A Rapid and Simple Method for DNA Engineering Using Cycled Ligation Assembly

di Roth, Theodore L., Milenkovic, Ljiljana, Scott, Matthew P.
Pubblicazione 2014

Type I Interferon Programs Innate Myeloid Dynamics and Gene Expression in the Virally Infected Nervous System

di Nayak, Debasis, Johnson, Kory R., Heydari, Sara, Roth, Theodore L., Zinselmeyer, Bernd H., McGavern, Dorian B.
Pubblicazione 2013

TRANSCRANIAL AMELIORATION OF INFLAMMATION AND CELL DEATH FOLLOWING BRAIN INJURY

di Roth, Theodore L., Nayak, Debasis, Atanasijevic, Tatjana, Koretsky, Alan P., Latour, Lawrence L., McGavern, Dorian B.
Pubblicazione 2013

Light-activated cell identification and sorting (LACIS) for selection of edited clones on a nanofluidic device

di Mocciaro, Annamaria, Roth, Theodore L., Bennett, Hayley M., Soumillon, Magali, Shah, Abhik, Hiatt, Joseph, Chapman, Kevin, Marson, Alexander, Lavieu, Gregory
Pubblicazione 2018

Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms

di Farboud, Behnom, Jarvis, Erin, Roth, Theodore L., Shin, Jiyung, Corn, Jacob E., Marson, Alexander, Meyer, Barbara J., Patel, Nipam H., Hochstrasser, Megan L.
Pubblicazione 2018

Migratory and adhesive cues controlling innate-like lymphocyte surveillance of the pathogen-exposed surface of the lymph node

di Zhang, Yang, Roth, Theodore L, Gray, Elizabeth E, Chen, Hsin, Rodda, Lauren B, Liang, Yin, Ventura, Patrick, Villeda, Saul, Crocker, Paul R, Cyster, Jason G
Pubblicazione 2016

Robust T cell activation requires an eIF3-driven burst in T cell receptor translation

di De Silva, Dasmanthie, Ferguson, Lucas, Chin, Grant H, Smith, Benjamin E, Apathy, Ryan A, Roth, Theodore L, Blaeschke, Franziska, Kudla, Marek, Marson, Alexander, Ingolia, Nicholas T, Cate, Jamie HD
Pubblicazione 2021

Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency

di Nguyen, David N., Roth, Theodore L., Li, P. Jonathan, Chen, Peixin Amy, Apathy, Ryan, Mamedov, Murad R., Vo, Linda T., Tobin, Victoria R., Goodman, Daniel, Shifrut, Eric, Bluestone, Jeffrey A., Puck, Jennifer M., Szoka, Francis C., Marson, Alexander
Pubblicazione 2019

The CD28-Transmembrane Domain Mediates Chimeric Antigen Receptor Heterodimerization With CD28

di Muller, Yannick D., Nguyen, Duy P., Ferreira, Leonardo M. R., Ho, Patrick, Raffin, Caroline, Valencia, Roxxana Valeria Beltran, Congrave-Wilson, Zion, Roth, Theodore L., Eyquem, Justin, Van Gool, Frederic, Marson, Alexander, Perez, Laurent, Wells, James A., Bluestone, Jeffrey A., Tang, Qizhi
Pubblicazione 2021

Epithelial miR-141 regulates IL-13–induced airway mucus production

di Siddiqui, Sana, Johansson, Kristina, Joo, Alex, Bonser, Luke R., Koh, Kyung Duk, Le Tonqueze, Olivier, Bolourchi, Samaneh, Bautista, Rodriel A., Zlock, Lorna, Roth, Theodore L., Marson, Alexander, Bhakta, Nirav R., Ansel, K. Mark, Finkbeiner, Walter E., Erle, David J., Woodruff, Prescott G.
Pubblicazione 2021

A large CRISPR-induced bystander mutation causes immune dysregulation

di Simeonov, Dimitre R., Brandt, Alexander J., Chan, Alice Y., Cortez, Jessica T., Li, Zhongmei, Woo, Jonathan M., Lee, Youjin, Carvalho, Claudia M. B., Indart, Alyssa C., Roth, Theodore L., Zou, James, May, Andrew P., Lupski, James R., Anderson, Mark S., Buaas, F. William, Rokhsar, Daniel S., Marson, Alexander
Pubblicazione 2019

XYZeq: Spatially resolved single-cell RNA sequencing reveals expression heterogeneity in the tumor microenvironment

di Lee, Youjin, Bogdanoff, Derek, Wang, Yutong, Hartoularos, George C., Woo, Jonathan M., Mowery, Cody T., Nisonoff, Hunter M., Lee, David S., Sun, Yang, Lee, James, Mehdizadeh, Sadaf, Cantlon, Joshua, Shifrut, Eric, Ngyuen, David N., Roth, Theodore L., Song, Yun S., Marson, Alexander, Chow, Eric D., Ye, Chun Jimmie
Pubblicazione 2021

Functional CRISPR dissection of gene networks controlling human regulatory T cell identity

di Schumann, Kathrin, Raju, Siddharth S., Lauber, Michael, Kolb, Saskia, Shifrut, Eric, Cortez, Jessica T., Skartsis, Nikolaos, Nguyen, Vinh Q., Woo, Jonathan M., Roth, Theodore L., Yu, Ruby, Nguyen, Michelle L. T., Simeonov, Dimitre R., Nguyen, David N., Targ, Sasha, Gate, Rachel E., Tang, Qizhi, Bluestone, Jeffrey A., Spitzer, Matthew H., Ye, Chun Jimmie, Marson, Alexander
Pubblicazione 2020

CRISPR Screen in Regulatory T Cells Reveals Modulators of Foxp3

di Cortez, Jessica T., Montauti, Elena, Shifrut, Eric, Gatchalian, Jovylyn, Zhang, Yusi, Shaked, Oren, Xu, Yuanming, Roth, Theodore L., Simeonov, Dimitre R., Zhang, Yana, Chen, Siqi, Li, Zhongmei, Woo, Jonathan M., Ho, Josephine, Vogel, Ian A., Prator, Grace Y., Zhang, Bin, Lee, Youjin, Sun, Zhaolin, Ifergan, Igal, Van Gool, Frédéric, Hargreaves, Diana C., Bluestone, Jeffrey A., Marson, Alexander, Fang, Deyu
Pubblicazione 2020

A functional map of HIV-host interactions in primary human T cells

di Hiatt, Joseph, Hultquist, Judd F., McGregor, Michael J., Bouhaddou, Mehdi, Leenay, Ryan T., Simons, Lacy M., Young, Janet M., Haas, Paige, Roth, Theodore L., Tobin, Victoria, Wojcechowskyj, Jason A., Woo, Jonathan M., Rathore, Ujjwal, Cavero, Devin A., Shifrut, Eric, Nguyen, Thong T., Haas, Kelsey M., Malik, Harmit S., Doudna, Jennifer A., May, Andrew P., Marson, Alexander, Krogan, Nevan J.
Pubblicazione 2022

Efficient generation of isogenic primary human myeloid cells using CRISPR-Cas9 ribonucleoproteins

di Hiatt, Joseph, Cavero, Devin A., McGregor, Michael J., Zheng, Weihao, Budzik, Jonathan M., Roth, Theodore L., Haas, Kelsey M., Wu, David, Rathore, Ujjwal, Meyer-Franke, Anke, Bouzidi, Mohamed S., Shifrut, Eric, Lee, Youjin, Kumar, Vigneshwari Easwar, Dang, Eric V., Gordon, David E., Wojcechowskyj, Jason A., Hultquist, Judd F., Fontaine, Krystal A., Pillai, Satish K., Cox, Jeffery S., Ernst, Joel D., Krogan, Nevan J., Marson, Alexander
Pubblicazione 2021

TCF-1 regulates HIV-specific CD8(+) T cell expansion capacity

di Rutishauser, Rachel L., Deguit, Christian Deo T., Hiatt, Joseph, Blaeschke, Franziska, Roth, Theodore L., Wang, Lynn, Raymond, Kyle A., Starke, Carly E., Mudd, Joseph C., Chen, Wenxuan, Smullin, Carolyn, Matus-Nicodemos, Rodrigo, Hoh, Rebecca, Krone, Melissa, Hecht, Frederick M., Pilcher, Christopher D., Martin, Jeffrey N., Koup, Richard A., Douek, Daniel C., Brenchley, Jason M., Sékaly, Rafick-Pierre, Pillai, Satish K., Marson, Alexander, Deeks, Steven G., McCune, Joseph M., Hunt, Peter W.
Pubblicazione 2021

RASA2 ablation in T cells boosts antigen sensitivity and long-term function

di Carnevale, Julia, Shifrut, Eric, Kale, Nupura, Nyberg, William A., Blaeschke, Franziska, Chen, Yan Yi, Li, Zhongmei, Bapat, Sagar P., Diolaiti, Morgan E., O’Leary, Patrick, Vedova, Shane, Belk, Julia, Daniel, Bence, Roth, Theodore L., Bachl, Stefanie, Anido, Alejandro Allo, Prinzing, Brooke, Ibañez-Vega, Jorge, Lange, Shannon, Haydar, Dalia, Luetke-Eversloh, Marie, Born-Bony, Maelys, Hegde, Bindu, Kogan, Scott, Feuchtinger, Tobias, Okada, Hideho, Satpathy, Ansuman T., Shannon, Kevin, Gottschalk, Stephen, Eyquem, Justin, Krenciute, Giedre, Ashworth, Alan, Marson, Alexander
Pubblicazione 2022

Reprogramming human T cell function and specificity with non-viral genome targeting

di Roth, Theodore L., Puig-Saus, Cristina, Yu, Ruby, Shifrut, Eric, Carnevale, Julia, Li, P. Jonathan, Hiatt, Joseph, Saco, Justin, Krystofinski, Paige, Li, Han, Tobin, Victoria, Nguyen, David N., Lee, Michael R., Putnam, Amy L., Ferris, Andrea L., Chen, Jeff W., Schickel, Jean-Nicolas, Pellerin, Laurence, Carmody, David, Alkorta-Aranburu, Gorka, Gaudio, Daniela Del, Matsumoto, Hiroyuki, Morell, Montse, Mao, Ying, Cho, Min, Quadros, Rolen M., Gurumurthy, Channabasavaiah B., Smith, Baz, Haugwitz, Michael, Hughes, Stephen H., Weissman, Jonathan S., Schumann, Kathrin, Esensten, Jonathan H., May, Andrew P., Ashworth, Alan, Kupfer, Gary M., Greeley, Siri Atma W., Bacchetta, Rosa, Meffre, Eric, Roncarolo, Maria Grazia, Romberg, Neil, Herold, Kevan C., Ribas, Antoni, Leonetti, Manuel D., Marson, Alexander
Pubblicazione 2018

A SARS-CoV-2 Protein Interaction Map Reveals Targets for Drug-Repurposing

di Gordon, David E., Jang, Gwendolyn M., Bouhaddou, Mehdi, Xu, Jiewei, Obernier, Kirsten, White, Kris M., O’Meara, Matthew J., Rezelj, Veronica V., Guo, Jeffrey Z., Swaney, Danielle L., Tummino, Tia A., Huettenhain, Ruth, Kaake, Robyn M., Richards, Alicia L., Tutuncuoglu, Beril, Foussard, Helene, Batra, Jyoti, Haas, Kelsey, Modak, Maya, Kim, Minkyu, Haas, Paige, Polacco, Benjamin J., Braberg, Hannes, Fabius, Jacqueline M., Eckhardt, Manon, Soucheray, Margaret, Bennett, Melanie J., Cakir, Merve, McGregor, Michael J., Li, Qiongyu, Meyer, Bjoern, Roesch, Ferdinand, Vallet, Thomas, Kain, Alice Mac, Miorin, Lisa, Moreno, Elena, Naing, Zun Zar Chi, Zhou, Yuan, Peng, Shiming, Shi, Ying, Zhang, Ziyang, Shen, Wenqi, Kirby, Ilsa T., Melnyk, James E., Chorba, John S., Lou, Kevin, Dai, Shizhong A., Barrio-Hernandez, Inigo, Memon, Danish, Hernandez-Armenta, Claudia, Lyu, Jiankun, Mathy, Christopher J.P., Perica, Tina, Pilla, Kala B., Ganesan, Sai J., Saltzberg, Daniel J., Rakesh, Ramachandran, Liu, Xi, Rosenthal, Sara B., Calviello, Lorenzo, Venkataramanan, Srivats, Liboy-Lugo, Jose, Lin, Yizhu, Huang, Xi-Ping, Liu, YongFeng, Wankowicz, Stephanie A., Bohn, Markus, Safari, Maliheh, Ugur, Fatima S., Koh, Cassandra, Savar, Nastaran Sadat, Tran, Quang Dinh, Shengjuler, Djoshkun, Fletcher, Sabrina J, O’Neal, Michael C., Cai, Yiming, C.J.Chang, Jason, Broadhurst, David J., Klippsten, Saker, Sharp, Phillip P., Wenzell, Nicole A., Kuzuoglu, Duygu, Wang, Hao-Yuan, Trenker, Raphael, Young, Janet M., Cavero, Devin A., Hiatt, Joseph, Roth, Theodore L., Rathore, Ujjwal, Subramanian, Advait, Noack, Julia, Hubert, Mathieu, Stroud, Robert M., Frankel, Alan D., Rosenberg, Oren S., Verba, Kliment A, Agard, David A., Ott, Melanie, Emerman, Michael, Jura, Natalia, von Zastrow, Mark, Verdin, Eric, Ashworth, Alan, Schwartz, Olivier, d’Enfert, Christophe, Mukherjee, Shaeri, Jacobson, Matt, Malik, Harmit S., Fujimori, Danica G., Ideker, Trey, Craik, Charles S., Floor, Stephen N., Fraser, James S., Gross, John D., Sali, Andrej, Roth, Bryan L., Ruggero, Davide, Taunton, Jack, Kortemme, Tanja, Beltrao, Pedro, Vignuzzi, Marco, García-Sastre, Adolfo, Shokat, Kevan M., Shoichet, Brian K., Krogan, Nevan J.
Pubblicazione 2020