The finger loop of the SRA domain in the E3 ligase UHRF1 is a regulator of ubiquitin targeting and is required for the maintenance of DNA methylation

por Vaughan, Robert M., Rothbart, Scott B., Dickson, Bradley M.
Publicado 2019

Analysis of histone antibody specificity directly in sequencing data using siQ-ChIP

por Kupai, Ariana, Vaughan, Robert M., Rothbart, Scott B., Dickson, Bradley M.
Publicado 2023

Streamlined quantitative analysis of histone modification abundance at nucleosome-scale resolution with siQ-ChIP version 2.0

por Dickson, Bradley M., Kupai, Ariana, Vaughan, Robert M., Rothbart, Scott B.
Publicado 2023

A Degenerate Peptide Library Approach to Reveal Sequence Determinants of Methyllysine-Driven Protein Interactions

por Kupai, Ariana, Vaughan, Robert M., Dickson, Bradley M., Rothbart, Scott B.
Publicado 2020

Mitotic chromatin marking governs asymmetric segregation of DNA damage

por Ferrand, Juliette, Dabin, Juliette, Chevallier, Odile, Kupai, Ariana, Rothbart, Scott B., Polo, Sophie E.
Publicado 2023

Comparative biochemical analysis of UHRF proteins reveals molecular mechanisms that uncouple UHRF2 from DNA methylation maintenance

por Vaughan, Robert M, Dickson, Bradley M, Cornett, Evan M, Harrison, Joseph S, Kuhlman, Brian, Rothbart, Scott B
Publicado 2018

Binding specificity and function of the SWI/SNF subunit SMARCA4 bromodomain interaction with acetylated histone H3K14

por Enríquez, Paul, Krajewski, Krzysztof, Strahl, Brian D., Rothbart, Scott B., Dowen, Robert H., Rose, Robert B.
Publicado 2021

A physical basis for quantitative ChIP-sequencing

por Dickson, Bradley M., Tiedemann, Rochelle L., Chomiak, Alison A., Cornett, Evan M., Vaughan, Robert M., Rothbart, Scott B.
Publicado 2020

Poly-acetylated chromatin signatures are preferred epitopes for site-specific histone H4 acetyl antibodies

por Rothbart, Scott B., Lin, Shu, Britton, Laura-Mae, Krajewski, Krzysztof, Keogh, Michael-C, Garcia, Benjamin A., Strahl, Brian D.
Publicado 2012

Study of mitotic chromatin supports a model of bookmarking by histone modifications and reveals nucleosome deposition patterns

por Javasky, Elisheva, Shamir, Inbal, Gandhi, Shashi, Egri, Shawn, Sandler, Oded, Rothbart, Scott B., Kaplan, Noam, Jaffe, Jacob D., Goren, Alon, Simon, Itamar
Publicado 2018

Histone peptide microarray screen of chromo and Tudor domains defines new histone lysine methylation interactions

por Shanle, Erin K., Shinsky, Stephen A., Bridgers, Joseph B., Bae, Narkhyun, Sagum, Cari, Krajewski, Krzysztof, Rothbart, Scott B., Bedford, Mark T., Strahl, Brian D.
Publicado 2017

Global lysine methylome profiling using systematically characterized affinity reagents

por Berryhill, Christine A., Hanquier, Jocelyne N., Doud, Emma H., Cordeiro-Spinetti, Eric, Dickson, Bradley M., Rothbart, Scott B., Mosley, Amber L., Cornett, Evan M.
Publicado 2023

Systematic comparison of monoclonal versus polyclonal antibodies for mapping histone modifications by ChIP-seq

por Busby, Michele, Xue, Catherine, Li, Catherine, Farjoun, Yossi, Gienger, Elizabeth, Yofe, Ido, Gladden, Adrianne, Epstein, Charles B., Cornett, Evan M., Rothbart, Scott B., Nusbaum, Chad, Goren, Alon
Publicado 2016

ARID1A-dependent maintenance of H3.3 is required for repressive CHD4-ZMYND8 chromatin interactions at super-enhancers

por Reske, Jake J., Wilson, Mike R., Armistead, Brooke, Harkins, Shannon, Perez, Cristina, Hrit, Joel, Adams, Marie, Rothbart, Scott B., Missmer, Stacey A., Fazleabas, Asgerally T., Chandler, Ronald L.
Publicado 2022

Structural basis for DNMT3A-mediated de novo DNA methylation

por Zhang, Zhi-Min, Lu, Rui, Wang, Pengcheng, Yu, Yang, Chen, Dong-Liang, Gao, Linfeng, Liu, Shuo, Ji, Debin, Rothbart, Scott B, Wang, Yinsheng, Wang, Gang Greg, Song, Jikui
Publicado 2018

Chromatin structure and its chemical modifications regulate the ubiquitin ligase substrate selectivity of UHRF1

por Vaughan, Robert M., Dickson, Bradley M., Whelihan, Matthew F., Johnstone, Andrea L., Cornett, Evan M., Cheek, Marcus A., Ausherman, Christine A., Cowles, Martis W., Sun, Zu-Wen, Rothbart, Scott B.
Publicado 2018

A Read/Write Mechanism Connects p300 Bromodomain Function to H2A.Z Acetylation

por Colino-Sanguino, Yolanda, Cornett, Evan M., Moulder, David, Smith, Grady C., Hrit, Joel, Cordeiro-Spinetti, Eric, Vaughan, Robert M., Krajewski, Krzysztof, Rothbart, Scott B., Clark, Susan J., Valdés-Mora, Fátima
Publicado 2019

Association of UHRF1 with H3K9 methylation directs the maintenance of DNA methylation

por Rothbart, Scott B., Krajewski, Krzysztof, Nady, Nataliya, Tempel, Wolfram, Xue, Sheng, Badeaux, Aimee I., Barsyte-Lovejoy, Dalia, Martinez, Jorge Y., Bedford, Mark T., Fuchs, Stephen M., Arrowsmith, Cheryl H., Strahl, Brian D.
Publicado 2012

A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex

por Ma, Honglei, Duan, Jingbo, Ke, Jiyuan, He, Yuanzheng, Gu, Xin, Xu, Ting-Hai, Yu, Hong, Wang, Yonghong, Brunzelle, Joseph S., Jiang, Yi, Rothbart, Scott B., Xu, H. Eric, Li, Jiayang, Melcher, Karsten
Publicado 2017

Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a

por Strikoudis, Alexandros, Lazaris, Charalampos, Trimarchi, Thomas, Neto, Antonio L. Galvao, Yang, Yan, Ntziachristos, Panagiotis, Rothbart, Scott, Buckley, Shannon, Dolgalev, Igor, Stadtfeld, Matthias, Strahl, Brian D., Dynlacht, Brian D., Tsirigos, Aristotelis, Aifantis, Iannis
Publicado 2016