Modelling Sporadic Alzheimer’s Disease Using Induced Pluripotent Stem Cells

por Rowland, Helen A., Hooper, Nigel M., Kellett, Katherine A. B.
Publicado 2018

Temporal transcriptional control of neural induction in human induced pluripotent stem cells

por Gupta, Shakti, Polit, Lucia Dutan, Fitzgerald, Michael, Rowland, Helen A., Murali, Divya, Buckley, Noel J., Subramaniam, Shankar
Publicado 2023

Inhibition of insulin-degrading enzyme in human neurons promotes amyloid-β deposition

por Rowland, Helen A., Moxon, Samuel R., Corbett, Nicola J., Hanson, Kelsey, Fisher, Kate, Kellett, Katherine A.B., Hooper, Nigel M.
Publicado 2023

Proteolytic shedding of the prion protein via activation of metallopeptidase ADAM10 reduces cellular binding and toxicity of amyloid-β oligomers

por Jarosz-Griffiths, Heledd H., Corbett, Nicola J., Rowland, Helen A., Fisher, Kate, Jones, Alys C., Baron, Jennifer, Howell, Gareth J., Cowley, Sally A., Chintawar, Satyan, Cader, M. Zameel, Kellett, Katherine A. B., Hooper, Nigel M.
Publicado 2019

Neurons derived from individual early Alzheimer’s disease patients reflect their clinical vulnerability

por Ng, Bryan, Rowland, Helen A, Wei, Tina, Arunasalam, Kanisa, Hayes, Emma Mee, Koychev, Ivan, Hedegaard, Anne, Ribe, Elena M, Chan, Dennis, Chessell, Tharani, Ffytche, Dominic, Gunn, Roger N, Kocagoncu, Ece, Lawson, Jennifer, Malhotra, Paresh A, Ridha, Basil H, Rowe, James B, Thomas, Alan J, Zamboni, Giovanna, Buckley, Noel J, Cader, Zameel M, Lovestone, Simon, Wade-Martins, Richard
Publicado 2022