On-target IgG hexamerisation driven by a C-terminal IgM tail-piece fusion variant confers augmented complement activation

por Sopp, Joshua M., Peters, Shirley J., Rowley, Tania F., Oldham, Robert J., James, Sonya, Mockridge, Ian, French, Ruth R., Turner, Alison, Beers, Stephen A., Humphreys, David P., Cragg, Mark S.
Publicado 2021

Impact of Human FcγR Gene Polymorphisms on IgG-Triggered Cytokine Release: Critical Importance of Cell Assay Format

por Hussain, Khiyam, Hargreaves, Chantal E., Rowley, Tania F., Sopp, Joshua M., Latham, Kate V., Bhatta, Pallavi, Sherington, John, Cutler, Rona M., Humphreys, David P., Glennie, Martin J., Strefford, Jonathan C., Cragg, Mark S.
Publicado 2019

The Death Receptor 3–TNF-like protein 1A pathway drives adverse bone pathology in inflammatory arthritis

por Bull, Melanie Jane, Williams, Anwen Siân, Mecklenburgh, Zarabeth, Calder, Claudia Jane, Twohig, Jason Peter, Elford, Carole, Evans, Bronwen Alice James, Rowley, Tania F., Slebioda, Tomasz J., Taraban, Vadim Y., Al-Shamkhani, Aymen, Wang, Eddie Chung Yern
Publicado 2008

Engineered hexavalent Fc proteins with enhanced Fc-gamma receptor avidity provide insights into immune-complex interactions

por Rowley, Tania F., Peters, Shirley J., Aylott, Mike, Griffin, Robert, Davies, Nicola L., Healy, Louise J., Cutler, Rona M., Eddleston, Alison, Pither, Thomas L., Sopp, Joshua M., Zaccheo, Oliver, Fossati, Gianluca, Cain, Katharine, Ventom, Andrew M., Hailu, Hanna, Ward, Eleanor J., Sherington, John, Brennan, Frank R., Fallah-Arani, Farnaz, Humphreys, David P.
Publicado 2018