Orexin-1 and orexin-2 receptor antagonists reduce ethanol self-administration in high-drinking rodent models

por Anderson, Rachel I., Becker, Howard C., Adams, Benjamin L., Jesudason, Cynthia D., Rorick-Kehn, Linda M.
Publicado 2014

LSN2424100: a novel, potent orexin-2 receptor antagonist with selectivity over orexin-1 receptors and activity in an animal model predictive of antidepressant-like efficacy

por Fitch, Thomas E., Benvenga, Mark J., Jesudason, Cynthia D., Zink, Charity, Vandergriff, Amy B., Menezes, Michelle M., Schober, Douglas A., Rorick-Kehn, Linda M.
Publicado 2014

Determining Pharmacological Selectivity of the Kappa Opioid Receptor Antagonist LY2456302 Using Pupillometry as a Translational Biomarker in Rat and Human

por Rorick-Kehn, Linda M., Witcher, Jennifer W., Lowe, Stephen L., Gonzales, Celedon R., Weller, Mary Ann, Bell, Robert L., Hart, John C., Need, Anne B., McKinzie, Jamie H., Statnick, Michael A., Suico, Jeffrey G., McKinzie, David L., Tauscher-Wisniewski, Sitra, Mitch, Charles H., Stoltz, Randall R., Wong, Conrad J.
Publicado 2015

Preclinical findings predicting efficacy and side‐effect profile of LY2940094, an antagonist of nociceptin receptors

por Witkin, Jeffrey M., Rorick‐Kehn, Linda M., Benvenga, Mark J., Adams, Benjamin L., Gleason, Scott D., Knitowski, Karen M., Li, Xia, Chaney, Steven, Falcone, Julie F., Smith, Janice W., Foss, Julie, Lloyd, Kirsti, Catlow, John T., McKinzie, David L., Svensson, Kjell A., Barth, Vanessa N., Toledo, Miguel A., Diaz, Nuria, Lafuente, Celia, Jiménez, Alma, Benito, Alfonso, Pedregal, Conception, Martínez‐Grau, Maria A., Post, Anke, Ansonoff, Michael A., Pintar, John E., Statnick, Michael A.
Publicado 2016