A Phase 3 Open-label, Randomized, Controlled Study to Evaluate the Efficacy and Safety of Intravenously Administered Ravulizumab Compared with Best Supportive Care in Patients with...

por Smith, Keisha, Pace, Amy, Ortiz, Stephan, Kazani, Shamsah, Rottinghaus, Scott
Publicado 2020

No evidence for hypogammaglobulinemia in patients with paroxysmal nocturnal hemoglobinuria (PNH) chronically treated with ravulizumab

por Alashkar, Ferras, Rottinghaus, Scott, Vance, Colin, Herich-Terhürne, Dörte, Dührsen, Ulrich, Assert, Roland, Röth, Alexander
Publicado 2020

One-year efficacy and safety of ravulizumab in adults with paroxysmal nocturnal hemoglobinuria naïve to complement inhibitor therapy: open-label extension of a randomized study

por Schrezenmeier, Hubert, Kulasekararaj, Austin, Mitchell, Lindsay, Sicre de Fontbrune, Flore, Devos, Timothy, Okamoto, Shinichiro, Wells, Richard, Rottinghaus, Scott T., Liu, Peng, Ortiz, Stephan, Lee, Jong Wook, Socié, Gérard
Publicado 2020

Assessing Preferences for Rare Disease Treatment: Qualitative Development of the Paroxysmal Nocturnal Hemoglobinuria Patient Preference Questionnaire (PNH-PPQ(©))

por Kaiser, Karen, Yount, Susan E, Martens, Christa E, Webster, Kimberly A, Shaunfield, Sara, Sparling, Amy, Peipert, John Devin, Cella, David, Rottinghaus, Scott T, Donato, Bonnie M K, Wells, Richard, Tomazos, Ioannis
Publicado 2020

Pharmacokinetic and pharmacodynamic effects of ravulizumab and eculizumab on complement component 5 in adults with paroxysmal nocturnal haemoglobinuria: results of two phase 3 rand...

por Peffault de Latour, Régis, Brodsky, Robert A., Ortiz, Stephan, Risitano, Antonio M., Jang, Jun H., Hillmen, Peter, Kulagin, Alexander D., Kulasekararaj, Austin G., Rottinghaus, Scott T., Aguzzi, Rasha, Gao, Xiang, Wells, Richard A., Szer, Jeff
Publicado 2020

Characterization of breakthrough hemolysis events observed in the phase III randomized studies of ravulizumab versus eculizumab in adults with paroxysmal nocturnal hemoglobinuria

por Brodsky, Robert A., de Latour, Régis Peffault, Rottinghaus, Scott T., Röth, Alexander, Risitano, Antonio M., Weitz, Ilene C., Hillmen, Peter, Maciejewski, Jaroslaw P., Szer, Jeff, Lee, Jong Wook, Kulasekararaj, Austin G., Volles, Lori, Damokosh, Andrew I., Ortiz, Stephan, Shafner, Lori, Liu, Peng, Hill, Anita, Schrezenmeier, Hubert
Publicado 2020