EMBR-07. MYC BUT NOT MYCN GENERATES AGGRESSIVE GROUP 3 MEDULLOBLASTOMA BY ARF PATHWAY SUPPRESSION

por Mainwaring, Oliver, Weishaupt, Holger, Hutter, Sonja, Zhao, Miao, Rosén, Gabriela, Breinschmid, Laura, Verbaan, Annemieke, Sundström, Anders, Annusver, Karl, Kasper, Maria, Swartling, Fredrik
Publicado 2021

Profiling chromatin accessibility in formalin-fixed paraffin-embedded samples

por Zhang, Hua, Polavarapu, Vamsi Krishna, Xing, Pengwei, Zhao, Miao, Mathot, Lucy, Zhao, Linxuan, Rosen, Gabriela, Swartling, Fredrik J., Sjöblom, Tobias, Chen, Xingqi
Publicado 2022

MEDB-55. Single-cell transcriptomics reveals progenitor cells expressing a photoreceptor program as putative cells origin of MYC-driven Group 3 Medulloblastoma

por Zhao, Miao, Mainwaring, Oliver, Rosén, Gabriela, Elgendy, Ramy, Doroszko, Milena, Rijpkema, Sanne, Sundstrom, Anders, Nelander, Sven, Weishaupt, Holger, Furukawa, Takahisa, Swartling, Fredrik J
Publicado 2022

BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells

por Čančer, Matko, Drews, Lisa F., Bengtsson, Johan, Bolin, Sara, Rosén, Gabriela, Westermark, Bengt, Nelander, Sven, Forsberg-Nilsson, Karin, Uhrbom, Lene, Weishaupt, Holger, Swartling, Fredrik J.
Publicado 2019

BIOL-15. PATIENT-DERIVED XENOGRAFTS OF MATCHED PRIMARY-RECURRENT PEDIATRIC BRAIN TUMORS AS A RESOURCE FOR IDENTIFYING THERAPY RESISTANCE PROFILES

por Zhao, Miao, Olsen, Thale, Bergström, Tobias, Rosén, Gabriela, Dalmo, Erika, Vikström, Elin, Larsson, Ida, Lin, Tina, Sundström, Anders, Holmberg, Karl, Weishaupt, Holger, Nelander, Sven, Giraud, Geraldine, Swartling, Fredrik
Publicado 2023

Novel cancer gene discovery using a forward genetic screen in RCAS-PDGFB-driven gliomas

por Weishaupt, Holger, Čančer, Matko, Rosén, Gabriela, Holmberg, Karl O, Häggqvist, Susana, Bunikis, Ignas, Jiang, Yiwen, Sreedharan, Smitha, Gyllensten, Ulf, Becher, Oren J, Uhrbom, Lene, Ameur, Adam, Swartling, Fredrik J
Publicado 2022

Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy

por Čančer, Matko, Hutter, Sonja, Holmberg, Karl O., Rosén, Gabriela, Sundström, Anders, Tailor, Jignesh, Bergström, Tobias, Garancher, Alexandra, Essand, Magnus, Wechsler-Reya, Robert J., Falk, Anna, Weishaupt, Holger, Swartling, Fredrik J.
Publicado 2019

ARF suppression by MYC but not MYCN confers increased malignancy of aggressive pediatric brain tumors

por Mainwaring, Oliver J., Weishaupt, Holger, Zhao, Miao, Rosén, Gabriela, Borgenvik, Anna, Breinschmid, Laura, Verbaan, Annemieke D., Richardson, Stacey, Thompson, Dean, Clifford, Steven C., Hill, Rebecca M., Annusver, Karl, Sundström, Anders, Holmberg, Karl O., Kasper, Maria, Hutter, Sonja, Swartling, Fredrik J.
Publicado 2023

FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma

por Suryo Rahmanto, Aldwin, Savov, Vasil, Brunner, Andrä, Bolin, Sara, Weishaupt, Holger, Malyukova, Alena, Rosén, Gabriela, Čančer, Matko, Hutter, Sonja, Sundström, Anders, Kawauchi, Daisuke, Jones, David TW, Spruck, Charles, Taylor, Michael D, Cho, Yoon‐Jae, Pfister, Stefan M, Kool, Marcel, Korshunov, Andrey, Swartling, Fredrik J, Sangfelt, Olle
Publicado 2016

MBRS-10. QUIESCENT SOX9-POSITIVE CELLS BEHIND MYC DRIVEN MEDULLOBLASTOMA RECURRENCE

por Bolin, Sara, Savov, Vasil, Borgenvik, Anna, Rosén, Gabriela, Olausson, Karl Holmberg, Zhao, Miao, Garancher, Alexandra, Rahmanto, Aldwin Suryo, Hutter, Sonja, Mainwaring, Oliver, Rusert, Jessica, Sundstrom, Anders, Richardson, Stacey, Fotaki, Grammatiki, Hill, Rebecca M, Dubuc, Adrian M, Kalushkova, Antonia, Remke, Marc, Čančer, Matko, Jernberg-Wiklund, Helena, Ramaswamy, Vijay, Chen, Xingqi, Taylor, Michael D, Sangfelt, Olle, Schüller, Ulrich, Clifford, Steve C, Wechsler-Reya, Robert J, Weishaupt, Holger, Swartling, Fredrik J
Publicado 2020

Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma

por Borgenvik, Anna, Holmberg, Karl O., Bolin, Sara, Zhao, Miao, Savov, Vasil, Rosén, Gabriela, Hutter, Sonja, Garancher, Alexandra, Rahmanto, Aldwin Suryo, Bergström, Tobias, Olsen, Thale Kristin, Mainwaring, Oliver J., Sattanino, Damiana, Verbaan, Annemieke D., Rusert, Jessica M., Sundström, Anders, Bravo, Mar Ballester, Dang, Yonglong, Wenz, Amelie S., Richardson, Stacey, Fotaki, Grammatiki, Hill, Rebecca M., Dubuc, Adrian M., Kalushkova, Antonia, Remke, Marc, Čančer, Matko, Jernberg-Wiklund, Helena, Giraud, Géraldine, Chen, Xingqi, Taylor, Michael D., Sangfelt, Olle, Clifford, Steven C., Schüller, Ulrich, Wechsler-Reya, Robert J., Weishaupt, Holger, Swartling, Fredrik J.
Publicado 2022