Inhibition of the T cell oxygen sensing machinery promotes anti-tumor efficacy

por Clever, David, Roychoudhuri, Rahul, Restifo, Nicholas P
Publicado 2015

Regulation of regulatory T cells in cancer

por Stockis, Julie, Roychoudhuri, Rahul, Halim, Timotheus Y. F.
Publicado 2019

Increased cardiovascular mortality more than fifteen years after radiotherapy for breast cancer: a population-based study

por Roychoudhuri, Rahul, Robinson, David, Putcha, Venkata, Cuzick, Jack, Darby, Sarah, Møller, Henrik
Publicado 2007

Elevated potassium levels suppress T cell activation within tumors

por Eil, Robert L, Roychoudhuri, Rahul, Clever, David, Patel, Shashank, Sukumar, Madhu, Pan, Jenny H, Palmer, Douglas, Klebanoff, Christopher A, Restifo, Nicholas P
Publicado 2015

Identification of the Genomic Insertion Site of Pmel-1 TCR α and β Transgenes by Next-Generation Sequencing

por Ji, Yun, Abrams, Natalie, Zhu, Wei, Salinas, Eddie, Yu, Zhiya, Palmer, Douglas C., Jailwala, Parthav, Franco, Zulmarie, Roychoudhuri, Rahul, Stahlberg, Eric, Gattinoni, Luca, Restifo, Nicholas P.
Publicado 2014

Cish actively silences tcr signaling in CD8+ T cells to maintain tumor tolerance

por Palmer, Douglas, Guittard, Geoff, Franco, Zulmarie, Patel, Shashank, Klebanoff, Christopher A, Sukumar, Madhusudhanan, Eil, Robert L, Clever, David, Balagopalan, Lakshmi, Roychoudhuri, Rahul, Samelson, Larry, Restifo, Nicholas
Publicado 2015

Modulating immunometabolism of tumor specific mouse and human lymphocytes to enhance T cell based therapy for cancer

por Sukumar, Madhusudhanan, Liu, Jie, Patel, Shashank J, Klebanoff, Christopher A, Mehta, Gautam, Roychoudhuri, Rahul, Crompton, Joseph, Clever, David, Gattinoni, Luca, Muranski, Pawel, Finkel, Toren, Restifo, Nicholas
Publicado 2015

A cell-based bioluminescence assay reveals dose-dependent and contextual repression of AP-1-driven gene expression by BACH2

por Vardaka, Panagiota, Lozano, Teresa, Bot, Christopher, Ellery, Jonathan, Whiteside, Sarah K., Imianowski, Charlotte J., Farrow, Stuart, Walker, Simon, Okkenhaug, Hanneke, Yang, Jie, Okkenhaug, Klaus, Kuo, Paula, Roychoudhuri, Rahul
Publicado 2020

Immunotherapy generates selective pressure for acquisition of immunogenic neoantigens in escape tumors

por Pan, Jenny H, Vodnala, Suman, Eil, Robert L, Yu, Zhiya, Gartner, Jared J, Clever, David, Roychoudhuri, Rahul, Patel, Shashank J, Klebanoff, Christopher A, Sukumar, Madhusudhanan, Yamamoto, Tori, Restifo, Nicholas P
Publicado 2015

BACH2 represses effector programmes to stabilize Treg-mediated immune homeostasis - a new target in tumor immunotherapy?

por Roychoudhuri, Rahul, Hirahara, Kiyoshi, Mousavi, Kambiz, Clever, David, Bonelli, Michael, Klebanoff, Christopher, Sartorelli, Vittorio, Kanno, Yuka, Gattinoni, Luca, Wang, Ena, Liu, Hui, Marincola, Franco, Kazuhiko, Igarashi, O’Shea, John, Restifo, Nicholas P
Publicado 2013

Stretch-Enhancers Delineate Disease-Associated Regulatory Nodes in T Cells

por Vahedi, Golnaz, Kanno, Yuka, Furumoto, Yasuko, Jiang, Kan, Parker, Stephen C., Erdos, Michael, Davis, Sean R., Roychoudhuri, Rahul, Restifo, Nicholas P., Gadina, Massimo, Tang, Zhonghui, Ruan, Yijun, Collins, Francis S., Sartorelli, Vittorio, O’Shea, John J.
Publicado 2015

Transcriptional repressor ZEB2 promotes terminal differentiation of CD8(+) effector and memory T cell populations during infection

por Omilusik, Kyla D., Best, J. Adam, Yu, Bingfei, Goossens, Steven, Weidemann, Alexander, Nguyen, Jessica V., Seuntjens, Eve, Stryjewska, Agata, Zweier, Christiane, Roychoudhuri, Rahul, Gattinoni, Luca, Bird, Lynne M., Higashi, Yujiro, Kondoh, Hisato, Huylebroeck, Danny, Haigh, Jody, Goldrath, Ananda W.
Publicado 2015

Lineage relationship of CD8(+) T cell subsets is revealed by progressive changes in the epigenetic landscape

por Crompton, Joseph G., Narayanan, Manikandan, Cuddapah, Suresh, Roychoudhuri, Rahul, Ji, Yun, Yang, Wenjing, Patel, Shashank J., Sukumar, Madhusudhanan, Palmer, Douglas C., Peng, Weiqun, Wang, Ena, Marincola, Francesco M., Klebanoff, Christopher A., Zhao, Keji, Tsang, John S., Gattinoni, Luca, Restifo, Nicholas P.
Publicado 2016

BACH2 drives quiescence and maintenance of resting Treg cells to promote homeostasis and cancer immunosuppression

por Grant, Francis M., Yang, Jie, Nasrallah, Rabab, Clarke, James, Sadiyah, Firas, Whiteside, Sarah K., Imianowski, Charlotte J., Kuo, Paula, Vardaka, Panagiota, Todorov, Tihomir, Zandhuis, Nordin, Patrascan, Ilinca, Tough, David F., Kometani, Kohei, Eil, Robert, Kurosaki, Tomohiro, Okkenhaug, Klaus, Roychoudhuri, Rahul
Publicado 2020

CCR8 marks highly suppressive Treg cells within tumours but is dispensable for their accumulation and suppressive function

por Whiteside, Sarah K., Grant, Francis M., Gyori, David S., Conti, Alberto G., Imianowski, Charlotte J., Kuo, Paula, Nasrallah, Rabab, Sadiyah, Firas, Lira, Sergio A., Tacke, Frank, Eil, Robert L., Burton, Oliver T., Dooley, James, Liston, Adrian, Okkenhaug, Klaus, Yang, Jie, Roychoudhuri, Rahul
Publicado 2021

Permissivity of the NCI-60 cancer cell lines to oncolytic Vaccinia Virus GLV-1h68

por Ascierto, Maria Libera, Worschech, Andrea, Yu, Zhiya, Adams, Sharon, Reinboth, Jennifer, Chen, Nanhai G, Pos, Zoltan, Roychoudhuri, Rahul, Di Pasquale, Giovanni, Bedognetti, Davide, Uccellini, Lorenzo, Rossano, Fabio, Ascierto, Paolo A, Stroncek, David F, Restifo, Nicholas P, Wang, Ena, Szalay, Aladar A, Marincola, Francesco M
Publicado 2011

Ionic immune suppression within the tumour microenvironment limits T cell effector function

por Eil, Robert, Vodnala, Suman K, Clever, David, Klebanoff, Christopher A, Sukumar, Madhusudhanan, Pan, Jenny H, Palmer, Douglas C, Gros, Alena, Yamamoto, Tori N, Patel, Shashank J, Guittard, Geoffrey C, Yu, Zhiya, Carbonaro, Valentina, Okkenhaug, Klaus, Schrump, David S, Linehan, W Marston, Roychoudhuri, Rahul, Restifo, Nicholas P
Publicado 2016

Cish actively silences TCR signaling in CD8(+) T cells to maintain tumor tolerance

por Palmer, Douglas C., Guittard, Geoffrey C., Franco, Zulmarie, Crompton, Joseph G., Eil, Robert L., Patel, Shashank J., Ji, Yun, Van Panhuys, Nicholas, Klebanoff, Christopher A., Sukumar, Madhusudhanan, Clever, David, Chichura, Anna, Roychoudhuri, Rahul, Varma, Rajat, Wang, Ena, Gattinoni, Luca, Marincola, Francesco M., Balagopalan, Lakshmi, Samelson, Lawrence E., Restifo, Nicholas P.
Publicado 2015

The transcription factor c-Myb regulates CD8(+) T cell stemness and antitumor immunity

por Gautam, Sanjivan, Fioravanti, Jessica, Zhu, Wei, Le Gall, John B., Brohawn, Philip, Lacey, Neal E., Hu, Jinhui, Hocker, James D., Hawk, Nga Voong, Kapoor, Veena, Telford, William G., Gurusamy, Devikala, Yu, Zhiya, Bhandoola, Avinash, Xue, Hai-Hui, Roychoudhuri, Rahul, Higgs, Brandon W., Restifo, Nicholas P., Bender, Timothy P., Ji, Yun, Gattinoni, Luca
Publicado 2019

BACH2 restricts NK cell maturation and function, limiting immunity to cancer metastasis

por Imianowski, Charlotte J., Whiteside, Sarah K., Lozano, Teresa, Evans, Alexander C., Benson, Jayme D., Courreges, Christina J.F., Sadiyah, Firas, Lau, Colleen M., Zandhuis, Nordin D., Grant, Francis M., Schuijs, Martijn J., Vardaka, Panagiota, Kuo, Paula, Soilleux, Elizabeth J., Yang, Jie, Sun, Joseph C., Kurosaki, Tomohiro, Okkenhaug, Klaus, Halim, Timotheus Y.F., Roychoudhuri, Rahul
Publicado 2022