Modulation of NMDA receptor activity by CR4056, an imidazoline-2 receptor ligand with analgesic properties

por Puja, Giulia, Losi, Gabriele, Rovati, Lucio, Lanza, Marco, Caselli, Gianfranco, Bardoni, Rita
Publicado 2022

Efficacy of CR4056, a first-in-class imidazoline-2 analgesic drug, in comparison with naproxen in two rat models of osteoarthritis

por Comi, Eleonora, Lanza, Marco, Ferrari, Flora, Mauri, Valeria, Caselli, Gianfranco, Rovati, Lucio Claudio
Publicado 2017

Efficacy of CR3294, a new benzamidine derivative, in the prevention of 5-fluorouracil-induced gastrointestinal mucositis and diarrhea in mice

por Letari, Ornella, Booth, Catherine, Bonazzi, Albino, Garofalo, Paolo, Makovec, Francesco, Rovati, Lucio C., Caselli, Gianfranco
Publicado 2009

Experimental Pharmacology of Glucosamine Sulfate

por Chiusaroli, Riccardo, Piepoli, Tiziana, Zanelli, Tiziano, Ballanti, Paola, Lanza, Marco, Rovati, Lucio C., Caselli, Gianfranco
Publicado 2011

Crystalline Glucosamine Sulfate in the Treatment of Osteoarthritis: Evidence of Long-Term Cardiovascular Safety from Clinical Trials

por Palma dos Reis, Roberto, Giacovelli, Giampaolo, Girolami, Federica, André, Rui, Bonazzi, Albino, Rovati, Lucio C
Publicado 2011

The effect of maternal HMB supplementation on bone mechanical and geometrical properties, as well as histomorphometry and immunolocalization of VEGF, TIMP2, MMP13, BMP2 in the bone...

por Tomczyk-Warunek, Agnieszka, Blicharski, Tomasz, Jarecki, Jaromir, Dobrowolski, Piotr, Muszyński, Siemowit, Tomaszewska, Ewa, Rovati, Lucio C.
Publicado 2021

I2-Imidazoline Ligand CR4056 Improves Memory, Increases ApoE Expression and Reduces BBB Leakage in 5xFAD Mice

por Mota, Bibiana C., Ashburner, Nathan, Abelleira-Hervas, Laura, Liu, Liyueyue, Aleksynas, Robertas, Rovati, Lucio Claudio, Caselli, Gianfranco, Sastre, Magdalena
Publicado 2022

A randomised, double-blind, controlled trial comparing two intra-articular hyaluronic acid preparations differing by their molecular weight in symptomatic knee osteoarthritis

por Berenbaum, Francis, Grifka, Joachim, Cazzaniga, Sara, D'Amato, Massimo, Giacovelli, Giampaolo, Chevalier, Xavier, Rannou, Francois, Rovati, Lucio C, Maheu, Emmanuel
Publicado 2012

Improved efficacy, tolerance, safety, and abuse liability profile of the combination of CR4056 and morphine over morphine alone in rodent models

por Sala, Emanuele, Ferrari, Flora, Lanza, Marco, Milia, Chiara, Sabatini, Chiara, Bonazzi, Albino, Comi, Eleonora, Borsi Franchini, Miriam, Caselli, Gianfranco, Rovati, Lucio Claudio
Publicado 2020

Ferulated Poly(vinyl alcohol) based hydrogels()

por Pepi, Simone, Paolino, Marco, Saletti, Mario, Venditti, Jacopo, Talarico, Luigi, Andreassi, Marco, Giuliani, Germano, Caselli, Gianfranco, Artusi, Roberto, Cappelli, Andrea, Leone, Gemma, Magnani, Agnese, Rovati, Lucio
Publicado 2023

Pharmacological characterisation of CR6086, a potent prostaglandin E(2) receptor 4 antagonist, as a new potential disease-modifying anti-rheumatic drug

por Caselli, Gianfranco, Bonazzi, Albino, Lanza, Marco, Ferrari, Flora, Maggioni, Daniele, Ferioli, Cristian, Giambelli, Roberto, Comi, Eleonora, Zerbi, Silvia, Perrella, Marco, Letari, Ornella, Di Luccio, Elena, Colovic, Milena, Persiani, Stefano, Zanelli, Tiziano, Mennuni, Laura, Piepoli, Tiziana, Rovati, Lucio Claudio
Publicado 2018

A first-in-human trial on the safety and immunogenicity of COVID-eVax, a cellular response-skewed DNA vaccine against COVID-19

por Aurisicchio, Luigi, Brambilla, Nadia, Cazzaniga, Marina E., Bonfanti, Paolo, Milleri, Stefano, Ascierto, Paolo A., Capici, Serena, Vitalini, Cristina, Girolami, Federica, Giacovelli, Giampaolo, Caselli, Gianfranco, Visintin, Michela, Fanti, Francesca, Ghirri, Matteo, Conforti, Antonella, Compagnone, Mirco, Lione, Lucia, Salvatori, Erika, Pinto, Eleonora, Muzi, Alessia, Marra, Emanuele, Palombo, Fabio, Roscilli, Giuseppe, Manenti, Alessandro, Montomoli, Emanuele, Cadossi, Matteo, Rovati, Lucio C.
Publicado 2023

Can We Identify Patients with High Risk of Osteoarthritis Progression Who Will Respond to Treatment? A Focus on Biomarkers and Frailty

por Arden, Nigel, Richette, Pascal, Cooper, Cyrus, Bruyère, Olivier, Abadie, Eric, Branco, Jaime, Brandi, Maria Luisa, Berenbaum, Francis, Clerc, Cécile, Dennison, Elaine, Devogelaer, Jean-Pierre, Hochberg, Marc, D’Hooghe, Pieter, Herrero-Beaumont, Gabriel, Kanis, John A., Laslop, Andrea, Leblanc, Véronique, Maggi, Stefania, Mautone, Giuseppe, Pelletier, Jean-Pierre, Petit-Dop, Florence, Reiter-Niesert, Susanne, Rizzoli, René, Rovati, Lucio, Tajana Messi, Eleonora, Tsouderos, Yannis, Martel-Pelletier, Johanne, Reginster, Jean-Yves
Publicado 2015

COVID-eVax, an electroporated DNA vaccine candidate encoding the SARS-CoV-2 RBD, elicits protective responses in animal models

por Conforti, Antonella, Marra, Emanuele, Palombo, Fabio, Roscilli, Giuseppe, Ravà, Micol, Fumagalli, Valeria, Muzi, Alessia, Maffei, Mariano, Luberto, Laura, Lione, Lucia, Salvatori, Erika, Compagnone, Mirco, Pinto, Eleonora, Pavoni, Emiliano, Bucci, Federica, Vitagliano, Grazia, Stoppoloni, Daniela, Pacello, Maria Lucrezia, Cappelletti, Manuela, Ferrara, Fabiana Fosca, D’Acunto, Emanuela, Chiarini, Valerio, Arriga, Roberto, Nyska, Abraham, Di Lucia, Pietro, Marotta, Davide, Bono, Elisa, Giustini, Leonardo, Sala, Eleonora, Perucchini, Chiara, Paterson, Jemma, Ryan, Kathryn Ann, Challis, Amy-Rose, Matusali, Giulia, Colavita, Francesca, Caselli, Gianfranco, Criscuolo, Elena, Clementi, Nicola, Mancini, Nicasio, Groß, Rüdiger, Seidel, Alina, Wettstein, Lukas, Münch, Jan, Donnici, Lorena, Conti, Matteo, De Francesco, Raffaele, Kuka, Mirela, Ciliberto, Gennaro, Castilletti, Concetta, Capobianchi, Maria Rosaria, Ippolito, Giuseppe, Guidotti, Luca G., Rovati, Lucio, Iannacone, Matteo, Aurisicchio, Luigi
Publicado 2022