A Rapid and Simple Method for DNA Engineering Using Cycled Ligation Assembly

por Roth, Theodore L., Milenkovic, Ljiljana, Scott, Matthew P.
Publicado 2014

Type I Interferon Programs Innate Myeloid Dynamics and Gene Expression in the Virally Infected Nervous System

por Nayak, Debasis, Johnson, Kory R., Heydari, Sara, Roth, Theodore L., Zinselmeyer, Bernd H., McGavern, Dorian B.
Publicado 2013

TRANSCRANIAL AMELIORATION OF INFLAMMATION AND CELL DEATH FOLLOWING BRAIN INJURY

por Roth, Theodore L., Nayak, Debasis, Atanasijevic, Tatjana, Koretsky, Alan P., Latour, Lawrence L., McGavern, Dorian B.
Publicado 2013

Light-activated cell identification and sorting (LACIS) for selection of edited clones on a nanofluidic device

por Mocciaro, Annamaria, Roth, Theodore L., Bennett, Hayley M., Soumillon, Magali, Shah, Abhik, Hiatt, Joseph, Chapman, Kevin, Marson, Alexander, Lavieu, Gregory
Publicado 2018

Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms

por Farboud, Behnom, Jarvis, Erin, Roth, Theodore L., Shin, Jiyung, Corn, Jacob E., Marson, Alexander, Meyer, Barbara J., Patel, Nipam H., Hochstrasser, Megan L.
Publicado 2018

Migratory and adhesive cues controlling innate-like lymphocyte surveillance of the pathogen-exposed surface of the lymph node

por Zhang, Yang, Roth, Theodore L, Gray, Elizabeth E, Chen, Hsin, Rodda, Lauren B, Liang, Yin, Ventura, Patrick, Villeda, Saul, Crocker, Paul R, Cyster, Jason G
Publicado 2016

Robust T cell activation requires an eIF3-driven burst in T cell receptor translation

por De Silva, Dasmanthie, Ferguson, Lucas, Chin, Grant H, Smith, Benjamin E, Apathy, Ryan A, Roth, Theodore L, Blaeschke, Franziska, Kudla, Marek, Marson, Alexander, Ingolia, Nicholas T, Cate, Jamie HD
Publicado 2021

Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency

por Nguyen, David N., Roth, Theodore L., Li, P. Jonathan, Chen, Peixin Amy, Apathy, Ryan, Mamedov, Murad R., Vo, Linda T., Tobin, Victoria R., Goodman, Daniel, Shifrut, Eric, Bluestone, Jeffrey A., Puck, Jennifer M., Szoka, Francis C., Marson, Alexander
Publicado 2019

The CD28-Transmembrane Domain Mediates Chimeric Antigen Receptor Heterodimerization With CD28

por Muller, Yannick D., Nguyen, Duy P., Ferreira, Leonardo M. R., Ho, Patrick, Raffin, Caroline, Valencia, Roxxana Valeria Beltran, Congrave-Wilson, Zion, Roth, Theodore L., Eyquem, Justin, Van Gool, Frederic, Marson, Alexander, Perez, Laurent, Wells, James A., Bluestone, Jeffrey A., Tang, Qizhi
Publicado 2021

Epithelial miR-141 regulates IL-13–induced airway mucus production

por Siddiqui, Sana, Johansson, Kristina, Joo, Alex, Bonser, Luke R., Koh, Kyung Duk, Le Tonqueze, Olivier, Bolourchi, Samaneh, Bautista, Rodriel A., Zlock, Lorna, Roth, Theodore L., Marson, Alexander, Bhakta, Nirav R., Ansel, K. Mark, Finkbeiner, Walter E., Erle, David J., Woodruff, Prescott G.
Publicado 2021

A large CRISPR-induced bystander mutation causes immune dysregulation

por Simeonov, Dimitre R., Brandt, Alexander J., Chan, Alice Y., Cortez, Jessica T., Li, Zhongmei, Woo, Jonathan M., Lee, Youjin, Carvalho, Claudia M. B., Indart, Alyssa C., Roth, Theodore L., Zou, James, May, Andrew P., Lupski, James R., Anderson, Mark S., Buaas, F. William, Rokhsar, Daniel S., Marson, Alexander
Publicado 2019

XYZeq: Spatially resolved single-cell RNA sequencing reveals expression heterogeneity in the tumor microenvironment

por Lee, Youjin, Bogdanoff, Derek, Wang, Yutong, Hartoularos, George C., Woo, Jonathan M., Mowery, Cody T., Nisonoff, Hunter M., Lee, David S., Sun, Yang, Lee, James, Mehdizadeh, Sadaf, Cantlon, Joshua, Shifrut, Eric, Ngyuen, David N., Roth, Theodore L., Song, Yun S., Marson, Alexander, Chow, Eric D., Ye, Chun Jimmie
Publicado 2021

Functional CRISPR dissection of gene networks controlling human regulatory T cell identity

por Schumann, Kathrin, Raju, Siddharth S., Lauber, Michael, Kolb, Saskia, Shifrut, Eric, Cortez, Jessica T., Skartsis, Nikolaos, Nguyen, Vinh Q., Woo, Jonathan M., Roth, Theodore L., Yu, Ruby, Nguyen, Michelle L. T., Simeonov, Dimitre R., Nguyen, David N., Targ, Sasha, Gate, Rachel E., Tang, Qizhi, Bluestone, Jeffrey A., Spitzer, Matthew H., Ye, Chun Jimmie, Marson, Alexander
Publicado 2020

CRISPR Screen in Regulatory T Cells Reveals Modulators of Foxp3

por Cortez, Jessica T., Montauti, Elena, Shifrut, Eric, Gatchalian, Jovylyn, Zhang, Yusi, Shaked, Oren, Xu, Yuanming, Roth, Theodore L., Simeonov, Dimitre R., Zhang, Yana, Chen, Siqi, Li, Zhongmei, Woo, Jonathan M., Ho, Josephine, Vogel, Ian A., Prator, Grace Y., Zhang, Bin, Lee, Youjin, Sun, Zhaolin, Ifergan, Igal, Van Gool, Frédéric, Hargreaves, Diana C., Bluestone, Jeffrey A., Marson, Alexander, Fang, Deyu
Publicado 2020

A functional map of HIV-host interactions in primary human T cells

por Hiatt, Joseph, Hultquist, Judd F., McGregor, Michael J., Bouhaddou, Mehdi, Leenay, Ryan T., Simons, Lacy M., Young, Janet M., Haas, Paige, Roth, Theodore L., Tobin, Victoria, Wojcechowskyj, Jason A., Woo, Jonathan M., Rathore, Ujjwal, Cavero, Devin A., Shifrut, Eric, Nguyen, Thong T., Haas, Kelsey M., Malik, Harmit S., Doudna, Jennifer A., May, Andrew P., Marson, Alexander, Krogan, Nevan J.
Publicado 2022

Efficient generation of isogenic primary human myeloid cells using CRISPR-Cas9 ribonucleoproteins

por Hiatt, Joseph, Cavero, Devin A., McGregor, Michael J., Zheng, Weihao, Budzik, Jonathan M., Roth, Theodore L., Haas, Kelsey M., Wu, David, Rathore, Ujjwal, Meyer-Franke, Anke, Bouzidi, Mohamed S., Shifrut, Eric, Lee, Youjin, Kumar, Vigneshwari Easwar, Dang, Eric V., Gordon, David E., Wojcechowskyj, Jason A., Hultquist, Judd F., Fontaine, Krystal A., Pillai, Satish K., Cox, Jeffery S., Ernst, Joel D., Krogan, Nevan J., Marson, Alexander
Publicado 2021

TCF-1 regulates HIV-specific CD8(+) T cell expansion capacity

por Rutishauser, Rachel L., Deguit, Christian Deo T., Hiatt, Joseph, Blaeschke, Franziska, Roth, Theodore L., Wang, Lynn, Raymond, Kyle A., Starke, Carly E., Mudd, Joseph C., Chen, Wenxuan, Smullin, Carolyn, Matus-Nicodemos, Rodrigo, Hoh, Rebecca, Krone, Melissa, Hecht, Frederick M., Pilcher, Christopher D., Martin, Jeffrey N., Koup, Richard A., Douek, Daniel C., Brenchley, Jason M., Sékaly, Rafick-Pierre, Pillai, Satish K., Marson, Alexander, Deeks, Steven G., McCune, Joseph M., Hunt, Peter W.
Publicado 2021

RASA2 ablation in T cells boosts antigen sensitivity and long-term function

por Carnevale, Julia, Shifrut, Eric, Kale, Nupura, Nyberg, William A., Blaeschke, Franziska, Chen, Yan Yi, Li, Zhongmei, Bapat, Sagar P., Diolaiti, Morgan E., O’Leary, Patrick, Vedova, Shane, Belk, Julia, Daniel, Bence, Roth, Theodore L., Bachl, Stefanie, Anido, Alejandro Allo, Prinzing, Brooke, Ibañez-Vega, Jorge, Lange, Shannon, Haydar, Dalia, Luetke-Eversloh, Marie, Born-Bony, Maelys, Hegde, Bindu, Kogan, Scott, Feuchtinger, Tobias, Okada, Hideho, Satpathy, Ansuman T., Shannon, Kevin, Gottschalk, Stephen, Eyquem, Justin, Krenciute, Giedre, Ashworth, Alan, Marson, Alexander
Publicado 2022

Reprogramming human T cell function and specificity with non-viral genome targeting

por Roth, Theodore L., Puig-Saus, Cristina, Yu, Ruby, Shifrut, Eric, Carnevale, Julia, Li, P. Jonathan, Hiatt, Joseph, Saco, Justin, Krystofinski, Paige, Li, Han, Tobin, Victoria, Nguyen, David N., Lee, Michael R., Putnam, Amy L., Ferris, Andrea L., Chen, Jeff W., Schickel, Jean-Nicolas, Pellerin, Laurence, Carmody, David, Alkorta-Aranburu, Gorka, Gaudio, Daniela Del, Matsumoto, Hiroyuki, Morell, Montse, Mao, Ying, Cho, Min, Quadros, Rolen M., Gurumurthy, Channabasavaiah B., Smith, Baz, Haugwitz, Michael, Hughes, Stephen H., Weissman, Jonathan S., Schumann, Kathrin, Esensten, Jonathan H., May, Andrew P., Ashworth, Alan, Kupfer, Gary M., Greeley, Siri Atma W., Bacchetta, Rosa, Meffre, Eric, Roncarolo, Maria Grazia, Romberg, Neil, Herold, Kevan C., Ribas, Antoni, Leonetti, Manuel D., Marson, Alexander
Publicado 2018

A SARS-CoV-2 Protein Interaction Map Reveals Targets for Drug-Repurposing

por Gordon, David E., Jang, Gwendolyn M., Bouhaddou, Mehdi, Xu, Jiewei, Obernier, Kirsten, White, Kris M., O’Meara, Matthew J., Rezelj, Veronica V., Guo, Jeffrey Z., Swaney, Danielle L., Tummino, Tia A., Huettenhain, Ruth, Kaake, Robyn M., Richards, Alicia L., Tutuncuoglu, Beril, Foussard, Helene, Batra, Jyoti, Haas, Kelsey, Modak, Maya, Kim, Minkyu, Haas, Paige, Polacco, Benjamin J., Braberg, Hannes, Fabius, Jacqueline M., Eckhardt, Manon, Soucheray, Margaret, Bennett, Melanie J., Cakir, Merve, McGregor, Michael J., Li, Qiongyu, Meyer, Bjoern, Roesch, Ferdinand, Vallet, Thomas, Kain, Alice Mac, Miorin, Lisa, Moreno, Elena, Naing, Zun Zar Chi, Zhou, Yuan, Peng, Shiming, Shi, Ying, Zhang, Ziyang, Shen, Wenqi, Kirby, Ilsa T., Melnyk, James E., Chorba, John S., Lou, Kevin, Dai, Shizhong A., Barrio-Hernandez, Inigo, Memon, Danish, Hernandez-Armenta, Claudia, Lyu, Jiankun, Mathy, Christopher J.P., Perica, Tina, Pilla, Kala B., Ganesan, Sai J., Saltzberg, Daniel J., Rakesh, Ramachandran, Liu, Xi, Rosenthal, Sara B., Calviello, Lorenzo, Venkataramanan, Srivats, Liboy-Lugo, Jose, Lin, Yizhu, Huang, Xi-Ping, Liu, YongFeng, Wankowicz, Stephanie A., Bohn, Markus, Safari, Maliheh, Ugur, Fatima S., Koh, Cassandra, Savar, Nastaran Sadat, Tran, Quang Dinh, Shengjuler, Djoshkun, Fletcher, Sabrina J, O’Neal, Michael C., Cai, Yiming, C.J.Chang, Jason, Broadhurst, David J., Klippsten, Saker, Sharp, Phillip P., Wenzell, Nicole A., Kuzuoglu, Duygu, Wang, Hao-Yuan, Trenker, Raphael, Young, Janet M., Cavero, Devin A., Hiatt, Joseph, Roth, Theodore L., Rathore, Ujjwal, Subramanian, Advait, Noack, Julia, Hubert, Mathieu, Stroud, Robert M., Frankel, Alan D., Rosenberg, Oren S., Verba, Kliment A, Agard, David A., Ott, Melanie, Emerman, Michael, Jura, Natalia, von Zastrow, Mark, Verdin, Eric, Ashworth, Alan, Schwartz, Olivier, d’Enfert, Christophe, Mukherjee, Shaeri, Jacobson, Matt, Malik, Harmit S., Fujimori, Danica G., Ideker, Trey, Craik, Charles S., Floor, Stephen N., Fraser, James S., Gross, John D., Sali, Andrej, Roth, Bryan L., Ruggero, Davide, Taunton, Jack, Kortemme, Tanja, Beltrao, Pedro, Vignuzzi, Marco, García-Sastre, Adolfo, Shokat, Kevan M., Shoichet, Brian K., Krogan, Nevan J.
Publicado 2020