Increased Expression of Laminin Subunit Alpha 1 Chain by dCas9-VP160

por Perrin, Arnaud, Rousseau, Joël, Tremblay, Jacques P.
Publicado 2017

The protective mutation A673T in amyloid precursor protein gene decreases Aβ peptides production for 14 forms of Familial Alzheimer’s Disease in SH-SY5Y cells

por Guyon, Antoine, Rousseau, Joël, Lamothe, Gabriel, Tremblay, Jacques P.
Publicado 2020

Prime Editing Permits the Introduction of Specific Mutations in the Gene Responsible for Duchenne Muscular Dystrophy

por Happi Mbakam, Cédric, Rousseau, Joël, Tremblay, Guillaume, Yameogo, Pouiré, Tremblay, Jacques P.
Publicado 2022

Insertion of the protective APP A673T mutation by CRISPR/Cas9 base editing or PRIME editing.

por Tremblay, Jacques, Guyon, Antoine, Rousseau, Joël, Tremblay, Guillaume, Begin, Francis-Gabriel, Lamothe, Gabriel
Publicado 2021

Increased Frataxin Expression Induced in Friedreich Ataxia Cells by Platinum TALE-VP64s or Platinum TALE-SunTag

por Cherif, Khadija, Gérard, Catherine, Rousseau, Joël, Ouellet, Dominique L., Chapdelaine, Pierre, Tremblay, Jacques P.
Publicado 2018

Base editing strategy for insertion of the A673T mutation in the APP gene to prevent the development of AD in vitro

por Guyon, Antoine, Rousseau, Joël, Bégin, Francis-Gabriel, Bertin, Tom, Lamothe, Gabriel, Tremblay, Jacques P.
Publicado 2021

Prime editing optimized RTT permits the correction of the c.8713C>T mutation in DMD gene

por Happi Mbakam, Cedric, Rousseau, Joel, Lu, Yaoyao, Bigot, Anne, Mamchaoui, Kamel, Mouly, Vincent, Tremblay, Jacques P.
Publicado 2022

Myoblasts Derived From Normal hESCs and Dystrophic hiPSCs Efficiently Fuse With Existing Muscle Fibers Following Transplantation

por Goudenege, Sébastien, Lebel, Carl, Huot, Nicolas B, Dufour, Christine, Fujii, Isao, Gekas, Jean, Rousseau, Joël, Tremblay, Jacques P
Publicado 2012

Efficient Restoration of the Dystrophin Gene Reading Frame and Protein Structure in DMD Myoblasts Using the CinDel Method

por Iyombe-Engembe, Jean-Paul, Ouellet, Dominique L, Barbeau, Xavier, Rousseau, Joël, Chapdelaine, Pierre, Lagüe, Patrick, Tremblay, Jacques P
Publicado 2016

Targeted Gene Addition of Microdystrophin in Mice Skeletal Muscle via Human Myoblast Transplantation

por Benabdallah, Basma F, Duval, Arnaud, Rousseau, Joel, Chapdelaine, Pierre, Holmes, Michael C, Haddad, Eli, Tremblay, Jacques P, Beauséjour, Christian M
Publicado 2013

Prime editing strategies to mediate exon skipping in DMD gene

por Happi Mbakam, Cedric, Roustant, Jeanne, Rousseau, Joel, Yameogo, Pouire, Lu, Yaoyao, Bigot, Anne, Mamchaoui, Kamel, Mouly, Vincent, Lamothe, Gabriel, Tremblay, Jacques P.
Publicado 2023