Mechanism of allosteric activation of TMEM16A/ANO1 channels by a commonly used chloride channel blocker

por Ta, Chau M, Adomaviciene, Aiste, Rorsman, Nils J G, Garnett, Hannah, Tammaro, Paolo
Publicado 2016

Defining the ionic mechanisms of optogenetic control of vascular tone by channelrhodopsin‐2

por Rorsman, Nils J G, Ta, Chau M, Garnett, Hannah, Swietach, Pawel, Tammaro, Paolo
Publicado 2018

Contrasting effects of phosphatidylinositol 4,5‐bisphosphate on cloned TMEM16A and TMEM16B channels

por Ta, Chau M, Acheson, Kathryn E, Rorsman, Nils J G, Jongkind, Remco C, Tammaro, Paolo
Publicado 2017

CPT1a-Dependent Long-Chain Fatty Acid Oxidation Contributes to Maintaining Glucagon Secretion from Pancreatic Islets

por Briant, Linford J.B., Dodd, Michael S., Chibalina, Margarita V., Rorsman, Nils J.G., Johnson, Paul R.V., Carmeliet, Peter, Rorsman, Patrik, Knudsen, Jakob G.
Publicado 2018

Reduced somatostatin signalling leads to hypersecretion of glucagon in mice fed a high-fat diet

por Kellard, Joely A., Rorsman, Nils J.G., Hill, Thomas G., Armour, Sarah L., van de Bunt, Martijn, Rorsman, Patrik, Knudsen, Jakob G., Briant, Linford J.B.
Publicado 2020

Na(+) current properties in islet α- and β-cells reflect cell-specific Scn3a and Scn9a expression

por Zhang, Quan, Chibalina, Margarita V, Bengtsson, Martin, Groschner, Lukas N, Ramracheya, Reshma, Rorsman, Nils J G, Leiss, Veronika, Nassar, Mohammed A, Welling, Andrea, Gribble, Fiona M, Reimann, Frank, Hofmann, Franz, Wood, John N, Ashcroft, Frances M, Rorsman, Patrik
Publicado 2014

Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion

por Vergari, Elisa, Knudsen, Jakob G., Ramracheya, Reshma, Salehi, Albert, Zhang, Quan, Adam, Julie, Asterholm, Ingrid Wernstedt, Benrick, Anna, Briant, Linford J. B., Chibalina, Margarita V., Gribble, Fiona M., Hamilton, Alexander, Hastoy, Benoit, Reimann, Frank, Rorsman, Nils J. G., Spiliotis, Ioannis I., Tarasov, Andrei, Wu, Yanling, Ashcroft, Frances M., Rorsman, Patrik
Publicado 2019

Somatostatin secretion by Na(+)-dependent Ca(2+)-induced Ca(2+) release in pancreatic delta-cells

por Vergari, Elisa, Denwood, Geoffrey, Salehi, Albert, Zhang, Quan, Adam, Julie, Alrifaiy, Ahmed, Wernstedt Asterholm, Ingrid, Benrick, Anna, Chibalina, Margarita V., Eliasson, Lena, Guida, Claudia, Hill, Thomas G., Hamilton, Alexander, Ramracheya, Reshma, Reimann, Frank, Rorsman, Nils J. G., Spilliotis, Ioannis, Tarasov, Andrei I., Walker, Jonathan N., Rorsman, Patrik, Briant, Linford J. B.
Publicado 2020

Role of K(ATP) Channels in Glucose-Regulated Glucagon Secretion and Impaired Counterregulation in Type 2 Diabetes

por Zhang, Quan, Ramracheya, Reshma, Lahmann, Carolina, Tarasov, Andrei, Bengtsson, Martin, Braha, Orit, Braun, Matthias, Brereton, Melissa, Collins, Stephan, Galvanovskis, Juris, Gonzalez, Alejandro, Groschner, Lukas N., Rorsman, Nils J.G., Salehi, Albert, Travers, Mary E., Walker, Jonathan N., Gloyn, Anna L., Gribble, Fiona, Johnson, Paul R.V., Reimann, Frank, Ashcroft, Frances M., Rorsman, Patrik
Publicado 2013

The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K

por Bushell, Simon R., Pike, Ashley C. W., Falzone, Maria E., Rorsman, Nils J. G., Ta, Chau M., Corey, Robin A., Newport, Thomas D., Christianson, John C., Scofano, Lara F., Shintre, Chitra A., Tessitore, Annamaria, Chu, Amy, Wang, Qinrui, Shrestha, Leela, Mukhopadhyay, Shubhashish M. M., Love, James D., Burgess-Brown, Nicola A., Sitsapesan, Rebecca, Stansfeld, Phillip J., Huiskonen, Juha T., Tammaro, Paolo, Accardi, Alessio, Carpenter, Elisabeth P.
Publicado 2019

Fumarate Hydratase Deletion in Pancreatic β Cells Leads to Progressive Diabetes

por Adam, Julie, Ramracheya, Reshma, Chibalina, Margarita V., Ternette, Nicola, Hamilton, Alexander, Tarasov, Andrei I., Zhang, Quan, Rebelato, Eduardo, Rorsman, Nils J.G., Martín-del-Río, Rafael, Lewis, Amy, Özkan, Gizem, Do, Hyun Woong, Spégel, Peter, Saitoh, Kaori, Kato, Keiko, Igarashi, Kaori, Kessler, Benedikt M., Pugh, Christopher W., Tamarit-Rodriguez, Jorge, Mulder, Hindrik, Clark, Anne, Frizzell, Norma, Soga, Tomoyoshi, Ashcroft, Frances M., Silver, Andrew, Pollard, Patrick J., Rorsman, Patrik
Publicado 2017