Targeting Progranulin as an Immuno-Neurology Therapeutic Approach

por Boylan, Maria A., Pincetic, Andrew, Romano, Gary, Tatton, Nadine, Kenkare-Mitra, Sara, Rosenthal, Arnon
Publicado 2023

Passive immunotherapy against Aβ in aged APP-transgenic mice reverses cognitive deficits and depletes parenchymal amyloid deposits in spite of increased vascular amyloid and microh...

por Wilcock, Donna M, Rojiani, Amyn, Rosenthal, Arnon, Subbarao, Sangeetha, Freeman, Melissa J, Gordon, Marcia N, Morgan, Dave
Publicado 2004

Latozinemab, a novel progranulin-elevating therapy for frontotemporal dementia

por Kurnellas, Michael, Mitra, Ananya, Schwabe, Tina, Paul, Robert, Arrant, Andrew E., Roberson, Erik D., Ward, Michael, Yeh, Felix, Long, Hua, Rosenthal, Arnon
Publicado 2023

Intracranial administration of deglycosylated C-terminal-specific anti-Aβ antibody efficiently clears amyloid plaques without activating microglia in amyloid-depositing transgenic...

por Carty, Niki C, Wilcock, Donna M, Rosenthal, Arnon, Grimm, Jan, Pons, Jaume, Ronan, Victoria, Gottschall, Paul E, Gordon, Marcia N, Morgan, Dave
Publicado 2006

Anti-human TREM2 induces microglia proliferation and reduces pathology in an Alzheimer’s disease model

por Wang, Shoutang, Mustafa, Meer, Yuede, Carla M., Salazar, Santiago Viveros, Kong, Philip, Long, Hua, Ward, Michael, Siddiqui, Omer, Paul, Robert, Gilfillan, Susan, Ibrahim, Adiljan, Rhinn, Hervé, Tassi, Ilaria, Rosenthal, Arnon, Schwabe, Tina, Colonna, Marco
Publicado 2020

Appetite Enhancement and Weight Gain by Peripheral Administration of TrkB Agonists in Non-Human Primates

por Lin, John C., Tsao, David, Barras, Paul, Bastarrachea, Raul A., Boyd, Bob, Chou, Joyce, Rosete, Rodnie, Long, Hua, Forgie, Alison, Abdiche, Yasmina, Dilley, Jeanette, Stratton, Jennifer, Garcia, Carlos, Sloane, David L., Comuzzie, Anthony G., Rosenthal, Arnon
Publicado 2008

TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis

por Cignarella, Francesca, Filipello, Fabia, Bollman, Bryan, Cantoni, Claudia, Locca, Alberto, Mikesell, Robert, Manis, Melissa, Ibrahim, Adiljan, Deng, Li, Benitez, Bruno A., Cruchaga, Carlos, Licastro, Danilo, Mihindukulasuriya, Kathie, Harari, Oscar, Buckland, Michael, Holtzman, David M., Rosenthal, Arnon, Schwabe, Tina, Tassi, Ilaria, Piccio, Laura
Publicado 2020