Circulating tumour DNA — looking beyond the blood

por Tivey, Ann, Church, Matt, Rothwell, Dominic, Dive, Caroline, Cook, Natalie
Publicado 2022

Early Dissemination of Circulating Tumor Cells: Biological and Clinical Insights

por Chemi, Francesca, Mohan, Sumitra, Guevara, Tatiana, Clipson, Alexandra, Rothwell, Dominic G., Dive, Caroline
Publicado 2021

Circulating Tumour DNA in Melanoma—Clinic Ready?

por Tivey, Ann, Britton, Fiona, Scott, Julie-Ann, Rothwell, Dominic, Lorigan, Paul, Lee, Rebecca
Publicado 2022

In silico error correction improves cfDNA mutation calling

por Kim, Chang Sik, Mohan, Sumitra, Ayub, Mahmood, Rothwell, Dominic G, Dive, Caroline, Brady, Ged, Miller, Crispin
Publicado 2019

Evidence of clinical efficacy of a first generation CD19 CAR T cell in B cell malignancies

por Shohdy, Kyrillus S., Pillai, Manon, Guest, Ryan, Rothwell, Dominic, Kirillova, Natalia, Chow, Shien, Gilham, David, Thistlethwaite, Fiona, Hawkins, Robert
Publicado 2023

First generation anti-CD19 chimeric antigen receptor-modified T cells for management of B cell malignances: initial analysis of an ongoing Phase I clinical trial

por Evans, Manon, Guest, Ryan, Rothwell, Dominic, Burt, Debbie, Kirillova, Natalia, Haughton, Jennifer, Chow, Shien, Thistlethwaite, Fiona, Gilham, David, Hawkins, Robert
Publicado 2014

Genetic profiling of tumours using both circulating free DNA and circulating tumour cells isolated from the same preserved whole blood sample

por Rothwell, Dominic G., Smith, Nigel, Morris, Daniel, Leong, Hui Sun, Li, Yaoyong, Hollebecque, Antoine, Ayub, Mahmood, Carter, Louise, Antonello, Jenny, Franklin, Lynsey, Miller, Crispin, Blackhall, Fiona, Dive, Caroline, Brady, Ged
Publicado 2015

Development of a circulating miRNA assay to monitor tumor burden: From mouse to man

por Greystoke, Alastair, Ayub, Mahmood, Rothwell, Dominic G., Morris, Dan, Burt, Deborah, Hodgkinson, Cassandra L., Morrow, Christopher J., Smith, Nigel, Aung, Kyaw, Valle, Juan, Carter, Louise, Blackhall, Fiona, Dive, Caroline, Brady, Ged
Publicado 2015

Evaluation and validation of a robust single cell RNA-amplification protocol through transcriptional profiling of enriched lung cancer initiating cells

por Rothwell, Dominic G, Li, Yaoyong, Ayub, Mahmood, Tate, Catriona, Newton, Gillian, Hey, Yvonne, Carter, Louise, Faulkner, Suzanne, Moro, Massimo, Pepper, Stuart, Miller, Crispin, Blackhall, Fiona, Bertolini, Giulia, Roz, Luca, Dive, Caroline, Brady, Ged
Publicado 2014

Molecular analysis of single circulating tumour cells following long‐term storage of clinical samples

por Mesquita, Barbara, Rothwell, Dominic G., Burt, Deborah J, Chemi, Francesca, Fernandez‐Gutierrez, Fabiola, Slane‐Tan, Daniel, Antonello, Jenny, Carter, Mathew, Carter, Louise, Parry, Marina, Franklin, Lynsey, Marais, Richard, Blackhall, Fiona, Dive, Caroline, Brady, Ged
Publicado 2017

Analysis of circulating cell-free DNA identifies KRAS copy number gain and mutation as a novel prognostic marker in Pancreatic cancer

por Mohan, Sumitra, Ayub, Mahmood, Rothwell, Dominic G., Gulati, Sakshi, Kilerci, Bedirhan, Hollebecque, Antoine, Sun Leong, Hui, Smith, Nigel K., Sahoo, Sudhakar, Descamps, Tine, Zhou, Cong, Hubner, Richard A., McNamara, Mairéad G., Lamarca, Angela, Valle, Juan W., Dive, Caroline, Brady, Ged
Publicado 2019

Profiling of Circulating Free DNA Using Targeted and Genome-wide Sequencing in Patients with SCLC

por Mohan, Sumitra, Foy, Victoria, Ayub, Mahmood, Leong, Hui Sun, Schofield, Pieta, Sahoo, Sudhakar, Descamps, Tine, Kilerci, Bedirhan, Smith, Nigel K., Carter, Mathew, Priest, Lynsey, Zhou, Cong, Carr, T. Hedley, Miller, Crispin, Faivre-Finn, Corinne, Blackhall, Fiona, Rothwell, Dominic G., Dive, Caroline, Brady, Gerard
Publicado 2020

The clinical efficacy of first-generation carcinoembryonic antigen (CEACAM5)-specific CAR T cells is limited by poor persistence and transient pre-conditioning-dependent respirator...

por Thistlethwaite, Fiona C., Gilham, David E., Guest, Ryan D., Rothwell, Dominic G., Pillai, Manon, Burt, Deborah J., Byatte, Andrea J., Kirillova, Natalia, Valle, Juan W., Sharma, Surinder K., Chester, Kerry A., Westwood, Nigel B., Halford, Sarah E. R., Nabarro, Stephen, Wan, Susan, Austin, Eric, Hawkins, Robert E.
Publicado 2017

Technical Evaluation of Commercial Mutation Analysis Platforms and Reference Materials for Liquid Biopsy Profiling

por Weber, Sabrina, Spiegl, Benjamin, Perakis, Samantha O., Ulz, Christine M., Abuja, Peter M., Kashofer, Karl, van der Leest, Paul, Azpurua, Maria Aguirre, Tamminga, Menno, Brudzewsky, Dan, Rothwell, Dominic G., Mohan, Sumitra, Sartori, Alexander, Lampignano, Rita, Konigshofer, Yves, Sprenger-Haussels, Markus, Wikman, Harriet, Bergheim, Inger R., Kloten, Vera, Schuuring, Ed, Speicher, Michael R., Heitzer, Ellen
Publicado 2020

cfDNA methylome profiling for detection and subtyping of small cell lung cancers

por Chemi, Francesca, Pearce, Simon P., Clipson, Alexandra, Hill, Steven M., Conway, Alicia-Marie, Richardson, Sophie A., Kamieniecka, Katarzyna, Caeser, Rebecca, White, Daniel J., Mohan, Sumitra, Foy, Victoria, Simpson, Kathryn L., Galvin, Melanie, Frese, Kristopher K., Priest, Lynsey, Egger, Jacklynn, Kerr, Alastair, Massion, Pierre P., Poirier, John T., Brady, Gerard, Blackhall, Fiona, Rothwell, Dominic G., Rudin, Charles M., Dive, Caroline
Publicado 2022

Vasculogenic mimicry in small cell lung cancer

por Williamson, Stuart C., Metcalf, Robert L., Trapani, Francesca, Mohan, Sumitra, Antonello, Jenny, Abbott, Benjamin, Leong, Hui Sun, Chester, Christopher P. E., Simms, Nicole, Polanski, Radoslaw, Nonaka, Daisuke, Priest, Lynsey, Fusi, Alberto, Carlsson, Fredrika, Carlsson, Anders, Hendrix, Mary J. C., Seftor, Richard E. B., Seftor, Elisabeth A., Rothwell, Dominic G., Hughes, Andrew, Hicks, James, Miller, Crispin, Kuhn, Peter, Brady, Ged, Simpson, Kathryn L., Blackhall, Fiona H., Dive, Caroline
Publicado 2016