Chaperone mediated detection of small molecule target binding in cells

por Cho, Kelvin F., Ma, Taylur P., Rose, Christopher M., Kirkpatrick, Donald S., Yu, Kebing, Blake, Robert A.
Publicado 2020

Sensitive and Quantitative Detection of MHC-I Displayed Neoepitopes Using a Semiautomated Workflow and TOMAHAQ Mass Spectrometry

por Pollock, Samuel B., Rose, Christopher M., Darwish, Martine, Bouziat, Romain, Delamarre, Lélia, Blanchette, Craig, Lill, Jennie R.
Publicado 2021

Medicago PhosphoProtein Database: a repository for Medicago truncatula phosphoprotein data

por Rose, Christopher M., Venkateshwaran, Muthusubramanian, Grimsrud, Paul A., Westphall, Michael S., Sussman, Michael R., Coon, Joshua J., Ané, Jean-Michel
Publicado 2012

Stress‐induced vesicular assemblies of dual leucine zipper kinase are signaling hubs involved in kinase activation and neurodegeneration

por Tortosa, Elena, Sengupta Ghosh, Arundhati, Li, Qingling, Wong, Weng Ruh, Hinkle, Trent, Sandoval, Wendy, Rose, Christopher M, Hoogenraad, Casper C
Publicado 2022

Chronic platelet-derived growth factor receptor signaling exerts control over initiation of protein translation in glioma

por Zhou, Shuang, Appleman, Vicky A, Rose, Christopher M, Jun, Hyun Jung, Yang, Juechen, Zhou, Yue, Bronson, Roderick T, Gygi, Steve P, Charest, Al
Publicado 2018

AzidoTMT Enables Direct Enrichment and Highly Multiplexed Quantitation of Proteome-Wide Functional Residues

por Ma, Taylur P., Izrael-Tomasevic, Anita, Mroue, Rana, Budayeva, Hanna, Malhotra, Sushant, Raisner, Ryan, Evangelista, Marie, Rose, Christopher M., Kirkpatrick, Donald S., Yu, Kebing
Publicado 2023

F-box Protein FBXL16 Binds PP2A-B55α and Regulates Differentiation of Embryonic Stem Cells along the FLK1+ Lineage

por Honarpour, Narimon, Rose, Christopher M., Brumbaugh, Justin, Anderson, Jody, Graham, Robert L. J., Sweredoski, Michael J., Hess, Sonja, Coon, Joshua J., Deshaies, Raymond J.
Publicado 2014

Compositional Proteomics: Effects of Spatial Constraints on Protein Quantification Utilizing Isobaric Tags

por O’Brien, Jonathon J., O’Connell, Jeremy D., Paulo, Joao A., Thakurta, Sanjukta, Rose, Christopher M., Weekes, Michael P., Huttlin, Edward L., Gygi, Steven P.
Publicado 2017

Polarized microtubule remodeling transforms the morphology of reactive microglia and drives cytokine release

por Adrian, Max, Weber, Martin, Tsai, Ming-Chi, Glock, Caspar, Kahn, Olga I., Phu, Lilian, Cheung, Tommy K., Meilandt, William J., Rose, Christopher M., Hoogenraad, Casper C.
Publicado 2023

Neutron-Encoded Mass Signatures for Quantitative Top-Down Proteomics∥

por Rhoads, Timothy W., Rose, Christopher M., Bailey, Derek J., Riley, Nicholas M., Molden, Rosalynn C., Nestler, Amelia J., Merrill, Anna E., Smith, Lloyd M., Hebert, Alexander S., Westphall, Michael S., Pagliarini, David J., Garcia, Benjamin A., Coon, Joshua J.
Publicado 2014

Transposable element expression in tumors is associated with immune infiltration and increased antigenicity

por Kong, Yu, Rose, Christopher M., Cass, Ashley A., Williams, Alexander G., Darwish, Martine, Lianoglou, Steve, Haverty, Peter M., Tong, Ann-Jay, Blanchette, Craig, Albert, Matthew L., Mellman, Ira, Bourgon, Richard, Greally, John, Jhunjhunwala, Suchit, Chen-Harris, Haiyin
Publicado 2019

Driver Mutations Dictate the Immunologic Landscape and Response to Checkpoint Immunotherapy of Glioblastoma

por Yeo, Alan T., Shah, Rushil, Aliazis, Konstantinos, Pal, Rinku, Xu, Tuoye, Zhang, Piyan, Rawal, Shruti, Rose, Christopher M., Varn, Frederick S., Appleman, Vicky A., Yoon, Joon, Varma, Hemant, Gygi, Steven P., Verhaak, Roel G.W., Boussiotis, Vassiliki A., Charest, Al
Publicado 2023

Antibody toolkit reveals N-terminally ubiquitinated substrates of UBE2W

por Davies, Christopher W., Vidal, Simon E., Phu, Lilian, Sudhamsu, Jawahar, Hinkle, Trent B., Chan Rosenberg, Scott, Schumacher, Frances-Rose, Zeng, Yi Jimmy, Schwerdtfeger, Carsten, Peterson, Andrew S., Lill, Jennie R., Rose, Christopher M., Shaw, Andrey S., Wertz, Ingrid E., Kirkpatrick, Donald S., Koerber, James T.
Publicado 2021

A PDGFRα-driven mouse model of glioblastoma reveals a stathmin1-mediated mechanism of sensitivity to vinblastine

por Jun, Hyun Jung, Appleman, Vicky A., Wu, Hua-Jun, Rose, Christopher M., Pineda, Javier J., Yeo, Alan T., Delcuze, Bethany, Lee, Charlotte, Gyuris, Aron, Zhu, Haihao, Woolfenden, Steve, Bronisz, Agnieszka, Nakano, Ichiro, Chiocca, Ennio A., Bronson, Roderick T., Ligon, Keith L., Sarkaria, Jann N., Gygi, Steve P., Michor, Franziska, Mitchison, Timothy J., Charest, Al
Publicado 2018

Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer’s disease mouse models

por Dejanovic, Borislav, Wu, Tiffany, Tsai, Ming-Chi, Graykowski, David, Gandham, Vineela D., Rose, Christopher M., Bakalarski, Corey E., Ngu, Hai, Wang, Yuanyuan, Pandey, Shristi, Rezzonico, Mitchell G., Friedman, Brad A., Edmonds, Rose, De Mazière, Ann, Rakosi-Schmidt, Raphael, Singh, Tarjinder, Klumperman, Judith, Foreman, Oded, Chang, Michael C., Xie, Luke, Sheng, Morgan, Hanson, Jesse E.
Publicado 2022

An RNA Damage Response Network Mediates the Lethality of 5-FU in Clinically Relevant Tumor Types

por Chen, Jung-Kuei, Merrick, Karl A., Kong, Yi Wen, Izrael-Tomasevic, Anita, Eng, George, Handly, Erika D., Patterson, Jesse C., Cannell, Ian G., Suarez-Lopez, Lucia, Hosios, Aaron M., Dinh, Anh, Kirkpatrick, Donald S., Yu, Kebing, Rose, Christopher M., Hernandez, Jonathan M., Hwangbo, Haeun, Palmer, Adam C., Vander Heiden, Matthew G., Yilmaz, Ömer H., Yaffe, Michael B.
Publicado 2023

TMEM106B reduction does not rescue GRN deficiency in iPSC-derived human microglia and mouse models

por Dominguez, Sara L., Laufer, Benjamin I., Ghosh, Arundhati Sengupta, Li, Qingling, Ruggeri, Gaia, Emani, Maheswara Reddy, Phu, Lilian, Friedman, Brad A., Sandoval, Wendy, Rose, Christopher M., Ngu, Hai, Foreman, Oded, Reichelt, Mike, Juste, Yves, Lalehzadeh, Guita, Hansen, Dennis, Nymark, Helle, Mellal, Denia, Gylling, Helene, Kiełpiński, Łukasz J., Chih, Ben, Bingol, Baris, Hoogenraad, Casper C., Meilandt, William J., Easton, Amy
Publicado 2023

PTP1B regulates non-mitochondrial oxygen consumption via RNF213 to promote tumour survival during hypoxia

por Banh, Robert S., Iorio, Caterina, Marcotte, Richard, Xu, Yang, Cojocari, Dan, Rahman, Anas Abdel, Pawling, Judy, Zhang, Wei, Sinha, Ankit, Rose, Christopher M., Isasa, Marta, Zhang, Shuang, Wu, Ronald, Virtanen, Carl, Hitomi, Toshiaki, Habu, Toshiyuki, Sidhu, Sachdev S., Koizumi, Akio, Wilkins, Sarah E., Kislinger, Thomas, Gygi, Steven P., Schofield, Christopher J., Dennis, James W., Wouters, Bradly G., Neel, Benjamin G.
Publicado 2016

Selective PROTAC-mediated degradation of SMARCA2 is efficacious in SMARCA4 mutant cancers

por Cantley, Jennifer, Ye, Xiaofen, Rousseau, Emma, Januario, Tom, Hamman, Brian D., Rose, Christopher M., Cheung, Tommy K., Hinkle, Trent, Soto, Leofal, Quinn, Connor, Harbin, Alicia, Bortolon, Elizabeth, Chen, Xin, Haskell, Roy, Lin, Eva, Yu, Shang-Fan, Del Rosario, Geoff, Chan, Emily, Dunlap, Debra, Koeppen, Hartmut, Martin, Scott, Merchant, Mark, Grimmer, Matt, Broccatelli, Fabio, Wang, Jing, Pizzano, Jennifer, Dragovich, Peter S., Berlin, Michael, Yauch, Robert L.
Publicado 2022