Neonatal AAV delivery of alpha-synuclein induces pathology in the adult mouse brain

por Delenclos, Marion, Faroqi, Ayman H., Yue, Mei, Kurti, Aishe, Castanedes-Casey, Monica, Rousseau, Linda, Phillips, Virginia, Dickson, Dennis W., Fryer, John D., McLean, Pamela J.
Publicado 2017

LRRK2 phosphorylates novel tau epitopes and promotes tauopathy

por Bailey, Rachel M., Covy, Jason P., Melrose, Heather L., Rousseau, Linda, Watkinson, Ruth, Knight, Joshua, Miles, Sarah, Farrer, Matthew J., Dickson, Dennis W., Giasson, Benoit I., Lewis, Jada
Publicado 2013

Tau deposition drives neuropathological, inflammatory and behavioral abnormalities independently of neuronal loss in a novel mouse model

por Cook, Casey, Kang, Silvia S., Carlomagno, Yari, Lin, Wen-Lang, Yue, Mei, Kurti, Aishe, Shinohara, Mitsuru, Jansen-West, Karen, Perkerson, Emilie, Castanedes-Casey, Monica, Rousseau, Linda, Phillips, Virginia, Bu, Guojun, Dickson, Dennis W., Petrucelli, Leonard, Fryer, John D.
Publicado 2015

Neuronal sensitivity to TDP-43 overexpression is dependent on timing of induction

por Cannon, Ashley, Yang, Baoli, Knight, Joshua, Farnham, Ian M., Zhang, Yongjie, Wuertzer, Charles A., D’Alton, Simon, Lin, Wen-lang, Castanedes-Casey, Monica, Rousseau, Linda, Scott, Brittany, Jurasic, Michael, Howard, John, Yu, Xin, Bailey, Rachel, Sarkisian, Matthew R., Dickson, Dennis W., Petrucelli, Leonard, Lewis, Jada
Publicado 2012

Loss of Tmem106b is unable to ameliorate frontotemporal dementia-like phenotypes in an AAV mouse model of C9ORF72-repeat induced toxicity

por Nicholson, Alexandra M., Zhou, Xiaolai, Perkerson, Ralph B., Parsons, Tammee M., Chew, Jeannie, Brooks, Mieu, DeJesus-Hernandez, Mariely, Finch, NiCole A., Matchett, Billie J., Kurti, Aishe, Jansen-West, Karen R., Perkerson, Emilie, Daughrity, Lillian, Castanedes-Casey, Monica, Rousseau, Linda, Phillips, Virginia, Hu, Fenghua, Gendron, Tania F., Murray, Melissa E., Dickson, Dennis W., Fryer, John D., Petrucelli, Leonard, Rademakers, Rosa
Publicado 2018

Age- and disease-dependent increase of the mitophagy marker phospho-ubiquitin in normal aging and Lewy body disease

por Hou, Xu, Fiesel, Fabienne C., Truban, Dominika, Castanedes Casey, Monica, Lin, Wen-lang, Soto, Alexandra I., Tacik, Pawel, Rousseau, Linda G., Diehl, Nancy N., Heckman, Michael G., Lorenzo-Betancor, Oswaldo, Ferrer, Isidre, Arbelo, José M., Steele, John C., Farrer, Matthew J., Cornejo-Olivas, Mario, Torres, Luis, Mata, Ignacio F., Graff-Radford, Neill R., Wszolek, Zbigniew K., Ross, Owen A., Murray, Melissa E., Dickson, Dennis W., Springer, Wolfdieter
Publicado 2018

In-depth clinico-pathological examination of RNA foci in a large cohort of C9ORF72 expansion carriers

por DeJesus-Hernandez, Mariely, Finch, NiCole A., Wang, Xue, Gendron, Tania F., Bieniek, Kevin F., Heckman, Michael G., Vasilevich, Aliaksei, Murray, Melissa E., Rousseau, Linda, Weesner, Rachael, Lucido, Anthony, Parsons, Meeia, Chew, Jeannie, Josephs, Keith A., Parisi, Joseph E., Knopman, David S., Petersen, Ronald C., Boeve, Bradley F., Graff-Radford, Neill R., de Boer, Jan, Asmann, Yan W., Petrucelli, Leonard, Boylan, Kevin B., Dickson, Dennis W., van Blitterswijk, Marka, Rademakers, Rosa
Publicado 2017

Cerebellar c9RAN proteins associate with clinical and neuropathological characteristics of C9ORF72 repeat expansion carriers

por Gendron, Tania F., van Blitterswijk, Marka, Bieniek, Kevin F., Daughrity, Lillian M., Jiang, Jie, Rush, Beth K., Pedraza, Otto, Lucas, John A., Murray, Melissa E., Desaro, Pamela, Robertson, Amelia, Overstreet, Karen, Thomas, Colleen S., Crook, Julia E., Castanedes-Casey, Monica, Rousseau, Linda, Josephs, Keith A., Parisi, Joseph E., Knopman, David S., Petersen, Ronald C., Boeve, Bradley F., Graff-Radford, Neill R., Rademakers, Rosa, Lagier-Tourenne, Clotilde, Edbauer, Dieter, Cleveland, Don W., Dickson, Dennis W., Petrucelli, Leonard, Boylan, Kevin B.
Publicado 2015