., Roper, Randall J., Brennand, Kristen J., Roussos, Panos, Schimenti, John C., Friedman, Allyson K., Shen, Li, Blitzer, Robert D., Robison, Alfred J., Crabtree, Gerald R., Maze, Ian
Publicado 2022