A tribute to Marc Caron (1946–2022)

por Roth, Bryan
Publicado 2022

Contributions of molecular biology to antipsychotic drug discovery: promises fulfilled or unfulfilled?

por Roth, Bryan L.
Publicado 2006

DREADD: A Chemogenetic GPCR Signaling Platform

por Zhu, Hu, Roth, Bryan L.
Publicado 2014

Engineered G-protein Coupled Receptors are Powerful Tools to Investigate Biological Processes and Behaviors

por Nichols, Charles D., Roth, Bryan L.
Publicado 2009

Molecular insights into the regulation of constitutive activity by RNA editing of 5HT(2C) serotonin receptors

por Gumpper, Ryan H., Fay, Jonathan F., Roth, Bryan L.
Publicado 2022

A Pharmacological Organization of G Protein-coupled Receptors

por Lin, Henry, Sassano, Maria F., Roth, Bryan L., Shoichet, Brian K.
Publicado 2013

The G protein biased serotonin 5-HT 2A receptor agonist lisuride exerts anti-depressant drug-like activities in mice

por Pogorelov, Vladimir M., Rodriguiz, Ramona M., Roth, Bryan L., Wetsel, William C.
Publicado 2023

The G protein biased serotonin 5-HT2A receptor agonist lisuride exerts anti-depressant drug-like activities in mice

por Pogorelov, Vladimir M., Rodriguiz, Ramona M., Roth, Bryan L., Wetsel, William C.
Publicado 2023

Pharmacogenetic Modulation of Orexin Neurons Alters Sleep/Wakefulness States in Mice

por Sasaki, Koh, Suzuki, Mika, Mieda, Michihiro, Tsujino, Natsuko, Roth, Bryan, Sakurai, Takeshi
Publicado 2011

Colloidal Aggregation Causes Inhibition of G Protein-Coupled Receptors

por Sassano, Maria F., Doak, Allison K., Roth, Bryan L., Shoichet, Brian K.
Publicado 2013

Application of Quantitative Structure–Activity Relationship Models of 5-HT(1A) Receptor Binding to Virtual Screening Identifies Novel and Potent 5-HT(1A) Ligands

por Luo, Man, Wang, Xiang Simon, Roth, Bryan L., Golbraikh, Alexander, Tropsha, Alexander
Publicado 2014

Agonist and antagonist TRUPATH assays for G protein-coupled receptors

por DiBerto, Jeffrey F., Smart, Katie, Olsen, Reid H.J., Roth, Bryan L.
Publicado 2022

STRUCTURE OF THE D(2) DOPAMINE RECEPTOR BOUND TO THE ATYPICAL ANTIPSYCHOTIC DRUG RISPERIDONE

por Wang, Sheng, Che, Tao, Levit, Anat, Shoichet, Brian K., Wacker, Daniel, Roth, Bryan L.
Publicado 2018

The Ketamine Analogue Methoxetamine and 3- and 4-Methoxy Analogues of Phencyclidine Are High Affinity and Selective Ligands for the Glutamate NMDA Receptor

por Roth, Bryan L., Gibbons, Simon, Arunotayanun, Warunya, Huang, Xi-Ping, Setola, Vincent, Treble, Ric, Iversen, Les
Publicado 2013

The First Structure–Activity Relationship Studies for Designer Receptors Exclusively Activated by Designer Drugs

por Chen, Xin, Choo, Hyunah, Huang, Xi-Ping, Yang, Xiaobao, Stone, Orrin, Roth, Bryan L., Jin, Jian
Publicado 2015

Correction: The Ketamine Analogue Methoxetamine and 3- and 4-Methoxy Analogues of Phencyclidine Are High Affinity and Selective Ligands for the Glutamate NMDA Receptor

por Roth, Bryan L., Gibbons, Simon, Arunotayanun, Warunya, Huang, Xi-Ping, Setola, Vincent, Treble, Ric, Iversen, Les
Publicado 2018

trans-2-(2,5-Dimethoxy-4-iodophenyl)cyclopropylamine and trans-2-(2,5-dimethoxy-4-bromophenyl)cyclopropylamine as potent agonists for the 5-HT(2) receptor family

por Pigott, Adam, Frescas, Stewart, McCorvy, John D, Huang, Xi-Ping, Roth, Bryan L, Nichols, David E
Publicado 2012

Selectivity Challenges in Docking Screens for GPCR Targets and Antitargets

por Weiss, Dahlia R., Karpiak, Joel, Huang, Xi-Ping, Sassano, Maria F., Lyu, Jiankun, Roth, Bryan L., Shoichet, Brian K.
Publicado 2018

Isoquinoline Alkaloids Isolated from Corydalis yanhusuo and Their Binding Affinities at the Dopamine D(1) Receptor

por Ma, Zhong-Ze, Xu, Wei, Jensen, Niels H., Roth, Bryan L., Liu-Chen, Lee-Yuan, Lee, David Y. W.
Publicado 2008

A Miniaturized Screen of a Schistosoma mansoni Serotonergic G Protein-Coupled Receptor Identifies Novel Classes of Parasite-Selective Inhibitors

por Chan, John D., McCorvy, John D., Acharya, Sreemoyee, Johns, Malcolm E., Day, Timothy A., Roth, Bryan L., Marchant, Jonathan S.
Publicado 2016