Altered acetyl-CoA metabolism presents a new potential immunotherapy target in the obese lung microenvironment

por Rosario, Spencer R., Smith, Randall J., Patnaik, Santosh K., Liu, Song, Barbi, Joseph, Yendamuri, Sai
Publicado 2022

Pan-cancer molecular analysis of the RB tumor suppressor pathway

por Knudsen, Erik S., Nambiar, Ram, Rosario, Spencer R., Smiraglia, Dominic J., Goodrich, David W., Witkiewicz, Agnieszka K.
Publicado 2020

JAZF1: A Metabolic Regulator of Sensitivity to a Polyamine-Targeted Therapy

por Rosario, Spencer R., Jacobi, Justine J., Long, Mark D., Affronti, Hayley C., Rowsam, Aryn M., Smiraglia, Dominic J.
Publicado 2023

HotSPOT: A Computational Tool to Design Targeted Sequencing Panels to Assess Early Photocarcinogenesis

por Grant, Sydney R., Rosario, Spencer R., Patentreger, Andrew D., Shary, Nico, Fitzgerald, Megan E., Singh, Prashant K., Foster, Barbara A., Huss, Wendy J., Wei, Lei, Paragh, Gyorgy
Publicado 2023

BiTE secretion by adoptively transferred stem-like T cells improves FRα+ ovarian cancer control

por McGray, A J Robert, Chiello, Jessie L, Tsuji, Takemasa, Long, Mark, Maraszek, Kathryn, Gaulin, Nicole, Rosario, Spencer R, Hess, Suzanne M, Abrams, Scott I, Kozbor, Danuta, Odunsi, Kunle, Zsiros, Emese
Publicado 2023

Combined BRCA2 and MAGEC3 Expression Predict Outcome in Advanced Ovarian Cancers

por Omole, Emmanuel B., Aijaz, Iqbal, Ellegate, James, Isenhart, Emily, Desouki, Mohamed M., Mastri, Michalis, Humphrey, Kristen, Dougherty, Emily M., Rosario, Spencer R., Nastiuk, Kent L., Ohm, Joyce E., Eng, Kevin H.
Publicado 2022

Hypoxic activation of PFKFB4 in breast tumor microenvironment shapes metabolic and cellular plasticity to accentuate metastatic competence

por Dai, Tao, Rosario, Spencer R., Katsuta, Eriko, Dessai, Abhisha Sawant, Paterson, Emily J., Novickis, Aaron T., Cortes Gomez, Eduardo, Zhu, Bokai, Liu, Song, Wang, Hai, Abrams, Scott I., Seshadri, Mukund, Bshara, Wiam, Dasgupta, Subhamoy
Publicado 2022

Dietary folate levels alter the kinetics and molecular mechanism of prostate cancer recurrence in the CWR22 model

por Affronti, Hayley C., Long, Mark D., Rosario, Spencer R., Gillard, Bryan M., Karasik, Ellen, Boerlin, Christoph S., Pellerite, Anthony J., Foster, Barbara A., Attwood, Kristopher, Pili, Roberto, Wilton, John H., Campbell, Moray J., Smiraglia, Dominic J.
Publicado 2017

Reduced NCOR2 expression accelerates androgen deprivation therapy failure in prostate cancer

por Long, Mark D., Jacobi, Justine J., Singh, Prashant K., Llimos, Gerard, Wani, Sajad A., Rowsam, Aryn M., Rosario, Spencer R., Hoogstraat, Marlous, Linder, Simon, Kirk, Jason, Affronti, Hayley C., Bergman, Andries, Zwart, Wilbert, Campbell, Moray J., Smiraglia, Dominic J.
Publicado 2021

Pharmacological polyamine catabolism upregulation with methionine salvage pathway inhibition as an effective prostate cancer therapy

por Affronti, Hayley C., Rowsam, Aryn M., Pellerite, Anthony J., Rosario, Spencer R., Long, Mark D., Jacobi, Justine J., Bianchi-Smiraglia, Anna, Boerlin, Christoph S., Gillard, Bryan M., Karasik, Ellen, Foster, Barbara A., Moser, Michael, Wilton, John H., Attwood, Kristopher, Nikiforov, Mikhail A., Azabdaftari, Gissou, Pili, Roberto, Phillips, James G., Casero, Robert A., Smiraglia, Dominic J.
Publicado 2020

Metabolic Dysregulation Explains the Diverse Impacts of Obesity in Males and Females with Gastrointestinal Cancers

por Rosario, Spencer R., Dong, Bowen, Zhang, Yali, Hsiao, Hua-Hsin, Isenhart, Emily, Wang, Jianmin, Siegel, Erin M., Monjazeb, Arta M., Owen, Dwight H., Dey, Prasenjit, Tabung, Fred K., Spakowicz, Daniel J., Murphy, William J., Edge, Stephen, Yendamuri, Sai, Ibrahimi, Sami, Kolesar, Jill M., McDonald, Patsy H., Vadehra, Deepak, Churchman, Michelle, Liu, Song, Kalinski, Pawel, Mukherjee, Sarbajit
Publicado 2023