Collagen abundance controls melanoma phenotypes through lineage-specific microenvironment sensing

por Miskolczi, Zsofia, Smith, Michael P., Rowling, Emily J., Ferguson, Jennifer, Barriuso, Jorge, Wellbrock, Claudia
Publicado 2018

A PAX3/BRN2 rheostat controls the dynamics of BRAF mediated MITF regulation in MITF(high)/AXL(low) melanoma

por Smith, Michael P., Rana, Sareena, Ferguson, Jennifer, Rowling, Emily J., Flaherty, Keith T., Wargo, Jennifer A., Marais, Richard, Wellbrock, Claudia
Publicado 2018

Cooperative behaviour and phenotype plasticity evolve during melanoma progression

por Rowling, Emily J., Miskolczi, Zsofia, Nagaraju, Raghavendar, Wilcock, Daniel J., Wang, Ping, Telfer, Brian, Li, Yaoyong, Lasheras-Otero, Irene, Redondo-Muñoz, Marta, Sharrocks, Andrew D., Arozarena, Imanol, Wellbrock, Claudia
Publicado 2020

Phosphatidylinositide 3-kinase (PI3K) and PI3K-related kinase (PIKK) activity contributes to radioresistance in thyroid carcinomas

por Burrows, Natalie, Williams, Joseph, Telfer, Brian A, Resch, Julia, Valentine, Helen R, Fitzmaurice, Richard J, Eustace, Amanda, Irlam, Joely, Rowling, Emily J, Hoang-Vu, Cuong, West, Catharine M, Brabant, Georg, Williams, Kaye J
Publicado 2016

Inhibiting Drivers of Non-mutational Drug Tolerance Is a Salvage Strategy for Targeted Melanoma Therapy

por Smith, Michael P., Brunton, Holly, Rowling, Emily J., Ferguson, Jennifer, Arozarena, Imanol, Miskolczi, Zsofia, Lee, Jessica L., Girotti, Maria R., Marais, Richard, Levesque, Mitchell P., Dummer, Reinhard, Frederick, Dennie T., Flaherty, Keith T., Cooper, Zachary A., Wargo, Jennifer A., Wellbrock, Claudia
Publicado 2016

An adaptive signaling network in melanoma inflammatory niches confers tolerance to MAPK signaling inhibition

por Young, Helen L., Rowling, Emily J., Bugatti, Mattia, Giurisato, Emanuele, Luheshi, Nadia, Arozarena, Imanol, Acosta, Juan-Carlos, Kamarashev, Jivko, Frederick, Dennie T., Cooper, Zachary A., Reuben, Alexandre, Gil, Jesus, Flaherty, Keith T., Wargo, Jennifer A., Vermi, William, Smith, Michael P., Wellbrock, Claudia, Hurlstone, Adam
Publicado 2017

Targeting endothelin receptor signalling overcomes heterogeneity driven therapy failure

por Smith, Michael P, Rowling, Emily J, Miskolczi, Zsofia, Ferguson, Jennifer, Spoerri, Loredana, Haass, Nikolas K, Sloss, Olivia, McEntegart, Sophie, Arozarena, Imanol, von Kriegsheim, Alex, Rodriguez, Javier, Brunton, Holly, Kmarashev, Jivko, Levesque, Mitchell P, Dummer, Reinhard, Frederick, Dennie T, Andrews, Miles C, Cooper, Zachary A, Flaherty, Keith T, Wargo, Jennifer A, Wellbrock, Claudia
Publicado 2017