Caspase-6 Knockout in the 5xFAD Model of Alzheimer’s Disease Reveals Favorable Outcome on Memory and Neurological Hallmarks

por Angel, Ariel, Volkman, Rotem, Royal, Tabitha Grace, Offen, Daniel
Publicado 2020

Antibody-Mediated Inhibition of Insulin-Degrading Enzyme Improves Insulin Activity in a Diabetic Mouse Model

por Fursht, Ofir, Liran, Mirit, Nash, Yuval, Medala, Vijay Krishna, Ini, Dor, Royal, Tabitha Grace, Goldsmith, Guy, Nahary, Limor, Benhar, Itai, Frenkel, Dan
Publicado 2022

Loss of insulin signaling in astrocytes exacerbates Alzheimer-like phenotypes in a 5xFAD mouse model

por Chen, Wenqiang, Huang, Qian, Lazdon, Ekaterina Katie, Gomes, Antonio, Wong, Marisa, Stephens, Emily, Royal, Tabitha Grace, Frenkel, Dan, Cai, Weikang, Kahn, C. Ronald
Publicado 2023

Physiological expression of mutated TAU impaired astrocyte activity and exacerbates β-amyloid pathology in 5xFAD mice

por Farfara, Dorit, Sooliman, Meital, Avrahami, Limor, Royal, Tabitha Grace, Amram, Shoshik, Rozenstein-Tsalkovich, Lea, Trudler, Dorit, Blanga-Kanfi, Shani, Eldar-Finkelman, Hagit, Pahnke, Jens, Rosenmann, Hanna, Frenkel, Dan
Publicado 2023