Who wants to be a scientist ?: choosing science as a career

por Rothwell, Nancy
Publicado 2002

Pannexin-1-dependent caspase-1 activation and secretion of IL-1β is regulated by zinc

por Brough, David, Pelegrin, Pablo, Rothwell, Nancy J
Publicado 2009

The Dynamics and Mechanisms of Interleukin-1α and β Nuclear Import

por Luheshi, Nadia M, Rothwell, Nancy J, Brough, David
Publicado 2008

Release of Interleukin-1α or Interleukin-1β Depends on Mechanism of Cell Death

por England, Hazel, Summersgill, Holly R., Edye, Michelle E., Rothwell, Nancy J., Brough, David
Publicado 2014

Central and haematopoietic interleukin-1 both contribute to ischaemic brain injury in mice

por Denes, Adam, Wilkinson, Fiona, Bigger, Brian, Chu, Michael, Rothwell, Nancy J., Allan, Stuart M.
Publicado 2013

Long-term functional recovery and compensation after cerebral ischemia in rats

por Girard, Sylvie, Murray, Katie N., Rothwell, Nancy J., Metz, Gerlinde A.S., Allan, Stuart M.
Publicado 2014

Microglia and Macrophages Differentially Modulate Cell Death After Brain Injury Caused by Oxygen-Glucose Deprivation in Organotypic Brain Slices

por Girard, Sylvie, Brough, David, Lopez-Castejon, Gloria, Giles, James, Rothwell, Nancy J, Allan, Stuart M
Publicado 2013

Surgical manipulation compromises leukocyte mobilization responses and inflammation after experimental cerebral ischemia in mice

por Denes, Adam, Pradillo, Jesus M., Drake, Caroline, Buggey, Hannah, Rothwell, Nancy J., Allan, Stuart M.
Publicado 2014

Tumor Necrosis Factor α Is a Critical Component of Interleukin 13–Mediated Protective T Helper Cell Type 2 Responses during Helminth Infection

por Artis, David, Humphreys, Neil E., Bancroft, Allison J., Rothwell, Nancy J., Potten, Christopher S., Grencis, Richard K.
Publicado 1999

Interleukin-1 receptor antagonist is beneficial after subarachnoid haemorrhage in rat by blocking haem-driven inflammatory pathology

por Greenhalgh, Andrew D., Brough, David, Robinson, Emily M., Girard, Sylvie, Rothwell, Nancy J., Allan, Stuart M.
Publicado 2012

Neuronal toll-like receptor 4 signaling induces brain endothelial activation and neutrophil transmigration in vitro

por Leow-Dyke, Sophie, Allen, Charlotte, Denes, Adam, Nilsson, Olov, Maysami, Samaneh, Bowie, Andrew G, Rothwell, Nancy J, Pinteaux, Emmanuel
Publicado 2012

The role of cortisol in immunosuppression in subarachnoid haemorrhage

por Hoadley, Margaret E., Galea, James, Singh, Navneet, Hulme, Sharon, Ajao, David O., Rothwell, Nancy, King, Andrew, Tyrrell, Pippa, Hopkins, Stephen J.
Publicado 2023

Inflammation as a predictor for delayed cerebral ischemia after aneurysmal subarachnoid haemorrhage

por McMahon, Catherine J, Hopkins, Stephen, Vail, Andy, King, Andrew T, Smith, Debi, Illingworth, Karen J, Clark, Simon, Rothwell, Nancy J, Tyrrell, Pippa J
Publicado 2013

Interleukin-1 primes human mesenchymal stem cells towards an anti-inflammatory and pro-trophic phenotype in vitro

por Redondo-Castro, Elena, Cunningham, Catriona, Miller, Jonjo, Martuscelli, Licia, Aoulad-Ali, Sarah, Rothwell, Nancy J., Kielty, Cay M., Allan, Stuart M., Pinteaux, Emmanuel
Publicado 2017

Interleukin-1 Mediates Neuroinflammatory Changes Associated With Diet-Induced Atherosclerosis

por Denes, Adam, Drake, Caroline, Stordy, Jing, Chamberlain, Janet, McColl, Barry W., Gram, Hermann, Crossman, David, Francis, Sheila, Allan, Stuart M., Rothwell, Nancy J.
Publicado 2012

Intravenous anakinra can achieve experimentally effective concentrations in the central nervous system within a therapeutic time window: results of a dose-ranging study

por Galea, James, Ogungbenro, Kayode, Hulme, Sharon, Greenhalgh, Andrew, Aarons, Leon, Scarth, Sylvia, Hutchinson, Peter, Grainger, Samantha, King, Andrew, Hopkins, Stephen J, Rothwell, Nancy, Tyrrell, Pippa
Publicado 2011

Requirement for interleukin-1 to drive brain inflammation reveals tissue-specific mechanisms of innate immunity

por Giles, James A, Greenhalgh, Andrew D, Davies, Claire L, Denes, Adam, Shaw, Tovah, Coutts, Graham, Rothwell, Nancy J, McColl, Barry W, Allan, Stuart M
Publicado 2015

Efficient discovery of anti-inflammatory small molecule combinations using evolutionary computing

por Small, Ben G, McColl, Barry W, Allmendinger, Richard, Pahle, Jürgen, López-Castejón, Gloria, Rothwell, Nancy J, Knowles, Joshua, Mendes, Pedro, Brough, David, Kell, Douglas B
Publicado 2011

The effect of intravenous interleukin-1 receptor antagonist on inflammatory mediators in cerebrospinal fluid after subarachnoid haemorrhage: a phase II randomised controlled trial

por Singh, Navneet, Hopkins, Stephen J, Hulme, Sharon, Galea, James P, Hoadley, Margaret, Vail, Andy, Hutchinson, Peter J, Grainger, Samantha, Rothwell, Nancy J, King, Andrew T, Tyrrell, Pippa J
Publicado 2014

Reparative effects of interleukin-1 receptor antagonist in young and aged/co-morbid rodents after cerebral ischemia

por Pradillo, Jesus M., Murray, Katie N., Coutts, Graham A., Moraga, Ana, Oroz-Gonjar, Fernando, Boutin, Herve, Moro, Maria A., Lizasoain, Ignacio, Rothwell, Nancy J., Allan, Stuart M.
Publicado 2017