PARP Inhibitors: Clinical Relevance, Mechanisms of Action and Tumor Resistance

por Rose, Maddison, Burgess, Joshua T., O’Byrne, Kenneth, Richard, Derek J., Bolderson, Emma
Publicado 2020

The role of inner nuclear membrane proteins in tumourigenesis and as potential targets for cancer therapy

por Rose, Maddison, Burgess, Joshua T., O’Byrne, Kenneth, Richard, Derek J., Bolderson, Emma
Publicado 2022

Cell Metabolism and DNA Repair Pathways: Implications for Cancer Therapy

por Sobanski, Thais, Rose, Maddison, Suraweera, Amila, O’Byrne, Kenneth, Richard, Derek J., Bolderson, Emma
Publicado 2021

The Therapeutic Potential of DNA Damage Repair Pathways and Genomic Stability in Lung Cancer

por Burgess, Joshua T., Rose, Maddison, Boucher, Didier, Plowman, Jennifer, Molloy, Christopher, Fisher, Mark, O'Leary, Connor, Richard, Derek J., O'Byrne, Kenneth J., Bolderson, Emma
Publicado 2020

The fructose-bisphosphate, Aldolase A (ALDOA), facilitates DNA-PKcs and ATM kinase activity to regulate DNA double-strand break repair

por Sobanski, Thais, Suraweera, Amila, Burgess, Joshua T., Richard, Iain, Cheong, Chee Man, Dave, Keyur, Rose, Maddison, Adams, Mark N., O’Byrne, Kenneth J., Richard, Derek J., Bolderson, Emma
Publicado 2023

The Impact of Rare Human Variants on Barrier-To-Auto-Integration Factor 1 (Banf1) Structure and Function

por Rose, Maddison, Bai, Bond, Tang, Ming, Cheong, Chee Man, Beard, Sam, Burgess, Joshua T., Adams, Mark N., O’Byrne, Kenneth J., Richard, Derek J., Gandhi, Neha S., Bolderson, Emma
Publicado 2021

Barrier-to-autointegration-factor (Banf1) modulates DNA double-strand break repair pathway choice via regulation of DNA-dependent kinase (DNA-PK) activity

por Burgess, Joshua T, Cheong, Chee Man, Suraweera, Amila, Sobanski, Thais, Beard, Sam, Dave, Keyur, Rose, Maddison, Boucher, Didier, Croft, Laura V, Adams, Mark N, O’Byrne, Kenneth, Richard, Derek J, Bolderson, Emma
Publicado 2021