A genetically-informed study disentangling the relationships between tobacco smoking, cannabis use, alcohol consumption, substance use disorders and respiratory infections, includi...

por Rosoff, Daniel B., Yoo, Joyce, Lohoff, Falk W.
Publicado 2021

Smoking is significantly associated with increased risk of COVID-19 and other respiratory infections

por Rosoff, Daniel B., Yoo, Joyce, Lohoff, Falk W.
Publicado 2021

Prescription Opioid Use and Risk for Major Depressive Disorder and Anxiety and Stress-Related Disorders: A Multivariable Mendelian Randomization Analysis

por Rosoff, Daniel B., Smith, George Davey, Lohoff, Falk W.
Publicado 2020

Evaluating the relationship between alcohol consumption, tobacco use, and cardiovascular disease: A multivariable Mendelian randomization study

por Rosoff, Daniel B., Davey Smith, George, Mehta, Nehal, Clarke, Toni-Kim, Lohoff, Falk W.
Publicado 2020

Multi-omic underpinnings of epigenetic aging and human longevity

por Mavromatis, Lucas A., Rosoff, Daniel B., Bell, Andrew S., Jung, Jeesun, Wagner, Josephin, Lohoff, Falk W.
Publicado 2023

Comparing the Relationships of Genetically Proxied PCSK9 Inhibition With Mood Disorders, Cognition, and Dementia Between Men and Women: A Drug‐Target Mendelian Randomization Study...

por Bell, Andrew S., Rosoff, Daniel B., Mavromatis, Lucas A., Jung, Jeesun, Wagner, Josephin, Lohoff, Falk W.
Publicado 2022

Educational attainment reduces the risk of suicide attempt among individuals with and without psychiatric disorders independent of cognition: a bidirectional and multivariable Mend...

por Rosoff, Daniel B., Kaminsky, Zachary A., McIntosh, Andrew M., Davey Smith, George, Lohoff, Falk W.
Publicado 2020

Association Between Brain Structure and Alcohol Use Behaviors in Adults: A Mendelian Randomization and Multiomics Study

por Mavromatis, Lucas A., Rosoff, Daniel B., Cupertino, Renata B., Garavan, Hugh, Mackey, Scott, Lohoff, Falk W.
Publicado 2022

Assessing the Impact of PCSK9 and HMGCR Inhibition on Liver Function: Drug-Target Mendelian Randomization Analyses in Four Ancestries

por Rosoff, Daniel B., Bell, Andrew S., Wagner, Josephin, Mavromatis, Lucas A., Hamandi, Ali, Park, Lauren, Jung, Jeesun, Lohoff, Falk W.
Publicado 2023

Association of High-Intensity Binge Drinking With Lipid and Liver Function Enzyme Levels

por Rosoff, Daniel B., Charlet, Katrin, Jung, Jeesun, Lee, Jisoo, Muench, Christine, Luo, Audrey, Longley, Martha, Mauro, Kelsey L., Lohoff, Falk W.
Publicado 2019

Educational attainment impacts drinking behaviors and risk for alcohol dependence: results from a two-sample Mendelian randomization study with ~780,000 participants

por Rosoff, Daniel B., Clarke, Toni-Kim, Adams, Mark J., McIntosh, Andrew M., Davey Smith, George, Jung, Jeesun, Lohoff, Falk W.
Publicado 2019

Multivariate genome-wide analysis of aging-related traits identifies novel loci and new drug targets for healthy aging

por Rosoff, Daniel B., Mavromatis, Lucas A., Bell, Andrew S., Wagner, Josephin, Jung, Jeesun, Marioni, Riccardo E., Davey Smith, George, Horvath, Steve, Lohoff, Falk W.
Publicado 2023

Epigenetic aging is accelerated in alcohol use disorder and regulated by genetic variation in APOL2

por Luo, Audrey, Jung, Jeesun, Longley, Martha, Rosoff, Daniel B., Charlet, Katrin, Muench, Christine, Lee, Jisoo, Hodgkinson, Colin A., Goldman, David, Horvath, Steve, Kaminsky, Zachary A., Lohoff, Falk W.
Publicado 2019

Alcohol use disorder is associated with DNA methylation-based shortening of telomere length and regulated by TESPA1: implications for aging

por Jung, Jeesun, McCartney, Daniel L., Wagner, Josephin, Rosoff, Daniel B., Schwandt, Melanie, Sun, Hui, Wiers, Corinde E., de Carvalho, Luana Martins, Volkow, Nora D., Walker, Rosie M., Campbell, Archie, Porteous, David J., McIntosh, Andrew M., Marioni, Riccardo E., Horvath, Steve, Evans, Kathryn L., Lohoff, Falk W.
Publicado 2022

Epigenome-wide association study and multi-tissue replication of individuals with alcohol use disorder: evidence for abnormal glucocorticoid signaling pathway gene regulation

por Lohoff, Falk W., Roy, Arunima, Jung, Jeesun, Longley, Martha, Rosoff, Daniel B., Luo, Audrey, O’Connell, Emma, Sorcher, Jill L., Sun, Hui, Schwandt, Melanie, Hodgkinson, Colin A., Goldman, David, Momenan, Reza, McIntosh, Andrew M., Adams, Mark J., Walker, Rosie M., Evans, Kathryn L., Porteous, David, Smith, Alicia K., Lee, Jisoo, Muench, Christine, Charlet, Katrin, Clarke, Toni-Kim, Kaminsky, Zachary A.
Publicado 2020