Brief Guide: Experimental Strategies for High-Quality Hit Selection from Small-Molecule Screening Campaigns

por Rothenaigner, Ina, Hadian, Kamyar
Publicado 2021

CellDeathPred: a deep learning framework for ferroptosis and apoptosis prediction based on cell painting

por Schorpp, Kenji, Bessadok, Alaa, Biibosunov, Aidin, Rothenaigner, Ina, Strasser, Stefanie, Peng, Tingying, Hadian, Kamyar
Publicado 2023

ABCA3 Deficiency—Variant-Specific Response to Hydroxychloroquine

por Yang, Xiaohua, Forstner, Maria, Rapp, Christina K., Rothenaigner, Ina, Li, Yang, Hadian, Kamyar, Griese, Matthias
Publicado 2023

New Small Molecules Targeting Apoptosis and Cell Viability in Osteosarcoma

por Maugg, Doris, Rothenaigner, Ina, Schorpp, Kenji, Potukuchi, Harish Kumar, Korsching, Eberhard, Baumhoer, Daniel, Hadian, Kamyar, Smida, Jan, Nathrath, Michaela
Publicado 2015

Identification of Small-Molecule Frequent Hitters from AlphaScreen High-Throughput Screens

por Schorpp, Kenji, Rothenaigner, Ina, Salmina, Elena, Reinshagen, Jeanette, Low, Terence, Brenke, Jara K., Gopalakrishnan, Jay, Tetko, Igor V., Gul, Sheraz, Hadian, Kamyar
Publicado 2014

A 3D-microtissue-based phenotypic screening of radiation resistant tumor cells with synchronized chemotherapeutic treatment

por Anastasov, Nataša, Höfig, Ines, Radulović, Vanja, Ströbel, Simon, Salomon, Michael, Lichtenberg, Jan, Rothenaigner, Ina, Hadian, Kamyar, Kelm, Jens M., Thirion, Christian, Atkinson, Michael J.
Publicado 2015

Retinoic acid signaling is critical during the totipotency window in early mammalian development

por Iturbide, Ane, Ruiz Tejada Segura, Mayra L., Noll, Camille, Schorpp, Kenji, Rothenaigner, Ina, Ruiz-Morales, Elias R., Lubatti, Gabriele, Agami, Ahmed, Hadian, Kamyar, Scialdone, Antonio, Torres-Padilla, Maria-Elena
Publicado 2021

Author Correction: Retinoic acid signaling is critical during the totipotency window in early mammalian development

por Iturbide, Ane, Ruiz Tejada Segura, Mayra L., Noll, Camille, Schorpp, Kenji, Rothenaigner, Ina, Ruiz-Morales, Elias R., Lubatti, Gabriele, Agami, Ahmed, Hadian, Kamyar, Scialdone, Antonio, Torres-Padilla, Maria-Elena
Publicado 2022

A drug screen with approved compounds identifies amlexanox as a novel Wnt/β-catenin activator inducing lung epithelial organoid formation

por Costa, Rita, Wagner, Darcy E., Doryab, Ali, De Santis, Martina M., Schorpp, Kenji, Rothenaigner, Ina, Lehmann, Mareike, Baarsma, Hoeke A., Liu, Xueping, Schmid, Otmar, Campillos, Monica, Yildirim, Ali Önder, Hadian, Kamyar, Königshoff, Melanie
Publicado 2021

Farnesoid X receptor activation by bile acids suppresses lipid peroxidation and ferroptosis

por Tschuck, Juliane, Theilacker, Lea, Rothenaigner, Ina, Weiß, Stefanie A. I., Akdogan, Banu, Lam, Van Thanh, Müller, Constanze, Graf, Roman, Brandner, Stefanie, Pütz, Christian, Rieder, Tamara, Schmitt-Kopplin, Philippe, Vincendeau, Michelle, Zischka, Hans, Schorpp, Kenji, Hadian, Kamyar
Publicado 2023

Combination therapies induce cancer cell death through the integrated stress response and disturbed pyrimidine metabolism

por Hartleben, Goetz, Schorpp, Kenji, Kwon, Yun, Betz, Barbara, Tsokanos, Foivos‐Filippos, Dantes, Zahra, Schäfer, Arlett, Rothenaigner, Ina, Monroy Kuhn, José Manuel, Morigny, Pauline, Mehr, Lisa, Lin, Sean, Seitz, Susanne, Tokarz, Janina, Artati, Anna, Adamsky, Jerzy, Plettenburg, Oliver, Lutter, Dominik, Irmler, Martin, Beckers, Johannes, Reichert, Maximilian, Hadian, Kamyar, Zeigerer, Anja, Herzig, Stephan, Berriel Diaz, Mauricio
Publicado 2021

Acriflavine, a clinically approved drug, inhibits SARS-CoV-2 and other betacoronaviruses

por Napolitano, Valeria, Dabrowska, Agnieszka, Schorpp, Kenji, Mourão, André, Barreto-Duran, Emilia, Benedyk, Malgorzata, Botwina, Pawel, Brandner, Stefanie, Bostock, Mark, Chykunova, Yuliya, Czarna, Anna, Dubin, Grzegorz, Fröhlich, Tony, Hölscher, Michael, Jedrysik, Malwina, Matsuda, Alex, Owczarek, Katarzyna, Pachota, Magdalena, Plettenburg, Oliver, Potempa, Jan, Rothenaigner, Ina, Schlauderer, Florian, Slysz, Klaudia, Szczepanski, Artur, Greve-Isdahl Mohn, Kristin, Blomberg, Bjorn, Sattler, Michael, Hadian, Kamyar, Popowicz, Grzegorz Maria, Pyrc, Krzysztof
Publicado 2022