Modeling complex neuropsychiatric disease with induced pluripotent stem cells

por Ross, P Joel, Ellis, James
Publicado 2010

Optimizing neuronal differentiation from induced pluripotent stem cells to model ASD

por Kim, Dae-Sung, Ross, P. Joel, Zaslavsky, Kirill, Ellis, James
Publicado 2014

Targeting NMDA receptors in neuropsychiatric disorders by drug screening on human neurons derived from pluripotent stem cells

por Zhang, Wenbo, Ross, P. Joel, Ellis, James, Salter, Michael W.
Publicado 2022

Modeling neuronal consequences of autism-associated gene regulatory variants with human induced pluripotent stem cells

por Ross, P. Joel, Mok, Rebecca S. F., Smith, Brandon S., Rodrigues, Deivid C., Mufteev, Marat, Scherer, Stephen W., Ellis, James
Publicado 2020

Fyn Kinase regulates GluN2B subunit-dominant NMDA receptors in human induced pluripotent stem cell-derived neurons

por Zhang, Wen-Bo, Ross, P. Joel, Tu, YuShan, Wang, Yongqian, Beggs, Simon, Sengar, Ameet S., Ellis, James, Salter, Michael W.
Publicado 2016

Human induced pluripotent stem cell derived neurons as a model for Williams-Beuren syndrome

por Khattak, Shahryar, Brimble, Elise, Zhang, Wenbo, Zaslavsky, Kirill, Strong, Emma, Ross, P. Joel, Hendry, Jason, Mital, Seema, Salter, Michael W., Osborne, Lucy R., Ellis, James
Publicado 2015

MECP2e1 isoform mutation affects the form and function of neurons derived from Rett syndrome patient iPS cells

por Djuric, Ugljesa, Cheung, Aaron Y. L., Zhang, Wenbo, Mok, Rebecca S., Lai, Wesley, Piekna, Alina, Hendry, Jason A., Ross, P. Joel, Pasceri, Peter, Kim, Dae-Sung, Salter, Michael W., Ellis, James
Publicado 2015

Disruption of DDX53 coding sequence has limited impact on iPSC-derived human NGN2 neurons

por Faheem, Muhammad, Deneault, Eric, Alexandrova, Roumiana, Rodrigues, Deivid C., Pellecchia, Giovanna, Shum, Carole, Zarrei, Mehdi, Piekna, Alina, Wei, Wei, Howe, Jennifer L., Thiruvahindrapuram, Bhooma, Lamoureux, Sylvia, Ross, P. Joel, Bradley, Clarrisa A., Ellis, James, Scherer, Stephen W.
Publicado 2023

SHANK2 mutations associated with Autism Spectrum Disorder cause hyperconnectivity of human neurons

por Zaslavsky, Kirill, Zhang, Wen-Bo, McCready, Fraser P., Rodrigues, Deivid C., Deneault, Eric, Loo, Caitlin, Zhao, Melody, Ross, P. Joel, Hajjar, Joelle El, Romm, Asli, Thompson, Tadeo, Piekna, Alina, Wei, Wei, Wang, Zhuozhi, Khattak, Shahryar, Mufteev, Marat, Pasceri, Peter, Scherer, Stephen W., Salter, Michael W., Ellis, James
Publicado 2019

Complete Disruption of Autism-Susceptibility Genes by Gene Editing Predominantly Reduces Functional Connectivity of Isogenic Human Neurons

por Deneault, Eric, White, Sean H., Rodrigues, Deivid C., Ross, P. Joel, Faheem, Muhammad, Zaslavsky, Kirill, Wang, Zhuozhi, Alexandrova, Roumiana, Pellecchia, Giovanna, Wei, Wei, Piekna, Alina, Kaur, Gaganjot, Howe, Jennifer L., Kwan, Vickie, Thiruvahindrapuram, Bhooma, Walker, Susan, Lionel, Anath C., Pasceri, Peter, Merico, Daniele, Yuen, Ryan K.C., Singh, Karun K., Ellis, James, Scherer, Stephen W.
Publicado 2018

Complete Disruption of Autism-Susceptibility Genes by Gene Editing Predominantly Reduces Functional Connectivity of Isogenic Human Neurons

por Deneault, Eric, White, Sean H., Rodrigues, Deivid C., Ross, P. Joel, Faheem, Muhammad, Zaslavsky, Kirill, Wang, Zhuozhi, Alexandrova, Roumiana, Pellecchia, Giovanna, Wei, Wei, Piekna, Alina, Kaur, Gaganjot, Howe, Jennifer L., Kwan, Vickie, Thiruvahindrapuram, Bhooma, Walker, Susan, Lionel, Anath C., Pasceri, Peter, Merico, Daniele, Yuen, Ryan K.C., Singh, Karun K., Ellis, James, Scherer, Stephen W.
Publicado 2019