Advances in targeted degradation of endogenous proteins

por Röth, Sascha, Fulcher, Luke J., Sapkota, Gopal P.
Publicado 2019

Proteolysis Targeting Chimeras (PROTACs): A Perspective on Integral Membrane Protein Degradation

por Ruffilli, Camilla, Roth, Sascha, Rodrigo, Monica, Boyd, Helen, Zelcer, Noam, Moreau, Kevin
Publicado 2022

Response to the letter to the editor ‘Novel imaging methods reveal positive impact of topical negative pressure application on tissue perfusion in an in‐vivo skin model’

por Müller‐Seubert, Wibke, Roth, Sascha, Hauck, Theresa, Arkudas, Andreas, Horch, Raymund E., Ludolph, Ingo
Publicado 2021

Novel imaging methods reveal positive impact of topical negative pressure application on tissue perfusion in an in vivo skin model

por Müller‐Seubert, Wibke, Roth, Sascha, Hauck, Theresa, Arkudas, Andreas, Horch, Raymund E., Ludolph, Ingo
Publicado 2021

Targeting Endogenous K-RAS for Degradation through the Affinity-Directed Protein Missile System

por Röth, Sascha, Macartney, Thomas J., Konopacka, Agnieszka, Chan, Kwok-Ho, Zhou, Houjiang, Queisser, Markus A., Sapkota, Gopal P.
Publicado 2020

Inducible Degradation of Target Proteins through a Tractable Affinity-Directed Protein Missile System

por Simpson, Luke M., Macartney, Thomas J., Nardin, Alice, Fulcher, Luke J., Röth, Sascha, Testa, Andrea, Maniaci, Chiara, Ciulli, Alessio, Ganley, Ian G., Sapkota, Gopal P.
Publicado 2020